Clinical trials · Pennsylvania
Infections clinical trials in Pennsylvania
We’re tracking 86 recruiting infections studies with a site in Pennsylvania — including Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06237452RecruitingPhase 3
VE303 to prevent repeat C. diff infections
This trial tests a new medicine called VE303, a live bacterial therapy, to prevent C. diff infections from coming back. It is for people who have had C. diff at least once in the last 6 months, or who are at high risk for a repeat infection due to age or other health problems.
Harrisburg, PennsylvaniaAges 12 years+ - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Hershey, PennsylvaniaAges 18 years+ - NCT07859852Recruiting
Blood test for bloodstream infections
This study tests a new blood test that may find bloodstream infections faster and more accurately than standard methods. It could help doctors start the right treatment sooner.
Danville, PennsylvaniaAges Any age - NCT07214311RecruitingPhase 2/Phase 3
Preventing repeat knee infection after joint-saving surgery
This trial tests a new medicine called PLG0206 to help prevent a knee infection from coming back after a procedure to clean the joint while keeping the artificial knee in place. If you qualify, you'll receive the study medicine or a placebo along with standard antibiotics.
Pittsburgh, PennsylvaniaAges 18–85 - NCT05172089Recruiting
Treating recurring infection in diabetic foot ulcers
This trial studies an approach to treat bacteria living in a diabetic foot ulcer and help prevent the ulcer from coming back. You may be able to join if you have an open diabetic foot ulcer and good blood flow to the wound.
Cranberry Township, PennsylvaniaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Hershey, PennsylvaniaAges birth–20 years - NCT07513285RecruitingPhase 2
Ibezapolstat pill for recurrent C. difficile infection
This trial tests a new oral antibiotic called ibezapolstat to treat recurrent C. difficile infection (CDI)—a serious diarrheal illness caused by bacteria in your gut. The study focuses on patients who have had multiple CDI episodes and may benefit from a different treatment approach.
Pittsburgh, PennsylvaniaAges 18–90 - NCT04723940Enrolling by invitationPhase 3
Oral vs intravenous antibiotics for joint infection
This trial compares taking antibiotics by mouth versus through an IV line for people who have an infection in their hip or knee replacement. The goal is to see if oral antibiotics work just as well as IV antibiotics after surgery to clean the infection.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03827694Recruiting
Testing a noninvasive scan for serious lung mold infections in kids
This study uses noninvasive breathing/relates imaging (MRI or CT) to help diagnose mold infections in the lungs in children and young adults. It may help doctors find these infections sooner, especially in people with weakened immune systems.
Philadelphia, PennsylvaniaAges 4 months–21 years - NCT07599865RecruitingPhase 2
Bubble study for knee infection after joint replacement
This trial tests if a contrast agent used in ultrasound can help surgeons see pockets of infection around knee implants during revision surgery. It may help doctors do a better job cleaning out the infection.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07387367RecruitingPhase 3
Comparing two drugs for adenovirus after stem cell transplant
This trial tests a new drug, brincidofovir (BCV), against an existing drug, cidofovir (CDV), for treating adenovirus infection in people who recently had a stem cell transplant. The goal is to see which works better with fewer side effects.
Pittsburgh, PennsylvaniaAges 2 months+ - NCT07322146Enrolling by invitationPhase 4
Shorter antibiotics for children with common infections
This study tests whether shorter courses of antibiotics are as effective as longer ones for children hospitalized with pneumonia, skin infections, or urinary tract infections. It may help children get back to normal faster and reduce side effects.
Pittsburgh, PennsylvaniaAges 2 months–17 years - NCT07285213RecruitingPhase 2
Preventing C. diff return with an antibody
This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07275905RecruitingPhase 1
Phage therapy for chronic achromobacter lung infection in cystic fibrosis
This study tests whether giving you a mixture of viruses (called phages) that specifically target the bacteria Achromobacter can help treat your chronic lung infection. You would breathe in the phages, and the study will check if this is safe and helps improve your breathing.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07009548Enrolling by invitationPhase 4
CytoGam for CMV in solid organ transplant recipients
This trial tests whether adding CytoGam (an antibody treatment) to standard antiviral therapy can better treat CMV (a common virus) in people who have received a solid organ transplant. It may help those with high virus levels or a new infection after transplant.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06925321RecruitingPhase 3
Testing Fosmanogepix for Serious Mold Infections
This trial tests a new drug, Fosmanogepix, for treating serious mold infections that are hard to treat with current medicines. It may be an option for people with limited treatment choices.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Philadelphia, PennsylvaniaAges 40–60 - NCT06822426RecruitingPhase 3
Catheter lock solution to prevent bloodstream infections in patients on IV nutrition
This study tests a catheter lock solution called DefenCath (taurolidine and heparin) against a standard heparin lock to see if it reduces central line bloodstream infections in people receiving IV nutrition (total parenteral nutrition) for more than 3 months.
Philadelphia, PennsylvaniaAges 12 years+ - NCT06774144Enrolling by invitationPhase 3
Rezafungin to prevent fungal infections in liver transplant patients
This trial tests whether a medicine called rezafungin can help prevent serious fungal infections in people who have received a liver transplant. If you have certain risk factors, this study may offer extra protection against infections.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06746883Recruiting
Safety study of an antibiotic for ABC infection
This study checks how safe sulbactam-durlobactam (a combination antibiotic) is in adults with a serious infection caused by ABC bacteria, especially looking for allergic reactions. If you are already getting this antibiotic as part of your care, you may be able to join.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06738407RecruitingPhase 4
Doxycycline to prevent STIs in high-risk people
This study tests whether taking a daily antibiotic (doxycycline) can prevent sexually transmitted infections in people at high risk. If you've had an STI recently and sometimes have sex without condoms, you might be able to join.
Philadelphia, PennsylvaniaAges 13–29 - NCT03266653RecruitingPhase 2
T-cell therapy for stubborn Epstein-Barr virus after transplants
This trial tests an immune therapy made from EBV-targeted T-cells to treat EBV infections that do not improve with standard anti-viral medicines. It may help by strengthening the body’s ability to fight EBV after certain transplants or immune problems.
Philadelphia, PennsylvaniaAges 1 month–79 years - NCT06472765Enrolling by invitation
Study of the Vaginal Ecosystem in Healthy Women
This study looks at the natural balance of bacteria and other factors in the vagina of healthy women. It aims to learn more about what a healthy vaginal ecosystem looks like.
Bryn Mawr, PennsylvaniaAges 18–89 - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Pittsburgh, PennsylvaniaAges 6 years+
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting infections studies listed above.
- Children's Hospital of Philadelphia · 3 studies
- University of Pittsburgh · 2 studies
- UPMC Presbyterian Hospital · 2 studies
- 6201 Penn Therapeutics CRS
- Center for Pelvic Medicine
- Children's Hospital of Pennsylvania
- Clinical Trial Site
- Frontier Clinical Research
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in Pennsylvania?
- Yes. We're currently tracking 86 recruiting infections studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.