Clinical trials · California
Infections clinical trials in California
We’re tracking 156 recruiting infections studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06237452RecruitingPhase 3
VE303 to prevent repeat C. diff infections
This trial tests a new medicine called VE303, a live bacterial therapy, to prevent C. diff infections from coming back. It is for people who have had C. diff at least once in the last 6 months, or who are at high risk for a repeat infection due to age or other health problems.
Apple Valley, CaliforniaAges 12 years+ - NCT07110636Recruiting
Blood test for infection in immunocompromised adults
This trial tests a blood test that looks for infection by analyzing tiny bits of DNA from microbes. It may help find infections faster in people with weakened immune systems, such as transplant recipients or those with blood cancers.
San Francisco, CaliforniaAges 18 years+ - NCT06824350Recruiting
Chlorine in water to prevent newborn infections
This trial tests whether adding a small amount of chlorine to the drinking water at public health facilities can reduce infections (including those resistant to antibiotics) in newborns. You and your baby may be eligible if you deliver at a participating facility that does not already chlorinate its water.
Berkeley, CaliforniaAges Any age - NCT07095361RecruitingPhase 4
Daily enzyme therapy for infected pleural fluid
This trial tests a once-daily enzyme treatment given through a chest tube to clear infected fluid from around the lungs. It may help people with complicated pneumonia or empyema who still have fluid buildup after initial drainage.
Palo Alto, CaliforniaAges 18 years+ - NCT07859852Recruiting
Blood test for bloodstream infections
This study tests a new blood test that may find bloodstream infections faster and more accurately than standard methods. It could help doctors start the right treatment sooner.
Orange, CaliforniaAges Any age - NCT07379684RecruitingPhase 1
Amicidin-β for infected surgical or traumatic wounds
This trial tests a topical solution called Amicidin-β for people with infected surgical or traumatic wounds. It may help treat the infection without needing strong oral or IV antibiotics.
Torrance, CaliforniaAges 18–79 - NCT07221370RecruitingPhase 2/Phase 3
Vancomycin to prevent C. diff infection in ICU patients
This trial tests whether giving vancomycin through a tube into the stomach can prevent a serious gut infection called C. diff in people who are very sick in the ICU and taking antibiotics. If you qualify, you might receive this medicine to lower your risk.
Moreno Valley, CaliforniaAges 18 years+ - NCT07108660Recruiting
Predicting and reducing bloodstream infections from central lines
This trial uses machine learning to predict infections that can happen with central lines (special IVs placed in large veins) and aims to reduce how often they occur. It focuses on hospitals with the highest infection rates, so you might be eligible if you receive care at one of these hospitals.
Apple Valley, CaliforniaAges 18 years+ - NCT07089836Recruiting
Syphilis blood test study for at-risk and healthy people
This study tests two new blood tests for syphilis. It compares them to approved tests using blood from people who may have or had syphilis, including pregnant women, HIV-positive people, and healthy volunteers.
Lancaster, CaliforniaAges 13 years+ - NCT06909110RecruitingPhase 1/Phase 2
Immune cells for viral infections after transplant
This trial tests a treatment using specially trained immune cells (virus-specific T-cells) to fight stubborn infections with adenovirus, CMV, or EBV in people with weakened immune systems, such as after a stem cell or organ transplant.
Palo Alto, CaliforniaAges 1 month–65 years - NCT05645107RecruitingPhase 3
XEMBIFY plus usual care to prevent infections
This Phase 3 study tests whether XEMBIFY (an immune protein therapy) plus standard medical treatment can better prevent serious or repeated infections. It is for people with certain cancers of blood/immune systems who are already having trouble with infections.
Huntington Park, CaliforniaAges 18 years+ - NCT05603650Recruiting
Mouthwash study for healthy bacteria in your mouth and gut
This study tests how a mouthrinse changes the helpful bacteria in your mouth and stomach/gut. You may need several visits and phone follow-ups to see how your microbiome shifts over time.
