Clinical trials
Liver Cancer (Locally Advanced or Metastatic) clinical trials
Below are recruiting liver cancer (locally advanced or metastatic) clinical trials, each written for real people, not researchers. We’re tracking 5,821 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01280825Recruiting
Testing how to use genetic medicine results in routine care
This study looks at how to put genetic testing results (pharmacogenomics) into regular doctor care. It aims to see whether using the results helps doctors choose safer, better-matched medications.
Chicago, IllinoisAges 18 years+ - NCT02064673RecruitingPhase 3
Adjuvant curcumin after prostate surgery to prevent cancer return
This Phase 3 trial studies whether taking curcumin (a supplement made from turmeric) after radical prostatectomy can help keep prostate cancer from coming back. Participants are men with low-risk, surgery-only disease and undetectable PSA, and the study checks recurrence-free survival over time.
Dallas, TexasAges 30–80 - NCT01438658Recruiting
Test blood markers to help diagnose metastatic uveal melanoma
This study checks whether blood “biomarkers” (measurable signs in serum) can help diagnose metastatic uveal melanoma. If you have uveal melanoma, the study may look at how useful these blood tests are for spotting spread to other parts of the body.
JerusalemAges Any age - NCT01913106RecruitingPhase 1/Phase 2
Testing valacyclovir with an added cancer gene in prostate radiation
This Phase 1/2 study tests whether adding a cancer-targeting gene therapy (HSV-tk) and the antiviral medicine valacyclovir to brachytherapy can better treat recurrent prostate cancer in the prostate area. It may help by making cancer cells more vulnerable to the treatment.
Houston, TexasAges Any age - NCT01535430Recruiting
Mapping brain function in people with certain brain tumors
This study uses brain “mapping” tests (with MRI and possibly other methods) to identify important brain functions near a tumor. It may help your care team plan a safer surgery by understanding which brain areas do critical tasks.
Omaha, NebraskaAges 19 years+ - NCT01887340RecruitingPhase 2
PET-guided treatment for seminoma based on scan response
This Phase 2 study tests a treatment plan guided by a PET scan over time in people with seminoma after testicle removal. It aims to tailor therapy based on how cancer shows up on the scan, potentially helping avoid unnecessary treatment intensity.
Villejuif, Val de MarneAges 18 years+ - NCT02250352Recruiting
Biopsy study to collect breast tumor tissue samples
This study takes small tissue samples (core biopsies) from people with known or suspected breast cancer and stores them for research. It may help scientists better understand breast tumors, especially when the cancer has spread.
Los Angeles, CaliforniaAges 18 years+ - NCT02582697RecruitingPhase 3
Faster vs standard chemotherapy for spreading germ cell tumors
This Phase 3 trial compares a faster chemotherapy approach versus the standard schedule for people with intermediate- or poor-risk metastatic germ cell tumors. The goal is to see which schedule works better and is safer enough to use as initial treatment.
New York, New YorkAges 11–50 - NCT02381990Recruiting
MRI- and ultrasound-guided freezing treatment for low-risk prostate cancer
This trial tests using MRI and ultrasound together to guide freezing (cryoablation) treatment for prostate cancer. It may help target the tumor more precisely while avoiding areas that could cause side effects.
Miami Lakes, FloridaAges 55 years+ - NCT02838602Recruiting
Carbon beam radiation vs standard radiation for resistant tumors
This study compares carbon beam radiation with standard radiation for tumors that are less likely to respond to usual radiation. It aims to see whether carbon beams can improve control of the cancer while keeping side effects manageable.
AmiensAges 18 years+ - NCT02910895Recruiting
Test of lab-grown sarcoma samples to guide treatment research
This study uses tumor samples from soft tissue sarcoma to create lab models that researchers can test. It may help scientists better understand sarcoma and find more personalized treatment ideas for people like you.
AmsterdamAges 18 years+ - NCT02246634Recruiting
MRI screening to find liver metastases in bowel cancer
This study checks whether a special MRI scan (DW-MRI) can spot liver metastases early in people with high-risk colorectal cancer. Finding metastases sooner may help doctors choose the right treatment path.
Macclesfield, CheshireAges 16 years+ - NCT02389673Recruiting
Radiation during breast surgery for low-grade DCIS
This trial studies giving radiation during surgery for women with a certain early breast condition called ductal carcinoma in situ (DCIS). It may help lower the chance that the DCIS comes back, especially when combined with breast-conserving surgery.
