Clinical trials
Malignancy clinical trials
Below are recruiting malignancy clinical trials, each written for real people, not researchers. We’re tracking 1,586 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02534649Recruiting
Drug-matching trial for adults with cancer DNA changes
This trial looks for the specific DNA or tumor changes in your cancer and then matches you to a targeted drug plan. It’s meant for people with early cancer that has not already been treated in this study.
BayonneAges 18 years+ - NCT02838602Recruiting
Carbon beam radiation vs standard radiation for resistant tumors
This study compares carbon beam radiation with standard radiation for tumors that are less likely to respond to usual radiation. It aims to see whether carbon beams can improve control of the cancer while keeping side effects manageable.
AmiensAges 18 years+ - NCT02754544Recruiting
Brain mapping during tumor surgery while you are awake
This study uses special recording sensors during brain tumor surgery to map the brain areas that control movement and speech. It may help the surgical team protect these key functions while removing the tumor.
Houston, TexasAges 18 years+ - NCT02457962Recruiting
Registry study of outcomes from Mayo radiation treatments
This study collects information about how patients do after radiation treatment and stores some biological samples for future research. It includes people treated at Mayo Clinic Rochester for a cancer-focused (curative) course of radiation.
Rochester, MinnesotaAges Any age - NCT02884375Recruiting
Study for people 70+ with cancer and geriatric care review
This trial enrolls people age 70 or older who have been diagnosed with cancer and are being referred to a geriatrician for a health and care needs review. It tests whether this geriatric assessment and related care approach is useful for elderly cancer patients.
CréteilAges 70 years+ - NCT02835911Recruiting
Lymphoma patient study for people living near Malawi’s main hospital
This is a study that enrolls people with suspected or confirmed lymphoma who come to Kamuzu Central Hospital. It aims to collect lymphoma information (including optional genetic testing of tumor samples) to better understand the disease in Malawi.
LilongweAges birth–99 years - NCT02429687RecruitingPhase 3
Testing two chemo regimens for ovarian germ cell tumors
This Phase 3 trial compares two different chemotherapy approaches for women with ovarian sex cord–stromal germ cell tumors. It aims to see which treatment works better and is safer for newly diagnosed stage IIA to IVB disease after surgery.
Jinan, ShandongAges 14–65 - NCT02429700RecruitingPhase 3
Chemo comparison for certain ovarian tumors after surgery
This Phase 3 trial tests two chemotherapy regimens (TC vs BEP) for women with malignant sex cord-stromal tumors of the ovary. It aims to see which treatment works better after you’ve had initial surgery to diagnose and/or remove tumor.
Jinan, ShandongAges 14–65 - NCT02464696Recruiting
Noninvasive breathing support to avoid tube breathing in cancer
This trial studies a mask-based breathing treatment (noninvasive ventilation) for people with cancer and serious breathing trouble, to see if it can prevent the need for intubation (putting a breathing tube in). If you qualify, the goal is to help you breathe better without invasive airway support when possible.
Houston, TexasAges 18 years+ - NCT02508038RecruitingPhase 1
Test CD19+ depleted donor transplant for hard childhood cancers
This Phase 1 study tests a special type of half-matched (haploidentical) stem cell transplant plus medicines, aiming to reduce cancer relapse after transplant. It may help children and teens with certain leukemia/lymphoma or specific solid tumors who do not have a fully matched donor or whose best options are limited.
Madison, WisconsinAges 7 months–21 years - NCT02800486RecruitingPhase 2
Targeted antibody plus repeat radiation for recurrent brain tumors
This trial studies giving cetuximab (a targeted antibody) directly into an artery along with repeat radiation to treat certain recurring or treatment-resistant brain tumors. It may help by delivering the drug more directly to tumor areas and testing whether this approach can control the disease after it comes back.
New York, New YorkAges 18 years+ - NCT02828202Recruiting
Melanoma patient follow-up study for multiple tumor stages
This study follows adults with certain melanoma stages to better understand the disease over time. You may be asked to share tissue samples (if available) so researchers can study tumor biology and track outcomes.
