Clinical trials · Pennsylvania
Kidney Diseases clinical trials in Pennsylvania
We’re tracking 46 recruiting kidney diseases studies with a site in Pennsylvania — including Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT07107945RecruitingPhase 3
Study of empagliflozin for children with chronic kidney disease
This trial tests if empagliflozin, a daily pill, is safe and helps children ages 2–17 with chronic kidney disease (CKD). Your child may be eligible if they have reduced kidney function and elevated protein in their urine, and are already on stable kidney treatments.
Philadelphia, PennsylvaniaAges 2–17 - NCT03991169RecruitingPhase 4
Oral iron for children with chronic kidney disease
This trial studies whether taking iron by mouth can improve iron levels and anemia (low red blood cell counts) in children with chronic kidney disease. It may help reduce fatigue and support normal blood-making, by comparing different approaches for children who meet specific iron test results.
Philadelphia, PennsylvaniaAges 1–21 - NCT07446296Recruiting
Kidney transplant exercise program for older adults
This trial tests whether a special exercise program can help people on the kidney transplant waiting list get stronger and improve their health. You would use an app to follow exercise routines at home and check in with the research team.
Philadelphia, PennsylvaniaAges 60 years+ - NCT07355296RecruitingPhase 2
Testing BI 764198 in adults and teens with kidney disease
This study tests an investigational drug (BI 764198) in adults and teens with different types of kidney disease. The goal is to see if the drug can help slow kidney damage. You may be able to join if your kidney function is at a certain level, you are on stable blood pressure medications, and you haven't had recent strong immune treatments.
Bethlehem, PennsylvaniaAges 12 years+ - NCT07271186RecruitingPhase 2
Study of a New Drug for Diabetic Kidney Disease
This study tests an investigational drug that blocks a protein called ANGPTL3, which may help protect the kidneys in people with type 2 diabetes and diabetic kidney disease. It aims to see if the drug can reduce kidney damage and improve overall health.
Bethlehem, PennsylvaniaAges 18–80 - NCT05312879RecruitingPhase 2/Phase 3
Test drug VX-147 for APOL1-related protein in urine kidney disease
This trial studies whether VX-147 can improve kidney disease caused by an APOL1 gene change, which often leads to protein leaking into the urine. It includes both adults and children and focuses on safety and effectiveness over time.
Philadelphia, PennsylvaniaAges 10–65 - NCT06830629RecruitingPhase 2
MZE829 for APOL1 kidney disease
This trial tests an experimental drug called MZE829 for people with kidney disease linked to the APOL1 gene. It aims to see if the drug can help protect kidney function.
Philadelphia, PennsylvaniaAges 18–68 - NCT06356168Recruiting
Virtual reality for kidney disease patients on dialysis
This trial tests whether using virtual reality (a special headset that shows you a different world) can help people with end-stage kidney disease feel better during their dialysis sessions. It may help reduce stress or discomfort.
Philadelphia, PennsylvaniaAges Any age - NCT05457283RecruitingPhase 3
Finerenone safety study for children with kidney disease
This trial studies how safely finerenone works over 18 months in children and young adults with chronic kidney disease who also take an ACE inhibitor or ARB. It aims to better understand long-term side effects when used together with standard kidney blood-pressure medicines.
Philadelphia, PennsylvaniaAges 1–18 - NCT06824987RecruitingPhase 2
Study of AZD2373 for APOL1-related kidney disease
This trial tests an experimental drug (AZD2373) for people with kidney disease caused by APOL1 gene changes. It aims to find the safest and most effective dose to slow kidney damage.
Butler, PennsylvaniaAges 18–65 - NCT04741646RecruitingPhase 2
Ferric citrate for kids with chronic kidney disease
This Phase 2 study tests ferric citrate, a medicine that helps control phosphate and iron balance, in children with chronic kidney disease. It may help slow problems related to kidney disease by improving lab measures like phosphate levels.
Philadelphia, PennsylvaniaAges 6–18 - NCT06902558RecruitingPhase 2
Study of ABBV-CLS-628 for adults with polycystic kidney disease
This trial tests a new drug, ABBV-CLS-628, for people with autosomal dominant polycystic kidney disease (ADPKD). The goal is to see if it slows kidney function decline and is safe to use.
