Clinical trials
Lumbar Radiculopathy clinical trials
Below are recruiting lumbar radiculopathy clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07726823Recruiting
Two types of manual therapy for leg pain from a bulging disc
This study compares two gentle, hands-on physical therapy techniques to see which better relieves leg pain from a bulging lower back disc. Participants will receive one of the two treatments over several sessions.
Lahore, Punjab ProvinceAges 20–40 - NCT06846970Recruiting
Hot spring therapy plus physical therapy for chronic back pain
This study tests whether adding hot spring therapy (balneotherapy) to a standard physical therapy program can improve pain and function for people with chronic nerve-related back pain. It may help if you have long-term sciatica-like pain and have not had recent hot spring treatments.
Afyonkarahisar, CentralAges 18–75 - NCT06990113Recruiting
Release therapy and motor control for low back and leg pain
This trial tests a combination of myofascial release (a hands-on therapy for tight muscles) and motor-control exercises to see if they can improve pain and movement in people with long-term nerve-related leg pain from the lower back.
Al Jīzah, Select StateAges 35–50 - NCT07050966Recruiting
Two hand therapies for nerve pain in the leg
This study compares two gentle hand techniques (Maitland and Mulligan) to see which one better relieves leg pain from a pinched nerve in the lower back. If you have chronic sciatica-type pain, these treatments may help without surgery.
IslamabadAges 18–65 - NCT07328282Recruiting
Comparing two therapies for leg pain from a disc problem
This study compares two types of gentle movement therapies to see which works better for leg pain caused by a mild disc problem in the lower back. It may help you if you have pain going down one leg and meet a few specific physical exam findings.
Islamabad, Punjab ProvinceAges 30–50 - NCT07573124Recruiting
Physical therapy techniques for lower back nerve pain
This study tests whether combining three physical therapy techniques—spine mobilization, leg movements, and spinal traction—can reduce pain and improve function in people with pinched nerves in the lower back caused by a bulging disc. If it works, it could offer a non-surgical treatment option.
Islamabad, CapitalAges 20–50 - NCT06421558Recruiting
Electrical stimulation for lower back nerve pain
This study tests whether a mild electrical stimulation applied to the lower back can help relieve pain from a pinched nerve. It involves weekly sessions for 6 weeks.
Escondido, CaliforniaAges 18 years+ - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT07721220Recruiting
Nerve gliding moves for strength and endurance in athletes
This study tests whether a gentle nerve-stretching technique (neurodynamics) can improve leg strength and endurance in athletes. If you're 18–30, currently active in sports or intense training, and have no recent leg injury or surgery, you may be able to join.
High Point, North CarolinaAges 18–30 - NCT06651775Recruiting
High-Intensity Laser Therapy for Chronic Leg Pain from Herniated Disc
This study tests whether a type of high-intensity laser therapy (HILT) can help relieve leg pain caused by a herniated disc in the lower back. It is for people who have not had recent back treatments or surgery.
Ankara, CankayaAges 18–65 - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT04540068Recruiting
Predicting whether a sciatica procedure will work
This study looks for ways to predict how well a specific sciatica procedure (TEI) will help. If you have one-sided nerve pain from the low back, the trial may help personalize treatment so you’re less likely to go through ineffective care.
HaarlemAges 18 years+ - NCT06767280Recruiting
Testing calf muscle in chronic nerve pain patients
This study looks at how a muscle in your calf (gastrocnemius) responds to a gentle electrical test in people with long-term nerve pain from the lower back. It aims to learn more about how the condition affects muscle function, which could help improve future treatments.
Sixth of October, Giza GovernorateAges 18–55 - NCT07222787Recruiting
Testing a new spinal implant for lower back fusion
This trial tests a new spinal implant system (CORUS-LX) for fusing two lower back discs that are causing pain. It is meant for people with severe, long-lasting back or leg pain that hasn't improved with non-surgical treatments.
Scottsdale, ArizonaAges 18–80 - NCT06143813Recruiting
Precision treatment for lumbar nerve pain with targeted block
This trial tests if a targeted nerve root injection can improve outcomes for people with persistent leg pain from a compressed nerve in the lower back, with the goal of tailoring surgery more precisely.
Aarhus CAges 18 years+ - NCT05444751Enrolling by invitationPhase 3
Different pain medicine plans for back surgery
This Phase 3 study compares two combinations of anesthesia and pain medications during lumbar decompression surgery, to see which helps more. It may help patients by aiming for better pain control and recovery using one planned medication approach.
New York, New YorkAges 18–80 - NCT06795542Enrolling by invitationPhase 2
Predicting success of epidural shots for leg pain from a slipped disc
This trial looks at what factors help predict whether a steroid injection into the spine (transforaminal epidural injection) will work for leg pain caused by a herniated disc. It aims to help doctors choose the best treatment for patients like you.
Sohag, Sohag GovernorateAges 18–60 - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT07313566Recruiting
Rehab pathway vs usual care after lumbar spine surgery
This trial compares a new rehab program called R3 (which includes pre-surgery preparation and post-surgery recovery support) with standard care for people having lumbar spine surgery. It aims to see if the R3 pathway helps you recover better and return to work faster.
AntwerpAges 18–65 - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+ - NCT07688915Recruiting
High-intensity laser vs. steroid injection for chronic back and leg pain from a herniated disc
This study compares two treatments for long-lasting low back and leg pain caused by a herniated disc: high-intensity laser therapy and a steroid shot near the spine. Researchers want to see which option works better to reduce pain.
AnkaraAges 18–65 - NCT07125027Recruiting
A mind-body program for leg pain from back issues
This trial tests a program called Move-MORE that combines movement and mindfulness to help people with long-lasting leg pain caused by a nerve problem in the lower back. It involves daily activities, weekly virtual group meetings, and tracking your progress with a wearable device.
Portland, OregonAges 18–66 - NCT07627308Recruiting
Ultrasound vs Fluoroscopy for Nerve Injections in Back Pain
This trial compares two imaging methods—ultrasound and fluoroscopy (X-ray)—to guide nerve injections for leg pain caused by compressed nerves in the lower back. The goal is to see which method is safer and more effective at relieving your pain.
Tanta, Gharbia GovernorateAges 18–75 - NCT06264297Recruiting
Nerve radiofrequency treatment for chronic leg pain
This trial tests a new type of treatment (high-voltage pulsed radiofrequency) that uses a special needle to deliver energy to the nerve root in your lower back. The goal is to see if it can reduce chronic leg pain caused by a pinched or irritated nerve.
Terrassa, BarcelonaAges 18 years+
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Lumbar Radiculopathy trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for lumbar radiculopathy?
- Yes. Clin2 currently lists 33 recruiting lumbar radiculopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar radiculopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar radiculopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.