Clinical trials
Kidney Failure, Chronic clinical trials
Below are recruiting kidney failure, chronic clinical trials, each written for real people, not researchers. We’re tracking 220 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06920927Recruiting
Testing an online decision aid for heart and kidney disease
This study is testing an online tool called 'My Heart and CKD' that helps people with both chronic kidney disease and heart disease make decisions about their care. The goal is to see if it is easy to use and helpful for patients and their doctors.
Calgary, AlbertaAges 18 years+ - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Stanford, CaliforniaAges 18–80 - NCT06593392RecruitingPhase 2
Safety of difelikefalin for itching in teens on dialysis
This trial tests a drug called difelikefalin to see if it safely reduces moderate-to-severe itching in teenagers who are on hemodialysis. Itching is common in kidney disease, and this study aims to find a new treatment option.
ChengduAges 12–18 - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT06278207Recruiting
Finerenone in real-world diabetes and kidney disease
This study looks at how the medication finerenone works in everyday medical practice for people with type 2 diabetes and certain stages of chronic kidney disease. It aims to see how safe and effective the treatment is outside of a clinical trial setting.
Multiple Locations, New JerseyAges 18 years+ - NCT06194591Recruiting
Ultrasound treatment for high blood pressure with kidney disease
This trial tests a new ultrasound treatment on the kidney arteries to see if it can safely lower blood pressure in people with high blood pressure and chronic kidney disease. It may help avoid more invasive procedures.
Lausanne, Canton of VaudAges 18–82 - NCT06110130RecruitingPhase 4
Empagliflozin for kidney health in African American veterans
This study is testing whether the drug empagliflozin (Jardiance) can help protect the kidneys of African American veterans who already have some kidney damage but do not have diabetes. The goal is to see if the drug can reduce damage at the cellular level.
Washington D.C., District of ColumbiaAges 19–90 - NCT05997875Recruiting
Learning about dialysis access options
This study tests a new way to teach people about hemodialysis and the access (the spot in your arm or leg where the dialysis machine connects). It is for people with advanced kidney disease who are considering hemodialysis and want to learn about their options for vascular access.
Baltimore, MarylandAges 18 years+ - NCT05726526Recruiting
Phone app monitoring to help people with advanced kidney disease
This study tests a phone app (with check-ins on things like blood pressure and weight) to help prevent complications in people with advanced chronic kidney disease. You may be a good match if you’re high risk and can actively measure and share your health data with a kidney care team.
Winnipeg, ManitobaAges 18 years+ - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
Washington D.C., District of ColumbiaAges 55 years+ - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT03955172Recruiting
Test of everolimus to reduce transplant rejection
This trial studies whether everolimus can improve outcomes for people whose kidney transplant biopsy shows signs of a specific type of immune attack. It focuses on patients without certain antibodies and with particular biopsy findings, aiming to prevent rejection-related injury while balancing medication side effects.
LyonAges 18 years+ - NCT05327062Recruiting
Noninvasive mapping to guide a heart resynchronization device
This trial tests a noninvasive way to map your heart’s wiring and veins to help guide placement of a heart resynchronization therapy (CRT) device. If you have certain abnormal heart rhythm and weak heart pumping, it may help doctors place the therapy more accurately and safely.
Chicago, IllinoisAges 18 years+ - NCT07535320Recruiting
What Dialysis Treatment Do Patients Prefer?
This research study asks patients with advanced kidney disease about their preferences for different dialysis treatment options before starting treatment. Your feedback helps doctors understand what matters most to patients when choosing how to manage their kidney disease.
CaenAges 18 years+ - NCT07374042RecruitingPhase 3
A supplement to protect muscle in advanced kidney disease
This trial tests whether a special diet supplement (Ketoanalogue) can help protect your muscles while you follow a moderate protein diet. It is for people with chronic kidney disease stage 4 or 5 who are not on dialysis or have not had a kidney transplant.
Clermont-FerrandAges 18–100 - NCT07347275Recruiting
Liver dialysis for severe acute-on-chronic liver failure
This trial tests a new liver dialysis device called DIALIVE 2.0 for people with acute-on-chronic liver failure (a sudden, severe worsening of chronic liver disease). If you qualify, the device will help filter your blood, similar to kidney dialysis, to support your liver while it tries to recover.
London, Greater LondonAges 18–70 - NCT06890039RecruitingPhase 2
Study of a new treatment for severe alcoholic hepatitis
This trial tests an experimental drug for people with severe alcoholic hepatitis that did not improve with steroids. Participants should have a moderate level of organ failure, but not require a breathing tube or kidney dialysis.
London, Greater LondonAges 18–75 - NCT06788054Enrolling by invitation
Exercise during dialysis for fitness and survival
This study tests whether adding exercise during your dialysis sessions can improve your physical fitness, body composition, and survival. If you are on hemodialysis and meet the health criteria, you would either exercise while on the machine or receive standard care.
León, GuanajuatoAges 18–50 - NCT05817539Recruiting
Early circulation-focused care during kidney dialysis in ICU
This trial looks at whether starting dialysis-related care early, aimed at improving blood flow to tissues, can help people in the ICU who have sudden kidney failure. It may help reduce problems related to poor tissue circulation, but it is very specific about ICU illness and current treatments.
AjaccioAges 18 years+ - NCT07403669Recruiting
Heart, kidney, and metabolic health assessment study
This trial offers a health assessment and empowerment program for adults who have heart, kidney, or metabolic conditions like diabetes or heart disease. It aims to help you better manage your health.
Chandler, ArizonaAges 18 years+ - NCT06751602Enrolling by invitationPhase 2
Belumosudil to prevent kidney scarring after transplant
This trial tests whether a drug called belumosudil can reduce scarring in the kidney after transplant. Scarring can lead to kidney damage over time, and this study aims to stop that from happening.
Houston, TexasAges 18–75 - NCT03459534RecruitingPhase 3
Radotinib for CML patients after prior TKI failure
This trial tests radotinib (a targeted pill) in people with chronic-phase Philadelphia chromosome–positive CML whose previous TKIs stopped working or could not be tolerated. It aims to improve control of the leukemia while checking safety.
BarnaulAges 18 years+ - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07134595Recruiting
Comparing two peritoneal dialysis schedules in children with kidney failure
This trial tests a modified version of daily peritoneal dialysis (M-CAPD) versus the standard version (C-CAPD) for children in low-resource settings who have end-stage kidney disease. It aims to see if the modified schedule works better for clearing waste and fluid.
Manila, ErmitaAges 2–18
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Common questions
- Are there clinical trials for kidney failure, chronic?
- Yes. Clin2 currently lists 220 recruiting kidney failure, chronic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a kidney failure, chronic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a kidney failure, chronic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.