Bethlehem, PennsylvaniaAges 18–55 - NCT07201025Recruiting
MRI study of kidney disease in ARPKD
This study uses MRI scans to track kidney disease progression in children and adults with ARPKD. It aims to better understand how the disease changes over time, which could help improve future care.
Philadelphia, PennsylvaniaAges 6 years+ - NCT01401998Recruiting
Study collecting information from people with ARPKD
This study looks at medical records, imaging, and genetic testing for people with autosomal recessive polycystic kidney disease (ARPKD). It may help researchers better understand the condition and how it affects the liver and kidneys.
Philadelphia, PennsylvaniaAges Up to 18 years - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Bridgeville, PennsylvaniaAges 18 years+ - NCT03633708RecruitingPhase 3
Etelcalcetide for children with dialysis-related overactive parathyroid hormone
This trial studies etelcalcetide in children who have chronic kidney disease and too much parathyroid hormone while on hemodialysis. It aims to safely lower the hormone levels and help manage related bone/mineral problems.
Philadelphia, PennsylvaniaAges birth–18 years - NCT07222917RecruitingPhase 2
Dapagliflozin with baxdrostat for kidney disease and high blood pressure
This trial tests if adding dapagliflozin to baxdrostat (a new blood pressure drug) reduces protein in urine better than baxdrostat alone in people with chronic kidney disease and high blood pressure. It aims to find a more effective way to protect kidney health.
Media, PennsylvaniaAges 18 years+ - NCT07518719Recruiting
Nutrition and Wellness Program for Kidney Disease
This study tests whether a nutrition and wellness program helps people with early-stage kidney disease manage their condition better. The program combines nutrition guidance, support for lifestyle changes, and care coordination to help protect kidney health.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT00327860Recruiting
Kidney disease in children study that follows patients over time
This is a long-term study that watches children and young adults with chronic kidney disease to understand how the illness changes and to improve care. You may be asked to complete regular visits and questionnaires, and your kidney function will be tracked over time.
Philadelphia, PennsylvaniaAges 6 months–22 years - NCT06013865RecruitingPhase 4
Empagliflozin for kidney transplant recipients
This trial tests if empagliflozin, a diabetes medicine that also protects the kidneys, can help people who have received a kidney transplant. It may be an option if you have reduced kidney function or diabetes after transplant.
Pittsburgh, PennsylvaniaAges 19 years+ - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Sayre, PennsylvaniaAges 18–90 - NCT05497518Recruiting
KidneyCARE study for adults with chronic kidney disease
This study is for adults with chronic kidney disease (CKD), including people on dialysis or with a kidney transplant. It aims to better support kidney care by allowing more community access to research.
Danville, PennsylvaniaAges 18–120 - NCT05106387Recruiting
Study follow-up for people who had a kidney transplant
This study follows adults who previously received vonsetamig in an earlier study and then got a kidney transplant while enrolled. It mainly looks at what happens after the transplant and helps doctors understand outcomes over time.
Philadelphia, PennsylvaniaAges 18–70 - NCT04782258RecruitingPhase 3
Testing the safety of tolvaptan in children with ARPKD
This trial is for children from 28 days old up to 18 years who have a rare kidney disease called ARPKD. It will test if the drug tolvaptan is safe for them. The study helps find new treatment options for kids with this condition.
Pittsburgh, PennsylvaniaAges 4 weeks–18 years
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting kidney diseases studies listed above.
- Children's Hospital of Philadelphia · 8 studies
- Research Site · 4 studies
- Northeast Clinical Research Center · 3 studies
- University of Pennsylvania · 2 studies
- UPMC Children's Hospital of Pittsburgh · 2 studies
- Geisinger Medical Center
- Guthrie Clinic
- Penn Transplant Institute
What taking part in a kidney diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Kidney Diseases trials in other states
Common questions
- Are there kidney diseases clinical trials in Pennsylvania?
- Yes. We're currently tracking 46 recruiting kidney diseases studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a kidney diseases study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a kidney diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New kidney diseases studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.