AmiensAges 18 years+ - NCT02847559RecruitingPhase 2
Electric field therapy plus bevacizumab for recurrent meningioma
This trial tests whether using an electric-field treatment delivered to the brain, along with a cancer medicine called bevacizumab, can shrink or control recurrent (returned) or progressive grade 2–3 meningioma. It’s designed for tumors that can’t be fully cured with surgery and standard treatments, and aims to slow tumor growth and improve outcomes.
Santa Monica, CaliforniaAges 18 years+ - NCT02861898RecruitingPhase 1/Phase 2
Cetuximab delivered into the brain tumor artery for new glioblastoma
This Phase 1/2 study tests whether giving cetuximab directly into the artery that feeds the brain tumor can help people with newly diagnosed glioblastoma. It aims to target the tumor more precisely while checking safety and early signs of benefit.
New York, New YorkAges 18 years+ - NCT03314974RecruitingPhase 2
Stem cell transplant study for blood cancers
This Phase 2 study tests a strong (myeloablative) stem cell transplant using donor stem cells (allogeneic transplant) for certain blood and bone marrow cancers. The goal is to see how well this approach works and whether it can improve outcomes for people who need transplant-level treatment.
Minneapolis, MinnesotaAges Up to 60 years - NCT03270059RecruitingPhase 2
MRI with special contrast to study brain and other CNS problems
This trial tests whether two special MRI contrast medicines—gadolinium and ferumoxytol—can better diagnose problems in the brain or central nervous system. It may help doctors identify what’s causing symptoms or abnormal brain findings.
Portland, OregonAges 10 years+ - NCT02970045Recruiting
USC care program for cancer patients enrolled at Norris
This trial is part of a cancer care program for people receiving outpatient or inpatient care at USC Norris. It helps enroll patients into the program’s care and research paperwork, with consent available in English or Spanish.
Los Angeles, CaliforniaAges 18 years+ - NCT07244835RecruitingPhase 1
A study of DEG6498 for advanced solid tumors
This trial tests a new drug, DEG6498, for people with advanced solid tumors that have not responded to other treatments. It may be an option if your cancer has a BRAF mutation or is a type of liver cancer called HCC.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06897137Recruiting
Improving quality of life measurement in young cancer survivors
This study aims to better understand how cancer affects the quality of life of teens and young adults (ages 15–39). You will fill out questionnaires about your physical and emotional well-being.
Winston-Salem, North CarolinaAges 15 years+ - NCT02688517Recruiting
Tests tumor genomics using blood and stored tissue
This study looks at the genetic information (DNA) from your blood and from saved tumor tissue to better understand certain cancers, especially rare cancers with a poor outlook. It may help researchers learn why these cancers behave the way they do and guide future treatments.
Brick, New JerseyAges 1 year+ - NCT02315599Enrolling by invitation
Follow-up for delayed side effects after gene-cell therapy
This study checks people for delayed side effects after receiving gene-based cell therapy from the NIH. It helps doctors learn what problems may happen later and how to monitor them safely.
Bethesda, MarylandAges 1–99 - NCT02473757Enrolling by invitation
Follow-up program for adults previously treated with CAR T
This is a follow-up study for people age 18 or older who previously took part in a CAR T-cell gene therapy trial. It helps researchers check your health over time after that treatment and supports long-term safety and outcomes tracking.
Bethesda, MarylandAges 18 years+ - NCT02092155Enrolling by invitation
Testing fluid biomarkers from a chest drain in pleural effusion
This trial studies specific markers (biomarkers) found in fluid from a chest drain to better understand pleural effusions (fluid around the lungs), especially when fluid keeps coming back after treatment. You may be helped by contributing to research that could improve how these effusions are diagnosed and managed.
Baltimore, MarylandAges 18–99 - NCT00870129Recruiting
MRI mapping to plan radiation for certain brain tumors
This study uses MRI scans to find higher-risk areas in certain brain and other solid tumors and help plan radiation treatment. It also looks for changes in tumor “metabolites” (chemicals in the tumor) that may relate to how the tumor behaves.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for malignancy?
- Yes. Clin2 currently lists 1,586 recruiting malignancy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malignancy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malignancy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.