Clinical trials
Lumbar Decompression clinical trials
Below are recruiting lumbar decompression clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07060781Recruiting
Managing fluid buildup after lower back surgery
This trial tests ways to prevent or reduce seroma (fluid buildup) after elective lower back decompression surgery. It aims to improve recovery and comfort for patients.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT07139938Recruiting
Spinal decompression without implants for lumbar stenosis
This trial tests whether removing pressure on spinal nerves alone, without any hardware, can help fix spine balance and reduce pain in people with lumbar stenosis. It is for those who have had leg pain or trouble walking for at least 3 months and plan to have surgery without implants.
MoscowAges 18 years+ - NCT07045714Recruiting
Endoscopic back surgery for spinal stenosis
This study looks at a newer, less invasive type of back surgery called endoscopic laminotomy. It may help people with lumbar spinal stenosis (narrowing of the spinal canal) who still have leg or back pain after trying physical therapy and pain medicines for at least 3 months.
San Pedro Garza García, Nuevo LeónAges 18–74 - NCT05444751Enrolling by invitationPhase 3
Different pain medicine plans for back surgery
This Phase 3 study compares two combinations of anesthesia and pain medications during lumbar decompression surgery, to see which helps more. It may help patients by aiming for better pain control and recovery using one planned medication approach.
New York, New YorkAges 18–80 - NCT07281625RecruitingEarly Phase 1
Comparing two types of back surgery for lumbar spinal stenosis
This study compares two surgical approaches for patients with lumbar spinal stenosis (a narrowing of the spine that puts pressure on nerves). One group will get standard decompression (relieving pressure), the other group will get that plus screws and rods to stabilize the spine. The goal is to see which leads to better outcomes.
Lahore, Punjab ProvinceAges 30–60 - NCT07289737Recruiting
Comparing two spine surgeries for a slipped backbone
This study compares two types of spine surgery for a common condition where a lower back bone slips forward. It aims to see which surgery works better to relieve pain and improve function.
Yiwu, ZhejiangAges 50–90 - NCT04992572RecruitingEarly Phase 1
Comparing two types of anesthesia for back decompression surgery
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
Redwood City, CaliforniaAges 40–95 - NCT05058287RecruitingPhase 3
Steroid shot during low-back surgery
This trial tests whether using a steroid medicine (a steroid shot) around the time of low-back decompression surgery improves pain and recovery. It is for adults having a limited-area laminectomy, and it compares steroid use versus not using it.
New York, New YorkAges 18–85 - NCT03072927Recruiting
Study of Medicare patients after mild back decompression
This study uses Medicare records to look at outcomes for people who receive MILD or an interspinous process decompression procedure for lumbar spinal stenosis with nerve symptoms. It may help confirm how well these less-invasive procedures work in real-world patients.
Athens, AlabamaAges 18 years+ - NCT06820736Recruiting
Comparing drain methods after low back surgery
This study compares two different methods of using a tube (drain) to remove fluid after low back surgery. It aims to see which drain technique leads to fewer problems or better recovery for people having one or two levels of back surgery.
Minneapolis, MinnesotaAges 18–70 - NCT05452694Recruiting
Personalized pain relief after back fusion surgery
This trial tests a personalized plan to manage pain after lumbar (lower back) fusion and decompression surgery. It may help reduce difficult pain while guiding safe use of opioids around the time of surgery.
Pittsburgh, PennsylvaniaAges 18–99 - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT04066296RecruitingPhase 2
Testing a numbing medicine to improve back decompression outcomes
This Phase 2 study looks at whether a long-lasting local pain medicine (liposomal bupivacaine) can improve recovery and outcomes after surgery for lumbar stenosis (narrowing in the lower spine). You may be considered if you’re an adult needing decompression surgery and do not have reasons that would make surgery unsafe or different from the study’s plan.
Aurora, ColoradoAges 18 years+ - NCT06407063Recruiting
Long-term results after surgery for lumbar spinal stenosis
This study looks at patients who had back surgery for lumbar spinal stenosis and a condition called spondylolisthesis between 2007 and 2015. They want to see how many people needed another operation years later.
TromsøAges 18 years+ - NCT06057428Recruiting
Activity levels in seniors having spine surgery
This study is tracking how active people are before and after surgery for lumbar spinal stenosis (a common cause of back and leg pain in older adults). It aims to see if activity monitoring can help improve recovery.
KøgeAges 65 years+ - NCT06075862Recruiting
Balance in patients with lumbar spinal stenosis
This study looks at balance problems in older adults with lumbar spinal stenosis, a condition that narrows the spinal canal and can cause pain or trouble walking. It may help doctors understand how surgery affects balance and daily life.
KøgeAges 65 years+ - NCT06523426Recruiting
Outpatient spine surgery for adults over 75
This trial tests a minimally invasive spine surgery (endoscopic decompression) done as an outpatient procedure in people 75 and older. It aims to see if this approach is safe and effective for treating a single-level lumbar spine problem.
BordeauxAges 75 years+ - NCT06942819Enrolling by invitation
MRI study of VersaWrap nerve protector after back surgery
This trial uses MRI scans to see how well a nerve protector called VersaWrap works after one-level lumbar decompression surgery. It may help understand if the device helps nerves heal better.
Austin, TexasAges 18–65 - NCT04552145Recruiting
Physical therapy versus surgery for lumbar spinal stenosis
This study compares physical therapy to surgery to help relieve symptoms from narrowing in the lower spine. It looks at which treatment works best for walking discomfort caused by spinal stenosis.
LillehammerAges 50–80 - NCT05273879Recruiting
Testing whether one-level fusion is needed after lumbar decompression
This trial compares outcomes after decompression surgery for one affected area in the lower back, with and without adding spinal fusion. It may help patients avoid unnecessary extra surgery—or ensure fusion is used when it’s needed.
Moscow, MoscowAges 45–75 - NCT04469387Recruiting
Reduce adjacent back pain after lumbar surgery
This trial looks at whether a limited decompression (a careful nerve-space “freeing” procedure) can help prevent future problems in the spinal level next to your planned surgery. It targets people with spinal canal narrowing next to the surgery level but who do not yet have symptoms there.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for lumbar decompression?
- Yes. Clin2 currently lists 21 recruiting lumbar decompression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar decompression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar decompression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.