Clinical trials · Pennsylvania
Infections clinical trials in Pennsylvania
We’re tracking 87 recruiting infections studies with a site in Pennsylvania — including Early Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT05947071RecruitingPhase 2
Higher-dose flu vaccine versus standard dose in child transplant patients
This trial compares a higher-dose flu vaccine to the standard dose in children who recently received a kidney, heart, and/or liver transplant. It aims to see which dose better protects children against influenza while checking for safety.
Pittsburgh, PennsylvaniaAges 3–17 - NCT06738407RecruitingPhase 4
Doxycycline to prevent STIs in high-risk people
This study tests whether taking a daily antibiotic (doxycycline) can prevent sexually transmitted infections in people at high risk. If you've had an STI recently and sometimes have sex without condoms, you might be able to join.
Philadelphia, PennsylvaniaAges 13–29 - NCT06807840Recruiting
Flu infection study at Penn Medicine
This study looks at how people's immune systems respond to the flu. If you have a positive flu test at a Penn Medicine location and are 18 or older, you may be able to join.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Philadelphia, PennsylvaniaAges 40–60 - NCT07322146Enrolling by invitationPhase 4
Shorter antibiotics for children with common infections
This study tests whether shorter courses of antibiotics are as effective as longer ones for children hospitalized with pneumonia, skin infections, or urinary tract infections. It may help children get back to normal faster and reduce side effects.
Pittsburgh, PennsylvaniaAges 2 months–17 years - NCT07009548Enrolling by invitationPhase 4
CytoGam for CMV in solid organ transplant recipients
This trial tests whether adding CytoGam (an antibody treatment) to standard antiviral therapy can better treat CMV (a common virus) in people who have received a solid organ transplant. It may help those with high virus levels or a new infection after transplant.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06774144Enrolling by invitationPhase 3
Rezafungin to prevent fungal infections in liver transplant patients
This trial tests whether a medicine called rezafungin can help prevent serious fungal infections in people who have received a liver transplant. If you have certain risk factors, this study may offer extra protection against infections.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06472765Enrolling by invitation
Study of the Vaginal Ecosystem in Healthy Women
This study looks at the natural balance of bacteria and other factors in the vagina of healthy women. It aims to learn more about what a healthy vaginal ecosystem looks like.
Bryn Mawr, PennsylvaniaAges 18–89 - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Pittsburgh, PennsylvaniaAges 6 years+ - NCT06027879Enrolling by invitationPhase 1/Phase 2
Anti-viral T-cell therapy for stubborn viral infections after transplant
This trial tests a treatment using specially grown T-cells (a type of immune cell) to fight certain viruses that won't go away with standard medicines. It is for people who have had a stem cell or organ transplant, or who have a weak immune system, and who are struggling with adenovirus, CMV, or EBV infections.
Pittsburgh, PennsylvaniaAges 1 month–65 years - NCT07610395RecruitingPhase 2
Testing an oral drug for cold virus in COPD patients
This trial tests an oral medication (VPV) to see if it can safely treat rhinovirus (a common cold virus) in people with COPD. The goal is to help you recover faster and prevent serious COPD flare-ups.
DuBois, PennsylvaniaAges 40–85 - NCT06495021Recruiting
Osteopathic manipulation for newly diagnosed respiratory illness in older adults
This study tests whether osteopathic manipulation (a gentle hands-on treatment) helps older adults recover from common respiratory illnesses like bronchitis or pneumonia when added to regular care. It may be a good option for you if you're 65 or older and have just been diagnosed with a respiratory infection.
Bloomsburg, PennsylvaniaAges 65–100 - NCT07336134Recruiting
HPV self-test for cervical health
This study offers a way to screen for cervical cancer using an HPV self-test. It is designed for women who may not have had a recent Pap smear and are from certain minority groups.
Philadelphia, PennsylvaniaAges 25–65 - NCT07013474RecruitingPhase 3
Study of ibuzatrelvir for immunocompromised adults with COVID-19
This trial tests an investigational medicine called ibuzatrelvir for adults with COVID-19 who have a weakened immune system. The study aims to see if it helps them recover and avoid severe illness.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT02140255RecruitingPhase 1/Phase 2
Intensive early HIV treatment in newborns to aim for remission
This study gives very early, intensive HIV medicine to infants diagnosed with HIV and follows them closely to see if HIV can go into remission (stop being detectable without ongoing treatment). It may help families understand whether treating right after birth can change a child’s long-term HIV outlook.
Philadelphia, PennsylvaniaAges Up to 2 days - NCT07645287RecruitingPhase 2
New HIV Combination Therapy for People on Biktarvy
This study tests a new HIV medication (GS-3242) combined with lenacapavir against your current Biktarvy regimen. Both are all-oral treatments for people whose HIV is well-controlled.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Philadelphia, PennsylvaniaAges 18–64 - NCT06071767RecruitingPhase 1/Phase 2
Immune therapy trial for early-treated HIV
This study tests whether a combination of three immune therapies can help control HIV without daily medication. You may qualify if you started HIV treatment very early and have had a suppressed viral load for at least a year.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04293042RecruitingEarly Phase 1
BK virus treatment using donor immune cells after transplant
This early-phase study tests whether immune cells made from a donor (T cells) can treat BK virus infection in people whose immune system is weak after a stem cell transplant or chemotherapy. It may help control the virus causing bladder/urinary symptoms.
Philadelphia, PennsylvaniaAges 1 month–25 years - NCT05653232Recruiting
Preventing hepatitis C in kidney transplant recipients using antiviral pills
This study tests antiviral medicine given around the time of a kidney transplant to prevent hepatitis C infection when the donor has hepatitis C. It may help uninfected recipients stay hepatitis C–free after receiving the kidney.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06601803Enrolling by invitationPhase 4
Surgical preparation study for first-time shoulder replacement
This trial tests a surgical prep solution called Surgiphor during first-time total shoulder replacement. It aims to help prevent infections.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07211997Recruiting
FebriDx test for fever and cold symptoms in children
This study tests a finger-prick blood test (FebriDx) to see if it can quickly tell whether a child's fever and cold symptoms are caused by a bacterial or viral infection. If it works, it could help doctors decide whether antibiotics are needed.
Pittsburgh, PennsylvaniaAges 2–11 - NCT07650916RecruitingPhase 3
A study of two ultra-long-acting HIV shots
This trial tests a new ultra-long-acting injectable combination of cabotegravir and rilpivirine for people with HIV who already have the virus under control. It aims to see if these shots can keep the virus suppressed with fewer doses.
Philadelphia, PennsylvaniaAges 12 years+ - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Uniontown, PennsylvaniaAges 12 years+
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting infections studies listed above.
- University of Pittsburgh Medical Center · 3 studies
- UPMC Presbyterian Hospital · 3 studies
- UPMC Children's Hospital of Pittsburgh · 2 studies
- Center for Pelvic Medicine
- Children's Hospital of Philadelphia
- Clinical Research Associates of Central Pennsylvania
- Geisinger
- GSK Investigational Site
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in Pennsylvania?
- Yes. We're currently tracking 87 recruiting infections studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.