Irvine, CaliforniaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Los Angeles, CaliforniaAges birth–20 years - NCT03827694Recruiting
Testing a noninvasive scan for serious lung mold infections in kids
This study uses noninvasive breathing/relates imaging (MRI or CT) to help diagnose mold infections in the lungs in children and young adults. It may help doctors find these infections sooner, especially in people with weakened immune systems.
La Jolla, CaliforniaAges 4 months–21 years - NCT05985642Recruiting
HIV treatment interruption study for long-term participants
This study looks at people with HIV who have already taken a break from their HIV medications (called an analytic treatment interruption, or ATI) as part of another study. It aims to understand how well the body can control the virus during longer breaks from treatment, up to 96 weeks.
San Francisco, CaliforniaAges 18 years+ - NCT07513285RecruitingPhase 2
Ibezapolstat pill for recurrent C. difficile infection
This trial tests a new oral antibiotic called ibezapolstat to treat recurrent C. difficile infection (CDI)—a serious diarrheal illness caused by bacteria in your gut. The study focuses on patients who have had multiple CDI episodes and may benefit from a different treatment approach.
Sacramento, CaliforniaAges 18–90 - NCT07499544RecruitingPhase 3
Testing Libevitug for chronic hepatitis D
This study tests a new drug, Libevitug, for people with chronic hepatitis D (HDV). It aims to see if the drug can help control the virus and improve liver health.
Garden Grove, CaliforniaAges 12–70 - NCT07435649Recruiting
New test for finding germs in spinal fluid during brain infections
This study tests a new type of test called Delve Detect that looks for germs in spinal fluid from people suspected of having a brain or spinal cord infection. It helps doctors find the cause faster and more accurately.
San Francisco, CaliforniaAges Any age - NCT07387367RecruitingPhase 3
Comparing two drugs for adenovirus after stem cell transplant
This trial tests a new drug, brincidofovir (BCV), against an existing drug, cidofovir (CDV), for treating adenovirus infection in people who recently had a stem cell transplant. The goal is to see which works better with fewer side effects.
Sacramento, CaliforniaAges 2 months+ - NCT07285213RecruitingPhase 2
Preventing C. diff return with an antibody
This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.
Chula Vista, CaliforniaAges 18 years+ - NCT07087145Recruiting
HPV test by mail for men with HIV
This trial explores if mailing an HPV self-test kit to your home is a good way to screen for HPV. It's for men over 35 who have sex with men, including trans women, and are living with HIV.
San Francisco, CaliforniaAges 35 years+ - NCT07024641RecruitingPhase 1
Safety study of GIGA-2339 for chronic Hepatitis B
This study tests an experimental antibody (GIGA-2339) given as an infusion to people with chronic Hepatitis B. It aims to see if the drug is safe and how the body processes it, possibly helping to control the virus.
Huntington Beach, CaliforniaAges 18 years+ - NCT06998043RecruitingPhase 2
Phage therapy for cystic fibrosis with pseudomonas lung infection
This trial tests a new treatment using phages (viruses that kill bacteria) for people with cystic fibrosis who have a chronic pseudomonas lung infection. It aims to see if adding phages to your usual care can help control the infection.
Palo Alto, CaliforniaAges 18 years+ - NCT06925321RecruitingPhase 3
Testing Fosmanogepix for Serious Mold Infections
This trial tests a new drug, Fosmanogepix, for treating serious mold infections that are hard to treat with current medicines. It may be an option for people with limited treatment choices.
Los Angeles, CaliforniaAges 18 years+
Infections trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting infections studies listed above.
- University of California, Davis · 3 studies
- University of California, San Francisco · 3 studies
- City of Hope · 2 studies
- Lucile Packard Children's Hospital Stanford · 2 studies
- Beckman Laser Institute and Medical Clinic
- Chemidox Clinical Trials California
- Children's Hospital of Los Angeles
- Children's Hospital of Orange County
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in California?
- Yes. We're currently tracking 156 recruiting infections studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.