Clinical trials · Illinois
Infections clinical trials in Illinois
We’re tracking 62 recruiting infections studies with a site in Illinois — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT06237452RecruitingPhase 3
VE303 to prevent repeat C. diff infections
This trial tests a new medicine called VE303, a live bacterial therapy, to prevent C. diff infections from coming back. It is for people who have had C. diff at least once in the last 6 months, or who are at high risk for a repeat infection due to age or other health problems.
Burr Ridge, IllinoisAges 12 years+ - NCT07095361RecruitingPhase 4
Daily enzyme therapy for infected pleural fluid
This trial tests a once-daily enzyme treatment given through a chest tube to clear infected fluid from around the lungs. It may help people with complicated pneumonia or empyema who still have fluid buildup after initial drainage.
Chicago, IllinoisAges 18 years+ - NCT06293352Recruiting
Comparing two antibiotic spacers for knee infection
This trial compares two types of antibiotic spacers for people with a long-term knee replacement infection. It tests whether a spacer made entirely of antibiotic cement or one with a metal core works better to treat the infection before a new knee replacement.
Chicago, IllinoisAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Chicago, IllinoisAges birth–20 years - NCT07513285RecruitingPhase 2
Ibezapolstat pill for recurrent C. difficile infection
This trial tests a new oral antibiotic called ibezapolstat to treat recurrent C. difficile infection (CDI)—a serious diarrheal illness caused by bacteria in your gut. The study focuses on patients who have had multiple CDI episodes and may benefit from a different treatment approach.
Skokie, IllinoisAges 18–90 - NCT03827694Recruiting
Testing a noninvasive scan for serious lung mold infections in kids
This study uses noninvasive breathing/relates imaging (MRI or CT) to help diagnose mold infections in the lungs in children and young adults. It may help doctors find these infections sooner, especially in people with weakened immune systems.
Chicago, IllinoisAges 4 months–21 years - NCT07387367RecruitingPhase 3
Comparing two drugs for adenovirus after stem cell transplant
This trial tests a new drug, brincidofovir (BCV), against an existing drug, cidofovir (CDV), for treating adenovirus infection in people who recently had a stem cell transplant. The goal is to see which works better with fewer side effects.
Chicago, IllinoisAges 2 months+ - NCT07285213RecruitingPhase 2
Preventing C. diff return with an antibody
This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.
Burr Ridge, IllinoisAges 18 years+ - NCT06925321RecruitingPhase 3
Testing Fosmanogepix for Serious Mold Infections
This trial tests a new drug, Fosmanogepix, for treating serious mold infections that are hard to treat with current medicines. It may be an option for people with limited treatment choices.
Chicago, IllinoisAges 18 years+ - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Chicago, IllinoisAges 40–60 - NCT06822426RecruitingPhase 3
Catheter lock solution to prevent bloodstream infections in patients on IV nutrition
This study tests a catheter lock solution called DefenCath (taurolidine and heparin) against a standard heparin lock to see if it reduces central line bloodstream infections in people receiving IV nutrition (total parenteral nutrition) for more than 3 months.
Maywood, IllinoisAges 12 years+ - NCT06794541RecruitingPhase 2
Testing eravacycline for kids with serious belly infections
This trial tests an antibiotic called eravacycline for children (ages 8–17) with serious belly infections. The medicine is given through an IV in the hospital to see if it is safe and tolerable.
Chicago, IllinoisAges 8–17 - NCT06738407RecruitingPhase 4
Doxycycline to prevent STIs in high-risk people
This study tests whether taking a daily antibiotic (doxycycline) can prevent sexually transmitted infections in people at high risk. If you've had an STI recently and sometimes have sex without condoms, you might be able to join.
Chicago, IllinoisAges 13–29 - NCT06631287RecruitingPhase 3
Testing baricitinib for persistent long COVID symptoms
This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.
Chicago, IllinoisAges 18 years+ - NCT04474132Recruiting
Testing for current or past Toxoplasmosis infection
This study checks whether a simple “point-of-care” test can detect current or past Toxoplasmosis infection (a common germ). Your results may help evaluate how well the test works and how it could be used in care.
Chicago, IllinoisAges 18–90 - NCT06034080Recruiting
Cutting down unneeded antibiotics for children's ear infections
This study tests ways to help doctors avoid prescribing antibiotics when they are not needed for children with ear infections. If you are a parent of a child diagnosed with an ear infection or a healthcare provider, you may be able to join different parts of the study.
Chicago, IllinoisAges 6 months–17 years - NCT06395636Recruiting
Fitbit to detect infections after children's appendix surgery
This trial uses a Fitbit wearable to see if it can help detect infections early in children recovering from surgery for complicated appendicitis. It aims to improve recovery and catch problems sooner.
Chicago, IllinoisAges 3–18 - NCT06266416Recruiting
Black caregivers & girls empowerment study
This study tests a program called IMARA to support black male caregivers and the girls they care for. It aims to improve family relationships and reduce risky behaviors in girls.
Chicago, IllinoisAges 13 years+ - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Chicago, IllinoisAges 6 years+ - NCT05550298Recruiting
Study of virus infections after pediatric transplants
This study looks at how respiratory viruses behave and how the body responds in children who are about to receive, or have recently received, a transplant. It may help doctors better diagnose and treat viral infections in transplant patients by studying blood samples and test results.
Chicago, IllinoisAges Up to 18 years - NCT05947071RecruitingPhase 2
Higher-dose flu vaccine versus standard dose in child transplant patients
This trial compares a higher-dose flu vaccine to the standard dose in children who recently received a kidney, heart, and/or liver transplant. It aims to see which dose better protects children against influenza while checking for safety.
Chicago, IllinoisAges 3–17 - NCT05719441RecruitingPhase 2
Testing HIV antibodies plus early HIV treatment for possible remission
This trial tests whether giving two powerful HIV-fighting antibodies (called broadly neutralizing monoclonal antibodies) along with starting standard HIV medications soon after infection can help control the virus without needing daily pills. If successful, it might allow people to take a 'treatment pause' while keeping their immune system healthy.
Chicago, IllinoisAges 18–70 - NCT05624450RecruitingPhase 3
Test drug tozorakimab for hospitalized viral lung infection needing oxygen
This Phase 3 study tests tozorakimab to see if it helps people hospitalized with a viral lung infection that is causing low oxygen levels. You might qualify if you still need supplemental oxygen when the study starts.
Chicago, IllinoisAges 18 years+ - NCT05471973Recruiting
Study for suspected heart device infection care improvement
This study is testing an approach to improve how clinicians care for people with suspected infections around an implanted heart device (like a pacemaker or defibrillator). It may help ensure the infection is recognized and treated appropriately, especially when device removal (extraction) might be needed.
Chicago, IllinoisAges 18 years+
Infections trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting infections studies listed above.
- Northwestern University · 4 studies
- Ann & Robert H. Lurie Children's Hospital of Chicago · 2 studies
- Loyola University Medical Center · 2 studies
- Research Site · 2 studies
- University of Chicago · 2 studies
- AllianceChicago
- Ann and Robert H Lurie Children's Hospital
- Ann and Robert H Lurie Children's Hospital of Chicago
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in Illinois?
- Yes. We're currently tracking 62 recruiting infections studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.