Clinical trials
Insomnia clinical trials
Below are recruiting insomnia clinical trials, each written for real people, not researchers. We’re tracking 251 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05125146Recruiting
Internet CBT for insomnia versus medicines
This study compares an online form of CBT (a structured therapy for sleep) with sleep medicines for adults with insomnia. It may help you see which approach improves how easily you fall asleep and stay asleep.
Kingston, OntarioAges 18 years+ - NCT05301543Recruiting
Program to improve long-term insomnia symptoms
This study tests a behavioral (non-medication) program to help people with chronic insomnia sleep better. It may help if you regularly use sleep medications but still struggle with staying asleep or falling asleep.
Philadelphia, PennsylvaniaAges 55–85 - NCT05390918Recruiting
Trial for teen sleep and suicidal thoughts risk
This study aims to see if treating insomnia (sleep problems) can lower overall risk related to suicidal behavior in teens. You may be eligible if you’ve had both recent sleep issues and recent suicidal thoughts, with some important safety exclusions.
Columbus, OhioAges 11–18 - NCT05402761Recruiting
Nurse-guided sleep program for insomnia after brain injury
This trial studies whether nurse-guided behavioral sleep therapy can improve insomnia in people recovering after a traumatic brain injury (TBI). It may help you sleep better by targeting sleep habits and insomnia symptoms.
TaipeiAges 20–65 - NCT05441280RecruitingPhase 2
Pimavanserin to improve sleep in veterans with PTSD
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Houston, TexasAges 18–64 - NCT05499741Recruiting
Heat-based therapy to improve sleep in adults with Tourette’s
This trial tests a forehead temperature-regulating therapy to help improve insomnia symptoms in adults who have Tourette’s (and significant tics). It may help you sleep better by testing whether changing forehead temperature can improve sleep quality and efficiency.
Los Angeles, CaliforniaAges 18–50 - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+ - NCT05618002Recruiting
Study compares sleep medicines for chronic pain insomnia
This trial tests different treatments to help people with long-term (chronic) pain and severe insomnia sleep better. It’s looking at three options—one medicine (lemborexant) compared with existing sleep medicines (zopiclone and clonidine)—and whether they improve sleep when non-medicine sleep strategies haven’t worked.
Surrey, British ColumbiaAges 20–99 - NCT05683145Recruiting
Better sleep for people with moderate or severe TBI
This trial studies an approach to improve insomnia (trouble falling or staying asleep) in people who had a moderate-to-severe traumatic brain injury at least one year ago. If you qualify, it may help you restore more regular, efficient sleep after TBI.
Aurora, ColoradoAges 18–60 - NCT05683132Recruiting
Therapy to improve sleep in women with PTSD symptoms
This study is testing treatment approaches for improving insomnia (trouble sleeping) in women Veterans who also have PTSD symptoms. It may help reduce sleep problems and improve day-to-day functioning.
West Los Angeles, CaliforniaAges 18 years+ - NCT05710991Recruiting
Brief therapy for sleep trouble in early pregnancy
This trial compares two short approaches to help with insomnia (sleep difficulties) during early pregnancy: brief cognitive behavioral therapy or sleep hygiene tips. It may help improve how well you sleep without using new or changing medications.
Hamilton, OntarioAges 18–45 - NCT05830877Recruiting
Acupuncture study for long-term trouble sleeping
This trial tests whether acupuncture can improve chronic insomnia, meaning ongoing difficulty falling asleep or staying asleep. You may be asked to complete questionnaires and sleep testing to see how your sleep and stress signals change.
Hangzhou, ZhejiangAges 18–70 - NCT05924425RecruitingPhase 4
Daridorexant for insomnia in early memory decline
This trial tests whether daridorexant can improve sleep in people who have mild cognitive impairment or early Alzheimer’s disease and struggle with insomnia. It may help by improving how long and how well you sleep, with monitoring of sleep patterns and memory-related measures.
MontpellierAges 60–85 - NCT06032377Recruiting
Online therapy for sleep and brain health in older adults
This study tests an online talk therapy program (CBT) to help older adults with both sleep troubles and mild memory or thinking concerns. It's done from home, and aims to improve sleep and brain health.
Ottawa, OntarioAges 60–99 - NCT06062953RecruitingPhase 2/Phase 3
Melatonin or low-dose quetiapine for insomnia in psychiatric disorders
This study tests if melatonin, a low dose of quetiapine, or a placebo can help people with a psychiatric condition who also have trouble sleeping. You may qualify if you have insomnia at least 3 times a week and your sleep problem has lasted 3 months or longer.
Copenhagen NVAges 16–64 - NCT06093126RecruitingPhase 4
Lemborexant for insomnia in dementia: a personalized trial
This trial tests if the sleep medication lemborexant can help people with early-stage dementia who also have insomnia. It uses an N-of-1 design, meaning it will look at how you personally respond to the drug compared to a placebo.
Halifax, Nova ScotiaAges Any age - NCT06109363Recruiting
Sleep improvement program for Chinese adults with insomnia
This study tests a step-by-step counseling program for insomnia (CBT-I) that starts with simple steps and adds more support if needed. It’s for Chinese adults who have trouble sleeping and may help you improve your sleep without medication.
Shatin, New TerritoriesAges 18–70 - NCT06145516Recruiting
Sleep program to ease pain after joint replacement
This study tests whether a sleep program can help with pain after knee or hip replacement. If you have insomnia and arthritis pain, you may be able to join before your surgery.
Uppsala, UpplandAges 18–100 - NCT06149273Recruiting
Treating insomnia in primary care
This study tests a treatment for people who have had trouble sleeping for at least 3 months. It aims to help you sleep better through care you can get from your regular doctor.
TurkuAges 18 years+ - NCT06156306Recruiting
Comparing two sleep and anxiety therapies for young people
This study compares two types of talk therapy to help young people who struggle with both insomnia and anxiety. Both treatments involve learning skills to improve sleep and manage anxious thoughts; one version also includes strategies for accepting difficult emotions.
Shatin, New TerritoriesAges 15–24 - NCT06156293Recruiting
Preventing insomnia step-by-step in Chinese adults
This trial aims to prevent sleep problems from becoming serious by using a step-by-step approach that starts with low-cost, easy treatments and adds more help if needed. It is for Chinese adults who currently have only mild or no insomnia.
Hong KongAges 18–70 - NCT06226259Recruiting
GABA supplement for children with insomnia
This study tests whether a natural supplement called GABA can improve sleep in children ages 6 to 12 who have insomnia. It aims to find a safe, non-medication option for better sleep.
Shanghai, Shanghai MunicipalityAges 6–12 - NCT06251258Recruiting
Reading emotions in faces: insomnia and feelings study
This study looks at how people with and without insomnia recognize emotions on faces. It aims to understand if sleep problems affect emotional understanding.
AngersAges 18–65
Hear when a new Insomnia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for insomnia?
- Yes. Clin2 currently lists 251 recruiting insomnia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a insomnia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a insomnia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.