Clinical trials · Pennsylvania
Infections clinical trials in Pennsylvania
We’re tracking 86 recruiting infections studies with a site in Pennsylvania — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06003192Recruiting
Screen Smart: Boosting HIV testing in teens
This trial tests a digital health tool to help increase HIV screening and prevention among teenagers visiting the emergency department. If you are 15 to 21 years old, you may be able to join and help improve how we offer these services.
Philadelphia, PennsylvaniaAges 15–21 - NCT07022678RecruitingPhase 3
Xylitol dental wipes to reduce infection risk in childhood leukemia
This trial tests whether using xylitol dental wipes can lower the risk of bloodstream infections in children with acute myeloid leukemia (AML) who are receiving chemotherapy. If you or your child have AML and will have at least two cycles of chemo that include cytarabine, this study may help reduce infection risk.
Philadelphia, PennsylvaniaAges 1–25 - NCT07013474RecruitingPhase 3
Study of ibuzatrelvir for immunocompromised adults with COVID-19
This trial tests an investigational medicine called ibuzatrelvir for adults with COVID-19 who have a weakened immune system. The study aims to see if it helps them recover and avoid severe illness.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06950892Recruiting
Remote sputum collection study for cystic fibrosis
This study tests if people with cystic fibrosis can collect sputum samples at home and mail them in, instead of coming to the clinic. It aims to make participation easier for patients.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06938867RecruitingPhase 1/Phase 2
Study of SNIPR001 for stem cell transplant patients
This trial tests an oral treatment called SNIPR001 that targets a type of E. coli bacteria resistant to common antibiotics. It may help prevent infections during stem cell transplant recovery.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06876259Recruiting
AI tool to reduce antibiotics for young children with colds
This trial tests whether an artificial intelligence (AI) tool can help doctors decide when antibiotics are not needed for young children with colds. It aims to reduce unnecessary antibiotic use.
Pittsburgh, PennsylvaniaAges 6 months–2 years - NCT06877793Recruiting
Using dye imaging to diagnose severe flesh-eating infections
This trial tests a new way to quickly diagnose necrotizing soft tissue infections (NSTIs, also called flesh-eating infections) using a safe dye and a camera. If you are being checked for a possible NSTI, this could help doctors decide faster whether you have it and need treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06839456RecruitingPhase 1/Phase 2
Stem cell addback to prevent infections after transplant
This trial tests whether adding back certain immune cells after a stem cell transplant can help prevent serious viral or fungal infections. It's for children and young adults up to age 25 who need a transplant for a blood cancer or other curable disease.
Philadelphia, PennsylvaniaAges 1 month–25 years - NCT06765135Enrolling by invitation
Respiratory test for smarter antibiotic use
This trial tests a quick, point-of-care test for respiratory infections in primary care. The goal is to help doctors decide when antibiotics are needed, reducing unnecessary use.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03266640RecruitingPhase 2
CMV cell therapy for difficult-to-treat viral infection
This trial tests an immune cell treatment (CMV-specific cytotoxic T cells) for people with a CMV infection that is not improving despite standard antivirals, or who cannot tolerate them. If eligible, the treatment aims to help the body control the virus after transplant-related immune problems.
Philadelphia, PennsylvaniaAges 1 month–79 years - NCT03266627RecruitingPhase 2
Adenovirus T-cell therapy for hard-to-treat virus after transplants
This trial tests a special immune-cell treatment made to fight adenovirus in people whose adenovirus infection keeps coming back or won’t improve after transplant. It may help control infection when standard antiviral medicines are not working or can’t be tolerated.
Philadelphia, PennsylvaniaAges 1 month–79 years - NCT06665646RecruitingPhase 1
HIV vaccine booster study for previous trial participants
This study tests a booster vaccine for HIV in people who were part of an earlier HIV vaccine trial. The goal is to see if it's safe and helps the immune system fight HIV better.
Philadelphia, PennsylvaniaAges 18–60 - NCT06544928Enrolling by invitation
Home monitoring for COPD flare-ups after hospital discharge
This study tests a wearable device that listens to your breathing at home. It may help detect early signs of a COPD flare-up so you can get care sooner. You can join if you have moderate to severe COPD and recently left the hospital for a flare-up.