Guangzhou, GuangdongAges 18–70 - NCT02704520Recruiting
MRI scoring test for rectal cancer response to treatment
This study looks at how an MRI “score” (mrTRG) matches how well locally advanced rectal cancer shrinks after pre-surgery chemotherapy and radiation. The goal is to use MRI results to better predict treatment response and guide care.
Aberdeen, AberdeenshireAges 16 years+ - NCT02870244RecruitingPhase 1
Engineered T-cell therapy for advanced melanoma patients
This Phase 1 study tests a lab-made immune cell treatment for advanced melanoma. It aims to see if engineered T-cells can recognize the patient’s tumor and help control the cancer, especially in specific melanoma tissue markers.
Maywood, IllinoisAges 18–89 - NCT03042221Recruiting
Early re-biopsy to find why tumors survive targeted drugs
This study takes a small tumor sample early after starting targeted treatment (or uses blood if a biopsy isn’t possible) to look for clues—called biomarkers—about why some tumor cells survive. The results may help improve how future patients’ treatments are chosen for certain lung cancer gene mutations.
Aurora, ColoradoAges 18–85 - NCT03209791Recruiting
Study alcohol-related effects on muscle recycling in the liver
This study looks at how alcoholic liver disease may change a natural body clean-up process in muscle. It compares people with alcoholic liver disease to people without it to better understand the biology and identify possible targets for treatment.
Cleveland, OhioAges 18–65 - NCT03125642RecruitingPhase 2
Auto stem cell transplant for lymphoma after chemo
This Phase 2 study tests an auto (self) stem cell transplant for people with certain types of non-Hodgkin lymphoma or Hodgkin lymphoma who respond to chemotherapy (they are “chemo-sensitive”). It may help some patients get a deeper or longer remission by resetting the bone marrow after high-dose treatment.
Minneapolis, MinnesotaAges Up to 75 years - NCT06246149RecruitingPhase 3
Tebentafusp after treatment for high-risk eye melanoma
This trial tests a new drug called tebentafusp given after standard treatment (surgery or radiation) for high-risk uveal melanoma that hasn't spread. The goal is to see if it helps prevent the cancer from coming back.
Lake Success, New YorkAges 18 years+ - NCT07059221RecruitingPhase 1/Phase 2
New drug combo for advanced head and neck cancer
This trial tests a new combination of drugs (SHR-A2102 and Adebrelimab) with or without other anti-cancer therapies for head and neck cancer that has come back or spread. It aims to see if these treatments can shrink tumors or slow the disease.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07450859RecruitingPhase 2
Nuzefatide Pevedotin for Metastatic Pancreatic Cancer
This trial tests a new drug called nuzefatide pevedotin (BT5528) for people with metastatic pancreatic cancer. It targets a specific marker on cancer cells (EphA2) and may help when other treatments have stopped working.
St Louis, MissouriAges 18 years+ - NCT02526797Enrolling by invitation
MRI scan study for men on active surveillance
This trial tests how a special MRI scan (with multiple measurements) may help men with low-risk prostate cancer who are monitoring it closely instead of treating right away. It may help doctors better understand the cancer’s status during active surveillance.
HerlevAges 18–75 - NCT00900497Enrolling by invitationPhase 1/Phase 2
Donor white blood cells to treat solid tumors
This Phase 1/2 study tests whether donated white blood cells (granulocytes) from healthy donors can help treat solid cancers that cannot be cured or have stopped responding to standard treatments. The goal is to see safety first, and then whether the treatment can shrink or control tumors.
Boynton Beach, FloridaAges 18 years+ - NCT07398339RecruitingPhase 2
Photodynamic therapy for bile duct cancer
This trial tests a light-activated drug called cosiporfin sodium for people with advanced bile duct cancer that cannot be surgically removed. The treatment targets tumors in the bile ducts and may help shrink them.
Shanghai, Pudong New AreaAges 18 years+
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Common questions
- Are there clinical trials for liver cancer (locally advanced or metastatic)?
- Yes. Clin2 currently lists 5,821 recruiting liver cancer (locally advanced or metastatic) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver cancer (locally advanced or metastatic) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver cancer (locally advanced or metastatic) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Locally Advanced or Metastatic Breast Cancer
- Locally Advanced or Metastatic Non-small Cell Lung Cancer
- Colorectal Cancer (Locally Advanced or Metastatic)
- Lung Cancer (Locally Advanced or Metastatic)
- Locally Advanced Rectal Cancer
- Locally Advanced Cervical Cancer
- Locally Advanced Breast Cancer
- Locally Advanced or Metastatic Solid Tumors
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.