Clinical trials
Lung cancer clinical trials
Cancer that begins in the lungs, often linked to smoking but also affecting non-smokers. We’re tracking 2,039 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03290534RecruitingPhase 2
Implantable radiation sheet for early-stage lung cancer
This Phase 2 study tests whether a permanently implanted, low-dose radiation “sheet” can be used to treat certain early-stage lung cancers. It may help shrink or control tumors while delivering radiation directly at the cancer site.
New York, New YorkAges 18 years+ - NCT05136846RecruitingPhase 1
Papaverine with chemoradiation for stage II–III lung cancer
This early-phase trial tests whether adding papaverine to standard chemoradiation can improve treatment for stage II–III non-small cell lung cancer (and some limited stage IV cases). It aims to see if the combination is safe and tolerable while targeting the cancer with radiation and chemotherapy.
Duarte, CaliforniaAges 18 years+ - NCT05965557Recruiting
Markers that predict response to immunotherapy before lung surgery
This study looks for blood or tissue markers that can predict who benefits from immunotherapy given before surgery for non-small cell lung cancer. It may help doctors better choose treatment in the future.
ShanghaiAges 18–80 - NCT06162221RecruitingPhase 1/Phase 2
Study of RAS inhibitors for advanced RAS-mutated lung cancer
This trial tests new drugs that target specific RAS mutations in advanced non-small cell lung cancer. It's for people whose cancer has a KRAS G12C, G12D, or other RAS mutation and who have already tried standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT07405931Recruiting
Managing chemo side effects with phone calls and a smartphone app
This study tests whether checking in by phone or smartphone app can help manage chemotherapy side effects. If you are starting a new chemo for stomach, lung, breast, or colon cancer, this program may support you from home.
BusanAges 19 years+ - NCT07408635RecruitingPhase 2
New Immunotherapy Plus Chemotherapy Before Lung Cancer Surgery
This trial tests a new combination of an immunotherapy drug (IBI363) plus chemotherapy before surgery in people with Stage III lung cancer that can't be removed at first. The goal is to shrink the tumor so it can be surgically removed.
ShanghaiAges 18 years+ - NCT07412327Recruiting
Proton therapy for early stage lung cancer
This trial tests a precise form of proton radiation for people with early stage lung cancer who cannot have surgery. It aims to see if this treatment is effective and safe.
Guangzhou, GuangdongAges 18 years+ - NCT07428044RecruitingPhase 2
Trastuzumab Deruxtecan for HER2-mutant lung cancer before surgery
This trial tests a targeted drug, trastuzumab deruxtecan, for people with non-small cell lung cancer that has a specific HER2 gene change. The treatment is given before surgery to shrink the tumor and make it easier to remove.
Ann Arbor, MichiganAges 18 years+ - NCT07436598Recruiting
3D modeling before lung surgery to predict lung function
This trial uses 3D models from your CT scan to help doctors predict how well your lungs will work after surgery. It is for people having a certain type of lung surgery (VATS) to remove part of a lung.
TaipeiAges 18–80 - NCT07460999Recruiting
Singing training after lung cancer surgery
This trial tests if singing training twice a week can help with ongoing symptoms like shortness of breath or fatigue 6 to 18 months after surgery for early-stage lung cancer.
CopenhagenAges 18 years+ - NCT06060613RecruitingPhase 1/Phase 2
OBX-115 cell therapy for advanced melanoma or lung cancer
This trial tests an experimental cell therapy called OBX-115 for people with advanced melanoma or non-small cell lung cancer that has not responded to standard treatments. The therapy uses your own immune cells to fight the cancer. The study aims to see if it is safe and effective.
Los Angeles, CaliforniaAges 18 years+ - NCT07499674RecruitingPhase 3
A lung cancer surgery study to test a special imaging dye
This trial tests a dye called abenacianine (VGT-309) that may help surgeons see cancer more clearly during lung surgery. It looks at whether the dye is safe and effective for identifying cancer in people having surgery to remove a lung lesion or mass.