Philadelphia, PennsylvaniaAges 40–80 - NCT06495021Recruiting
Osteopathic manipulation for newly diagnosed respiratory illness in older adults
This study tests whether osteopathic manipulation (a gentle hands-on treatment) helps older adults recover from common respiratory illnesses like bronchitis or pneumonia when added to regular care. It may be a good option for you if you're 65 or older and have just been diagnosed with a respiratory infection.
Bloomsburg, PennsylvaniaAges 65–100 - NCT06399302Recruiting
Improving outcomes for lung transplant patients
This study looks at ways to improve outcomes for people who are waiting for or have recently received a lung transplant. It aims to find better management strategies for both donors and recipients.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04294043RecruitingPhase 1
Gallium IV study for adults with cystic fibrosis and NTM lung infection
This Phase 1 study tests whether an IV medicine called gallium can treat hard-to-treat lung infections (NTM) in adults with cystic fibrosis. It is mainly for people who have not been treated yet for NTM or who have NTM that has not cleared despite antibiotics.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06076304RecruitingPhase 4
Comparing treatments for acute sinusitis
This trial tests whether nasal steroids, nasal irrigation, or oral antibiotics work best for acute sinusitis. It may help if you have ongoing sinus symptoms or a 'double-sickening' pattern after a cold.
Hershey, PennsylvaniaAges 18–75 - NCT06080698Recruiting
Oral antibiotics for bloodstream infection trial
This trial tests whether switching from IV to oral antibiotics is just as effective for treating Gram-negative bloodstream infections. If you qualify, you may receive either continued IV antibiotics or switch to pills, with follow-up on your recovery and quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06056297RecruitingPhase 3
Study of Mavorixafor for chronic neutropenia with infections
This trial tests if mavorixafor can help people with certain types of long-term low neutrophil counts (chronic neutropenia) who still get frequent or serious infections. It aims to reduce infection risk by boosting your body's infection-fighting cells.
Philadelphia, PennsylvaniaAges 12 years+ - NCT05978141Recruiting
T-cell lymphoma registry study
This study creates a registry for people with certain T-cell or NK-cell lymphomas. It collects health information and tumor samples to learn more about these diseases and improve future treatments.
Philadelphia, PennsylvaniaAges Any age - NCT05947955RecruitingPhase 2
Study drug for infection-related lung failure in adults
This Phase 2 trial tests Rhu-pGSN in adults with acute respiratory distress syndrome (ARDS) caused by an infection. If you qualify, the study may help determine whether the drug improves outcomes in this short-term, life-threatening lung condition.
Hershey, PennsylvaniaAges 18 years+ - NCT04843111Recruiting
Registry study for pregnancy exposure to MenQuadfi vaccine
This is an observational registry that collects information about pregnant people and their babies when MenQuadfi® (a meningitis vaccine) was given during pregnancy or shortly before pregnancy. It helps researchers understand what happens to women and offspring after this vaccine exposure.
Swiftwater, PennsylvaniaAges Any age - NCT05761197Recruiting
Study of mouth yeast infection and a preventive treatment
This trial studies children ages 9–15 months and looks at oropharyngeal yeast infection in the mouth (often called “OPC”). It may help researchers understand how to prevent or manage this condition.
Philadelphia, PennsylvaniaAges 9 months–1.3 years - NCT05711667RecruitingPhase 3
Letermovir to prevent CMV after stem cell transplant in kids
This trial tests whether the medicine letermovir can prevent a common virus (CMV) from coming back after an allogeneic stem cell transplant in children. It may help lower the risk of CMV infection during the vulnerable period right after transplant.
Hershey, PennsylvaniaAges 2–18
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting infections studies listed above.
- Children's Hospital of Philadelphia · 5 studies
- University of Pittsburgh Medical Center · 5 studies
- University of Pennsylvania · 3 studies
- Children's Hospital of Pennsylvania · 2 studies
- Children's Hospital of Pittsburgh of UPMC
- Einstein Medical Center
- Geisinger 65-Forward, Buckhorn
- Geisinger Medical Center
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in Pennsylvania?
- Yes. We're currently tracking 86 recruiting infections studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.