Clinical trials · Maryland
Infections clinical trials in Maryland
We’re tracking 108 recruiting infections studies with a site in Maryland — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT06237452RecruitingPhase 3
VE303 to prevent repeat C. diff infections
This trial tests a new medicine called VE303, a live bacterial therapy, to prevent C. diff infections from coming back. It is for people who have had C. diff at least once in the last 6 months, or who are at high risk for a repeat infection due to age or other health problems.
Baltimore, MarylandAges 12 years+ - NCT07215871Enrolling by invitationPhase 1
Second H10N7 flu challenge for prior participants
This study tests whether people who have already been exposed to a lab-made H10N7 flu virus can be safely exposed again. It checks how their immune system responds and how long they shed the virus, in a controlled, isolated setting.
Bethesda, MarylandAges 18–55 - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Baltimore, MarylandAges 18 years+ - NCT07214311RecruitingPhase 2/Phase 3
A trial of PLG0206 to prevent knee joint infection after surgery
This trial tests if a new drug called PLG0206 can stop a knee joint infection from coming back after a surgery called DAIR. DAIR cleans the infected area and keeps the artificial knee in place, and this study wants to see if adding PLG0206 helps prevent the infection from returning.
Baltimore, MarylandAges 18–80 - NCT05645107RecruitingPhase 3
XEMBIFY plus usual care to prevent infections
This Phase 3 study tests whether XEMBIFY (an immune protein therapy) plus standard medical treatment can better prevent serious or repeated infections. It is for people with certain cancers of blood/immune systems who are already having trouble with infections.
Bethesda, MarylandAges 18 years+ - NCT07379684RecruitingPhase 1
Amicidin-β for infected surgical or traumatic wounds
This trial tests a topical solution called Amicidin-β for people with infected surgical or traumatic wounds. It may help treat the infection without needing strong oral or IV antibiotics.
Baltimore, MarylandAges 18–79 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Baltimore, MarylandAges birth–20 years - NCT05592626RecruitingPhase 1/Phase 2
T cell activator STAR0602 for advanced solid tumors
This study tests an experimental drug called STAR0602 that aims to boost your immune system's T cells to fight advanced solid tumors. It's for patients whose cancer has not responded to standard treatments or for whom such treatments are not suitable.
Bethesda, MarylandAges 18 years+ - NCT06822426RecruitingPhase 3
Preventing infections in central lines for people on IV nutrition
This trial tests a new catheter lock solution (DefenCath) to prevent infections in people who need long-term IV nutrition through a central line. It compares the study drug to a standard heparin lock, and you'll be randomly assigned to one group.
Baltimore, MarylandAges 18 years+ - NCT05361941Recruiting
Antibiotic graft to help bone regrow in infected knee surgery areas
This trial tests an antibiotic “graft” placed into or near infected bone cavities around a knee replacement (TKA) to help new bone grow. You may be considered if you have an infected knee implant area and can safely take part in follow-up visits and treatment.
Baltimore, MarylandAges 22 years+ - NCT05719441RecruitingPhase 2
Antibodies plus early HIV treatment to try for HIV remission
This study tests whether giving special HIV-fighting antibodies along with starting standard HIV medicine soon after infection can help you reach “HIV remission.” It may reduce or delay the return of detectable virus, but you must be willing to follow close monitoring and specific study steps.
Baltimore, MarylandAges 18–70 - NCT07222670RecruitingPhase 2
Study of INNA-051 to prevent viral respiratory illness in healthy adults
This trial tests whether INNA-051 can help prevent respiratory infections caused by viruses in healthy adults aged 18 to 45. It may be an option if you are at higher risk of catching such infections due to your living or work situation.
Baltimore, MarylandAges 18–45 - NCT04419870Recruiting
Studying infections and immune responses in mitochondrial disease
This study looks at what happens in the body when someone with mitochondrial disease gets a sudden (acute) infection, and how the immune system and metabolism respond. Results may help doctors better recognize and manage infections in people with mitochondrial disease.
