Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06656767Enrolling by invitation
Studying liver cell changes in chronic liver disease
This trial uses already collected liver tissue samples from adults to study how cells change over time in chronic liver disease. It could help researchers understand the disease better and find new ways to treat it.
CambridgeAges 18 years+ - NCT05744713Enrolling by invitation
Study of adults with long-term liver disease using health records
This observational study looks at adults with chronic liver disease (including cirrhosis) to better understand how people are managed and how they feel over time. Because it does not change your treatment, it may help researchers improve care and patient support.
Los Angeles, CaliforniaAges 18 years+ - NCT06596616Enrolling by invitation
Comparing two MRI contrast agents for liver imaging
This trial tests whether a newer contrast agent, gadopiclenol, works as well as the standard one for liver scans. It might be an option if you need an MRI to check for liver disease, tumors, or treatment response.
New York, New YorkAges 18–89 - NCT06531278RecruitingPhase 2
Adebelimab plus chemo for first-line pancreatic cancer with liver spread
This trial tests a combination of immunotherapy (adebelimab) and chemotherapy drugs (irinotecan liposome, oxaliplatin, fluorouracil, and calcium folinate) as a first treatment for pancreatic cancer that has spread to the liver. The goal is to see if this combination is safe and effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06994871Enrolling by invitation
Exercise and liver fat in fatty liver disease
This study tests if different types of exercise can reduce fat in the liver for people with metabolic fatty liver disease. It might help if you are looking for a non-drug way to improve your liver health.
Nanjing, JiangsuAges 18–45 - NCT07205471Recruiting
Partial spleen removal via laparoscopy for cirrhosis-related hypersplenism
This study is testing a keyhole surgery to remove part of an enlarged spleen in people with cirrhosis. It aims to improve low blood counts and reduce the risk of further bleeding from stomach or esophagus veins.
Yangzhou, JiangsuAges 18 years+ - NCT07199491Enrolling by invitation
Healthy lifestyle program for Hispanics with fatty liver disease
This trial tests a culturally tailored lifestyle program for Hispanic adults with fatty liver disease (MASLD). It aims to help improve liver health through diet and activity changes with support from a family member.
Houston, TexasAges 18 years+ - NCT06048445Recruiting
Preventing bile duct issues after children's liver transplant
This trial tests placing a temporary drainage stent during liver transplant surgery in children to see if it helps prevent bile duct complications. It might improve recovery for young transplant recipients.
Hangzhou, ZhejiangAges 1–6 - NCT07247877Enrolling by invitation
Study of small liver grafts for portal hypertension treatment
This trial explores using smaller liver grafts in a partial transplant to treat portal hypertension, which may help patients avoid full transplant risks. It compares this approach to standard liver transplant.
Ages 14 years+ - NCT07284836RecruitingPhase 2
Chemo directly to liver for breast cancer
This trial tests a new way to give chemotherapy directly to the liver for breast cancer that has spread only there. It's for people who have already tried two or more standard treatments.
Hangzhou, ZhejiangAges 18–70 - NCT07042308Recruiting
Study of advanced chronic liver disease over time
This study follows people with advanced chronic liver disease to understand how their condition changes over time. If you have cirrhosis or high liver stiffness, you may be able to join to help researchers track the disease and learn more about it.
Hong KongAges 18 years+ - NCT06857331Recruiting
Numbing block for pain after liver transplant
This trial tests a special numbing injection (erector spinae plane block) to help control pain after liver transplant surgery. It may be a good option if you have severe liver disease and need a transplant.
KyivAges Any age - NCT07015723Enrolling by invitation
Liver fat study in living donors
This study looks at stored medical data from living liver donors to better understand fat in the liver (steatosis). It may help improve future transplant care.
Rotterdam, South HollandAges 18–60 - NCT06994429Enrolling by invitation
New MRI to check liver function after transplant
This study uses a new MRI technique to check how well your new liver is working after transplant, without any needles or biopsy. If you have had a liver transplant and are scheduled for an MRI, you may be able to join.
Wuhan, HubeiAges 18–80 - NCT07441369Enrolling by invitationPhase 2
Abemaciclib with chemotherapy for advanced colorectal liver metastases
This trial tests combining the targeted drug abemaciclib with standard chemotherapy (FOLFOX or FOLFIRI) for people whose colorectal cancer has spread to the liver and cannot be removed surgically. It may be an option if you've already tried two or three prior treatments without success.
ShanghaiAges 18–75 - NCT05953948Enrolling by invitation
Smartphone case management program for liver transplant patients
This trial studies whether an “intelligent” phone-based case management program can help people after a liver transplant. You may be able to participate if you’re a liver transplant recipient and can use a smartphone, but not if you have liver-related confusion.
Taoyuan, TYAges 20 years+ - NCT06935994RecruitingPhase 2
Aspirin for Fatty Liver Disease (MASLD)
This study tests whether aspirin can help people with MASLD, a type of fatty liver disease linked to conditions like diabetes and obesity. It aims to see if aspirin can improve liver health without causing harm.
Taichung, TaiwanAges 18 years+ - NCT06716541Recruiting
Biodegradable stent for bile duct narrowing after liver transplant
This study is testing a special temporary stent that breaks down over time to help open a narrowed bile duct after a liver transplant. It may help avoid long-term plastic stents or additional surgery.
PragueAges 18 years+ - NCT03717792Recruiting
Check how doctors follow up vascular liver disease
This study focuses on people who have vascular liver disease and aims to evaluate follow-up care and non-invasive ways to assess it. It may help improve how safely and accurately doctors monitor your liver without invasive procedures.
BonnAges 18–100 - NCT06899867Recruiting
Comparing heart monitoring methods during liver transplant
This trial compares two ways to monitor how well your heart is pumping during liver transplant surgery. One method uses a thin tube in your blood vessels, and the other uses an ultrasound probe placed in your food pipe.
France, LyonAges 18 years+ - NCT06876805Recruiting
Ultrasound contrast to check unclear liver spots
This trial uses a special ultrasound with contrast dye to get a clearer picture of liver spots that other scans (CT, MRI, or PET) couldn't fully identify. The goal is to see if this ultrasound can help doctors make a more accurate diagnosis.
BolognaAges 18 years+ - NCT07456332Enrolling by invitation
Digital lifestyle program for weight loss with HIV and fatty liver
This trial tests a digital lifestyle program (diet and activity coaching) to help people with HIV and fatty liver disease lose weight. It aims to see if the program can reduce body fat in the liver and improve overall health.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07288281Recruiting
Preoperative Clear Fluid Fasting in Liver Transplant
This trial looks at how long before surgery patients waiting for a liver transplant can drink clear fluids, like water. The goal is to find a safer or more comfortable fasting time.
Warsaw, WarszawaAges 18 years+ - NCT01697371Recruiting
Proton beam radiation for liver metastases
This trial tests whether proton beam therapy can control cancer that has spread to the liver. It may help shrink liver tumors or slow their growth while aiming to reduce harm to nearby organs.
Loma Linda, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,253 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.