Duarte, CaliforniaAges 18 years+ - NCT07505173RecruitingPhase 2
Targeted radiation plus osimertinib for brain metastases from EGFR-mutant lung cancer
This trial tests adding a brain-sparing radiation technique to the targeted therapy drug osimertinib for people with EGFR-mutant lung adenocarcinoma that has spread to the brain and is causing symptoms. The goal is to see if this combination can better control the brain tumors while protecting the hippocampus, a key memory area.
TianjinAges 18–75 - NCT07508852RecruitingPhase 1/Phase 2
PET scan for small cell lung cancer diagnosis
This study uses a special PET scan (68Ga-PFD3) to take pictures of small cell lung cancer tumors. The goal is to see if this scan can help doctors better diagnose and evaluate the cancer, which may guide treatment decisions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07510724Recruiting
Real-world study of Tislelizumab for lung cancer
This trial collects information on how well the immunotherapy drug Tislelizumab works for different types of lung cancer. It is meant for people whose doctor already decided to prescribe this drug as part of their care.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT07517198RecruitingPhase 1
EXS74539 Study for Advanced Solid Tumors
This is an early-stage study testing a new cancer drug called EXS74539 to find the right dose and see how well it works in people with various advanced solid tumors. The drug may help patients whose cancers have stopped responding to standard treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT07538947Recruiting
Real-time imaging to diagnose lung cancer faster and safer
This trial tests a new camera tool (confocal laser endomicroscopy) that lets doctors see lung tissue in real-time during a biopsy procedure. The goal is to diagnose non-small cell lung cancer more quickly and safely than standard biopsies alone.
NancyAges 18 years+ - NCT07543601Recruiting
Better COPD care for people evaluated for lung cancer
This trial tests whether people being checked for possible lung cancer can also get improved care for a breathing condition called COPD (chronic obstructive pulmonary disease). It focuses on patients whose lung function tests show airflow problems.
VejleAges 18 years+ - NCT07557225Recruiting
New PET Scan for Detecting Multiple Cancer Types
This study tests a new type of PET scan (a specialized imaging test) that may better detect certain cancers by looking for a specific marker found on many tumor types. The scan uses a new tracer called 18F-T2 to help doctors see cancer more clearly.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07558447Recruiting
Studying Tiny Particles to Predict Chemotherapy Nerve Damage
This study looks at tiny particles in your blood to understand and potentially predict nerve damage caused by certain chemotherapy drugs. Researchers will monitor you before, during, and after your cancer treatment to see if these particles can help warn doctors about this common side effect.
MilanAges 18 years+ - NCT07563205Recruiting
Study of Chemotherapy and Amivantamab for Advanced Lung Cancer
This study follows patients with advanced lung cancer (a type called non-small cell lung cancer) who are receiving a combination of chemotherapy and a drug called amivantamab. Researchers want to understand how well this treatment works and track your health outcomes over time.
Aix-en-ProvenceAges 18 years+ - NCT07564557Recruiting
Guided surgery for small deep lung cancers
This trial tests a new surgical technique to remove small, early-stage lung cancers that are located deep within the lung tissue. The goal is to remove only the affected area while preserving as much healthy lung as possible.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07572773Recruiting
Lung cancer screening program for current and former smokers
This program offers lung cancer screening (using imaging tests) for people aged 50–77 with a significant smoking history. Early detection can help catch lung cancer at a more treatable stage.
Iowa City, IowaAges 50–77 - NCT07586826RecruitingPhase 2
Romiplostim N01 plus ATRA for low platelets after cancer treatment
This trial tests a combination of two drugs (romiplostim N01 and ATRA) to help raise platelet counts in people whose platelets dropped after chemotherapy for gynecologic, breast, or lung cancer—even though their cancer is now gone. Low platelets can cause bleeding problems, so this treatment aims to help your body make more platelets.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for lung cancer?
- Yes. Clin2 currently lists 2,039 recruiting lung cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.