Clinical trials
Lower Limb clinical trials
Below are recruiting lower limb clinical trials, each written for real people, not researchers. We’re tracking 205 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04487314Recruiting
Study of chronic vein disease over time
This study follows people (and certain close family members) to document how chronic vein problems develop and change over time. You would get yearly checkups and ultrasound scans to track the natural course of the condition.
Saint Petersburg, Sankt-PeterburgAges 10 years+ - NCT03995238Recruiting
Gait training for veterans with leg amputations
This study tests a walking rehabilitation plan to improve how you walk after a lower-leg amputation. It may help if your walking steps are uneven and you have diabetes and/or circulation problems in your legs.
Aurora, ColoradoAges 40–89 - NCT03409133Recruiting
Neural feedback training for people with leg amputations
This study tests whether a nerve-based “feedback” system can help people with below-knee or above-knee amputations during standing and walking. It focuses on whether the training and device setup are safe and workable for participants over the study period.
Cleveland, OhioAges 18 years+ - NCT05646316RecruitingPhase 3
Sentinel lymph node mapping to reduce leg swelling after surgery
This study tests whether a special way of finding lymph nodes during hysterectomy can lower the risk of long-term leg swelling or related dysfunction in people with stage I endometrial cancer. It compares standard lymph node assessment with sentinel lymph node mapping and looks at how this affects day-to-day leg functioning.
Washington D.C., District of ColumbiaAges 18 years+ - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT07387653Recruiting
Leg circulation monitoring during pelvic surgery
This trial tests a new way to check blood flow and oxygen levels in your legs during pelvic surgery when you're in the lithotomy (legs-up) position. It aims to catch any circulation problems early, which could help prevent leg injuries.
Houston, TexasAges Any age - NCT07766954Enrolling by invitationPhase 1
Exercise program for older adults living at home
This trial tests a gymnastics and multi-exercise program for people aged 60 and older who live at home. The goal is to see if this program improves strength, balance, and overall health.
Salvador, Estado de BahiaAges 60–105 - NCT07610850Recruiting
Brain-controlled stimulation to improve arm and leg movement after stroke
This trial tests a new brain-controlled device that sends electrical signals to your spinal cord to help restore arm and leg movement after a stroke. If you had a stroke at least 9 months ago and have weakness on one side of your body, this may help you regain function.
Lausanne, Canton of VaudAges 18–70 - NCT07084740Recruiting
Study of blood flow in skin flaps for reconstruction
This study looks at how blood flows through special skin flaps used in reconstructive surgery. It may help doctors better understand and predict how these flaps heal, especially for people who need repair after injuries or pressure sores.
MontpellierAges 18–70 - NCT07353905Recruiting
Ultrasound guidance for leg artery treatment
This trial tests whether using a special ultrasound probe inside the artery (intravascular ultrasound) helps doctors better treat blocked leg arteries. It may lead to more effective procedures for patients with leg pain or wounds due to poor blood flow.
Dallas, TexasAges 18 years+ - NCT03135847Enrolling by invitation
Using feedback to improve prosthetic movement in amputees
This study tests whether movement “feedback” can help adults with arm or leg amputations control a prosthetic better. It may be most helpful if you can comfortably wear a prosthetic socket and can understand and consent to the study.
Ages 18–75 - NCT07749612Recruiting
Robotic arm trainer for stroke and brain injury recovery
This trial tests a robotic device that helps people move their arms and hands during rehabilitation after a stroke, brain injury, or spinal cord injury. The goal is to improve arm function and make daily tasks easier.
DhakaAges 18–60 - NCT07749625Recruiting
Robotic arm training for recovery after stroke or injury
This study tests whether a robotic arm trainer can help improve arm movement and function in people with conditions like stroke, spinal cord injury, or brain injury. It may help you regain strength and control in your arm.
DhakaAges 18–60
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Common questions
- Are there clinical trials for lower limb?
- Yes. Clin2 currently lists 205 recruiting lower limb studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lower limb trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lower limb trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.