Bethesda, MarylandAges 2 months–115 years - NCT05624450RecruitingPhase 3
Test drug tozorakimab for hospitalized viral lung infection needing oxygen
This Phase 3 study tests tozorakimab to see if it helps people hospitalized with a viral lung infection that is causing low oxygen levels. You might qualify if you still need supplemental oxygen when the study starts.
Annapolis, MarylandAges 18 years+ - NCT07024641RecruitingPhase 1
Safety study of GIGA-2339 for chronic Hepatitis B
This study tests an experimental antibody (GIGA-2339) given as an infusion to people with chronic Hepatitis B. It aims to see if the drug is safe and how the body processes it, possibly helping to control the virus.
Baltimore, MarylandAges 18 years+ - NCT06925321RecruitingPhase 3
Testing Fosmanogepix for Serious Mold Infections
This trial tests a new drug, Fosmanogepix, for treating serious mold infections that are hard to treat with current medicines. It may be an option for people with limited treatment choices.
Baltimore, MarylandAges 18 years+ - NCT03266653RecruitingPhase 2
T-cell therapy for stubborn Epstein-Barr virus after transplants
This trial tests an immune therapy made from EBV-targeted T-cells to treat EBV infections that do not improve with standard anti-viral medicines. It may help by strengthening the body’s ability to fight EBV after certain transplants or immune problems.
Baltimore, MarylandAges 1 month–79 years - NCT03808922RecruitingPhase 3
DAS181 treatment for COVID-19 lung infection in immune-compromised adults
This Phase 3 trial tests DAS181 to treat lower lung (chest) viral infections in people with weakened immune systems, including a COVID-19 subgroup. It may help by targeting certain viruses in the lungs, but joining depends on your oxygen needs, recent diagnosis, and other safety factors.
Baltimore, MarylandAges Any age - NCT07285213RecruitingPhase 2
Preventing C. diff return with an antibody
This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.
Glen Burnie, MarylandAges 18 years+ - NCT04197596RecruitingPhase 1/Phase 2
BK infection immune-cell treatment after transplant or weak immunity
This Phase 1/2 study tests lab-made immune cells that specifically target BK virus in people whose BK infection keeps coming back or doesn’t improve. It may help by boosting the body’s ability to clear the virus, especially when standard antiviral treatments don’t work or can’t be tolerated.
Baltimore, MarylandAges 1 month–79 years - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Hyattsville, MarylandAges 18 years+ - NCT05141058RecruitingPhase 1
T cell therapy to help prevent COVID-19 after transplant
This Phase 1 trial tests a donated immune-cell treatment (T cells) to help immunocompromised people fight or resist COVID-19 after they recently received a bone marrow or stem cell transplant. It aims to see if the treatment is safe and if it helps the body respond better to the virus.
Baltimore, MarylandAges 2–80 - NCT05706116RecruitingPhase 1
Study gives worm eggs by mouth to healthy adults
This Phase 1 trial tests how safe and tolerated orally taken Trichuris trichiura (a type of intestinal worm) eggs are in healthy adults. It aims to help researchers understand early safety and study setup before any future treatments.
Bethesda, MarylandAges 18–45 - NCT06337292RecruitingPhase 3
Wound vacuum therapy for high-risk leg fractures
This trial tests if a special wound vacuum (negative pressure therapy) applied after surgery can lower the risk of infections and other complications in people with severe leg fractures. If you have a high-risk tibia or ankle fracture, this treatment may help you heal better.
Baltimore, MarylandAges 18 years+
Infections trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting infections studies listed above.
- Johns Hopkins University · 5 studies
- National Institutes of Health Clinical Center · 4 studies
- Johns Hopkins Hospital · 3 studies
- Research Site · 2 studies
- Sinai Hospital of Baltimore · 2 studies
- University of Maryland Medical System · 2 studies
- Akero Clinical Study Site
- Center for Vaccine Development and Global Health
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in Maryland?
- Yes. We're currently tracking 108 recruiting infections studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.