Clinical trials · Maryland
Infections clinical trials in Maryland
We’re tracking 108 recruiting infections studies with a site in Maryland — including Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT06237452RecruitingPhase 3
VE303 to prevent repeat C. diff infections
This trial tests a new medicine called VE303, a live bacterial therapy, to prevent C. diff infections from coming back. It is for people who have had C. diff at least once in the last 6 months, or who are at high risk for a repeat infection due to age or other health problems.
Chevy Chase, MarylandAges 12 years+ - NCT07215871Enrolling by invitationPhase 1
Second H10N7 flu challenge for prior participants
This study tests whether people who have already been exposed to a lab-made H10N7 flu virus can be safely exposed again. It checks how their immune system responds and how long they shed the virus, in a controlled, isolated setting.
Bethesda, MarylandAges 18–55 - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Baltimore, MarylandAges 18 years+ - NCT07859852Recruiting
Blood test for bloodstream infections
This study tests a new blood test that may find bloodstream infections faster and more accurately than standard methods. It could help doctors start the right treatment sooner.
Baltimore, MarylandAges Any age - NCT07379684RecruitingPhase 1
Amicidin-β for infected surgical or traumatic wounds
This trial tests a topical solution called Amicidin-β for people with infected surgical or traumatic wounds. It may help treat the infection without needing strong oral or IV antibiotics.
Baltimore, MarylandAges 18–79 - NCT07214311RecruitingPhase 2/Phase 3
Preventing repeat knee infection after joint-saving surgery
This trial tests a new medicine called PLG0206 to help prevent a knee infection from coming back after a procedure to clean the joint while keeping the artificial knee in place. If you qualify, you'll receive the study medicine or a placebo along with standard antibiotics.
Baltimore, MarylandAges 18–85 - NCT05645107RecruitingPhase 3
XEMBIFY plus usual care to prevent infections
This Phase 3 study tests whether XEMBIFY (an immune protein therapy) plus standard medical treatment can better prevent serious or repeated infections. It is for people with certain cancers of blood/immune systems who are already having trouble with infections.
Bethesda, MarylandAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Baltimore, MarylandAges birth–20 years - NCT06341543Recruiting
CMV blood test to guide treatment after organ transplant
This study uses a blood test (QuantiFERON-CMV) to help decide whether people with a silent (no symptoms) CMV infection after a solid organ transplant need treatment. If you have a low-to-moderate level of CMV in your blood without fever or organ issues, this trial may help your doctor choose the safest approach.
Grenoble, MarylandAges 18 years+ - NCT07435649Recruiting
New test for finding germs in spinal fluid during brain infections
This study tests a new type of test called Delve Detect that looks for germs in spinal fluid from people suspected of having a brain or spinal cord infection. It helps doctors find the cause faster and more accurately.
Baltimore, MarylandAges Any age - NCT07285213RecruitingPhase 2
Preventing C. diff return with an antibody
This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.
Glen Burnie, MarylandAges 18 years+ - NCT07222670RecruitingPhase 2
Nasal spray to prevent respiratory infections in healthy adults
This trial tests a nasal spray, INNA-051, that may help your nose and airways fight off viruses that cause respiratory infections like colds and flu. It is for healthy adults aged 18-45 who are around many people and may be exposed to germs.
Baltimore, MarylandAges 18–45 - NCT07024641RecruitingPhase 1
Safety study of GIGA-2339 for chronic Hepatitis B
This study tests an experimental antibody (GIGA-2339) given as an infusion to people with chronic Hepatitis B. It aims to see if the drug is safe and how the body processes it, possibly helping to control the virus.
Baltimore, MarylandAges 18 years+ - NCT06925321RecruitingPhase 3
Testing Fosmanogepix for Serious Mold Infections
This trial tests a new drug, Fosmanogepix, for treating serious mold infections that are hard to treat with current medicines. It may be an option for people with limited treatment choices.
Baltimore, MarylandAges 18 years+ - NCT06908096RecruitingPhase 1
EBV nanoparticle vaccine study for healthy adults
This study tests two experimental vaccines against Epstein-Barr virus (EBV), the germ that causes mono. You may be able to join if you are a healthy adult aged 18–29 and haven't had an EBV vaccine before. The trial will check if the vaccines are safe and trigger an immune response.
Bethesda, MarylandAges 18–29 - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Baltimore, MarylandAges 40–60 - NCT06822426RecruitingPhase 3
Catheter lock solution to prevent bloodstream infections in patients on IV nutrition
This study tests a catheter lock solution called DefenCath (taurolidine and heparin) against a standard heparin lock to see if it reduces central line bloodstream infections in people receiving IV nutrition (total parenteral nutrition) for more than 3 months.
Baltimore, MarylandAges 12 years+ - NCT06805994RecruitingPhase 1
Restoring infant nose bacteria after staph treatment
This study tests whether giving a nasal spray of healthy bacteria to infants can restore good germs in the nose after they receive mupirocin ointment to treat Staph aureus. It aims to bring back a healthy nasal microbiome.
Baltimore, MarylandAges birth–60 years - NCT06738407RecruitingPhase 4
Doxycycline to prevent STIs in high-risk people
This study tests whether taking a daily antibiotic (doxycycline) can prevent sexually transmitted infections in people at high risk. If you've had an STI recently and sometimes have sex without condoms, you might be able to join.
Baltimore, MarylandAges 13–29 - NCT03266653RecruitingPhase 2
T-cell therapy for stubborn Epstein-Barr virus after transplants
This trial tests an immune therapy made from EBV-targeted T-cells to treat EBV infections that do not improve with standard anti-viral medicines. It may help by strengthening the body’s ability to fight EBV after certain transplants or immune problems.
Baltimore, MarylandAges 1 month–79 years - NCT06472765Enrolling by invitation
Study of the Vaginal Ecosystem in Healthy Women
This study looks at the natural balance of bacteria and other factors in the vagina of healthy women. It aims to learn more about what a healthy vaginal ecosystem looks like.
Bethesda, MarylandAges 18–89 - NCT06337292RecruitingPhase 3
Wound vacuum therapy for high-risk leg fractures
This trial tests if a special wound vacuum (negative pressure therapy) applied after surgery can lower the risk of infections and other complications in people with severe leg fractures. If you have a high-risk tibia or ankle fracture, this treatment may help you heal better.
Baltimore, MarylandAges 18 years+ - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Baltimore, MarylandAges 6 years+ - NCT05706116RecruitingPhase 1
Study gives worm eggs by mouth to healthy adults
This Phase 1 trial tests how safe and tolerated orally taken Trichuris trichiura (a type of intestinal worm) eggs are in healthy adults. It aims to help researchers understand early safety and study setup before any future treatments.
Bethesda, MarylandAges 18–45
Infections trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting infections studies listed above.
- Johns Hopkins University · 6 studies
- National Institutes of Health Clinical Center · 2 studies
- 201 Johns Hopkins University CRS
- Center for Vaccine Development and Global Health (CVD)
- CHU Grenoble Alpes
- Clinical Trial Site
- Dr. Christina Enzmann at Easton Advanced Aesthetics and Regenerative Medicine
- GC2202 Study Site 111
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in Maryland?
- Yes. We're currently tracking 108 recruiting infections studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.