Clinical trials
Left Ventricular Systolic Dysfunction clinical trials
Below are recruiting left ventricular systolic dysfunction clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05714085RecruitingPhase 2/Phase 3
Vericiguat study for children with heart failure
This trial tests whether vericiguat helps children with chronic heart failure caused by weaker left heart pumping. It also checks safety and how the medicine behaves in the body (dose and processing).
Los Angeles, CaliforniaAges 4 weeks–17 years - NCT05189860Recruiting
C-MIC system follow-up visits study
This study checks on people who previously received a C-MIC System, usually by asking them to come in for follow-up visits. It helps the team learn how the system is doing over time and supports better care planning.
Banja Luka, Banja LukaAges 18–75 - NCT05388032Recruiting
Test whether lowering salt improves blood vessel health
This trial studies whether a lower-salt plan can improve how your blood vessels work. It’s meant for adults with higher blood pressure who may be at risk for heart and blood vessel problems.
New Orleans, LouisianaAges 40 years+ - NCT05411614Recruiting
Testing two heart procedures for atrial fibrillation in heart failure
This study compares two different ablation procedures (treatments that target heart rhythm triggers) for people with atrial fibrillation and reduced heart pumping. It aims to see which approach works best and is safest for improving your heart rhythm when you also have heart failure.
ChertseyAges 18 years+ - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT06197503Recruiting
Comparing two types of heart pacing after TAVI
This trial compares two ways to pace the heart after a TAVI procedure for people who need a pacemaker. It aims to find which pacing method works better for preserving heart function.
BarcelonaAges 18 years+ - NCT06243653Recruiting
Heart microvessel function test for heart failure recovery
This trial looks at how tiny blood vessels in the heart affect improvement in heart pumping strength for people with heart failure. It tests whether a special procedure during heart catheterization can predict recovery.
SeoulAges 19 years+ - NCT06270498RecruitingPhase 4
Oral iron for heart failure: exercise and quality of life study
This study tests whether an oral iron supplement (a pill called sucrosomial iron) can help people with heart failure who have low iron feel better, have more energy, and walk farther. Participants will take the iron pill or a placebo (a pill without the active ingredient) for a period and will do exercise tests and answer questionnaires to see how they improve.
Pisa, TuscanyAges 18 years+ - NCT06324682Recruiting
Comparing heart pacemaker types for better treatment
This trial looks at different ways to pace the heart (like left, right, or both sides) to see which works best for people who need a pacemaker. If you have a heart condition requiring a pacemaker, this study may help find the safest and most effective option for you.
Ferrara, FEAges 18 years+ - NCT06770062Recruiting
How the heart changes after mitral valve repair surgery
This study at Mayo Clinic uses MRI and other tests to see how the heart's main pumping chamber changes shape after robot-assisted mitral valve repair surgery for severe mitral regurgitation. It may help doctors better understand how patients recover.
Rochester, MinnesotaAges 18 years+ - NCT06811519Recruiting
AI predicts heart function from ultrasound and body scans
This study uses artificial intelligence to predict how well your heart is pumping by looking at your heart ultrasound results and body composition (like body fat and muscle). The goal is to see if adding body composition data makes the AI predictions more accurate.
Yongin, Gyeonggi-doAges 20 years+ - NCT06920030Recruiting
Testing a new heart device for heart failure
This trial tests a new device that delivers a gentle electrical current to the heart to improve its pumping strength. It is for people with a certain type of heart failure caused by weak heart muscle, not a blocked artery.
Banja Luka, Republic of SrbskaAges 18–75 - NCT07188805RecruitingPhase 3
Finerenone for children with heart failure
This study tests a new medicine called finerenone (a pill) to see if it helps children with heart failure who have a weak pumping heart. It compares finerenone to a placebo (a pill with no medicine) while both groups continue their usual heart treatments.
Aurora, ColoradoAges 6 months–17 years - NCT07192952RecruitingPhase 3
Long-term safety of finerenone in children and young adults with heart failure
This study tests the long-term safety of the drug finerenone when taken alongside standard heart failure treatments in children and young adults with weakened heart pumping function (left ventricular systolic dysfunction). It includes both children already in a related study and new infants under 6 months old.
Aurora, ColoradoAges Up to 18 years - NCT07355023Recruiting
AI ECG to guide heart medication for normal pump function
This study uses an AI-enhanced ECG to guide doctors in prescribing heart medications and aims to prevent future heart-pumping problems. It may help you if your heart function is currently normal and you have recent heart tests.
Taipei, TaipeiAges 18 years+ - NCT06707662Recruiting
Pacing methods to protect heart function
This trial tests two pacing approaches to see which one better prevents weakening of the heart's main pumping chamber. It's for people who need a pacemaker for a slow heart rhythm and are expected to rely on it heavily.
BarcelonaAges 18 years+ - NCT04950218Recruiting
Study risks of heart problems in people with psoriasis
This study asks adults with psoriasis about factors that may be linked to heart problems. It aims to better understand who is at higher risk, which could help guide future prevention and care.
Hellerup, CopenhagneAges 18 years+ - NCT04680442RecruitingPhase 2
Keeping HER2 therapy when your heart function is weaker
This trial studies whether it’s safe to continue HER2-targeted breast cancer treatment (like trastuzumab, pertuzumab, or T-DM1) even when heart function (left ventricle) is reduced. It may help people avoid stopping a helpful cancer medicine because of heart concerns.
Porto Alegre, Rio Grande do SulAges Any age - NCT05764057RecruitingPhase 3
Dapagliflozin to help the heart heal after a heart attack
This trial tests whether dapagliflozin (a diabetes medicine also used for heart protection) can reduce harmful heart “remodeling” after an acute heart attack. It may help your heart function and structure recover over the following 6 months.
ParisAges 18 years+ - NCT04265040Recruiting
Heart muscle disease registry for non-ischemic conditions
This trial is a registry, meaning it collects health information to help doctors study heart muscle diseases and plan future cardiovascular studies. You may be able to join if you have a non-ischemic cardiomyopathy such as dilated cardiomyopathy, certain forms of thick heart muscle, non-compaction, or arrhythmogenic right-sided disease.
Heidelberg, Baden-WurttembergAges 18–80 - NCT06105580Recruiting
Pacing methods for heart failure with wide QRS
This trial compares two ways to pace the heart in people with heart failure and a wide QRS (a sign the heart's electrical signals are slowed). The goal is to see which method better reduces the risks of death, heart failure hospitalization, or needing a heart transplant.
BarcelonaAges 18 years+ - NCT07094919Recruiting
Corheart 6 heart pump long-term study
This study follows people who have already received the Corheart 6 heart pump to see how well it works over time. You may qualify if you have severe heart failure that doesn't improve with standard treatments and you got the pump after October 1, 2021.
Shenzhen, GuangdongAges 18 years+ - NCT07636759Recruiting
AI Heart Rhythm Test for Heart Pump Weakness
This study tests whether an artificial intelligence system can detect a weakened heart pump using an ECG (heart rhythm test). If successful, it could help doctors diagnose heart problems faster and more easily.
Suwon, Gyeonggi-doAges 19 years+
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Left Ventricular Systolic Dysfunction trials by city
Studies with a site in or near these metro areas.
Left Ventricular Systolic Dysfunction trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for left ventricular systolic dysfunction?
- Yes. Clin2 currently lists 23 recruiting left ventricular systolic dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a left ventricular systolic dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a left ventricular systolic dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.