Clinical trials
Mechanically Ventilated ICU Patients clinical trials
Below are recruiting mechanically ventilated icu patients clinical trials, each written for real people, not researchers. We’re tracking 126 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07150637Enrolling by invitation
Predicting muscle weakness in children on a breathing machine
This study aims to predict muscle weakness that can happen to children on breathing machines in the ICU. It could help doctors start treatments earlier to prevent this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT06184945Recruiting
Study of ICU staffing and support strategies
This study looks at how different staffing and support strategies may help patients who need a breathing machine in the ICU. Researchers want to see if these approaches can improve care and recovery.
Iowa City, IowaAges 19 years+ - NCT06542107Recruiting
Weaning from a breathing machine after brain injury
This study looks at the best way to help people with a recent brain injury come off a breathing machine (ventilator). It aims to improve the weaning process and reduce time on the ventilator.
Nanjing, JiangsuAges 18 years+ - NCT07150650Enrolling by invitation
Biomarkers for ICU weakness in children on breathing machines
This study looks for early warning signs (biomarkers) of muscle weakness that can happen in children who need a breathing machine for more than a few days. If your child is in the PICU on a ventilator for at least 3 days, this team may be able to test for clues that help prevent or manage this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT02735707RecruitingPhase 3
Adaptive trial for severe pneumonia care in intensive care
This study tests ways to improve treatment for adults with severe pneumonia that lands them in the ICU, adjusting the plan as results come in. It may help your care team find better treatments for lung infection and breathing/heart support needs.
Jacksonville, FloridaAges 18 years+ - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT06499389Recruiting
Breathing muscle therapy for hard-to-wean ICU patients
This study tests a special breathing therapy for intensive care patients who are having trouble coming off the ventilator. If you have weak muscles or a weak cough, the therapy aims to strengthen your breathing so you can recover faster.
Lyon, FranceAges 18 years+ - NCT06479655RecruitingPhase 4
Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Kota Bharu, KelantanAges 18 years+ - NCT07219069Recruiting
Brain monitoring in ICU patients on a ventilator with sedation
This study is testing a special monitor (BIS) that tracks brain activity in patients on breathing machines and sedation. The goal is to see if it helps doctors provide better sedation care.
Cypress, TexasAges 18 years+ - NCT05160987Recruiting
Sedation choice for ICU patients on breathing machines
This study compares two sedation medicines—remimazolam vs midazolam—for very sick ICU patients who are on a breathing machine. It looks at whether one sedative works better or is safer for keeping patients comfortable while they’re critically ill.
Guangzhou, GuangdongAges 18–80 - NCT06454006Recruiting
Light therapy for patients on breathing machines
This study tests a light therapy (called PBMT-sMF) on people in the ICU who need a breathing machine. It aims to see if the treatment helps muscles and recovery.
Porto Alegre, Rio Grande do SulAges 21 years+ - NCT06999603RecruitingPhase 2
Inhaled study drug for virus infections on ventilators
This study tests an inhaled study drug (SNG001) for adults on a breathing machine in the ICU due to a viral lung infection. The goal is to see if the drug can help patients recover faster.
Sacramento, CaliforniaAges 18 years+ - NCT07146698Recruiting
No sedation vs. daily sedation breaks for COPD patients on a ventilator
This trial compares not using sedation at all versus daily breaks in sedation for people with COPD who are on a breathing machine (ventilator) in the intensive care unit. It aims to see if one approach leads to better outcomes, such as shorter time on the ventilator.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT06702813Recruiting
High-frequency vibration breathing treatment for ICU patients
This trial tests a device called MetaNeb that delivers high-frequency vibrations to help clear mucus and open collapsed air sacs in the lungs. It is designed for patients in the ICU who are awake, alert, and have trouble breathing or need extra oxygen.
Shanghai, Shanghai MunicipalityAges 1.5 years–80 years - NCT07177183Recruiting
Low creatinine as a sign of longer breathing tube use
This study looks at whether low blood creatinine levels can help predict which patients will need a breathing machine for a long time or have trouble coming off it. If you are under 18 and in a post-ICU care unit, you may be able to join.
BrnoAges 18 years+ - NCT06452797Recruiting
ICU Staff Predictions for Long-Term Ventilator Patients
This study asks ICU doctors, nurses, or other providers to give their best guess about what will happen to a patient who has been on a breathing machine for two weeks. The goal is to learn how healthcare teams think about recovery.
Chicago, IllinoisAges Any age - NCT06330610Recruiting
Intermittent tube feeding for organ failure in the ICU
This trial tests if giving tube feeding at certain times of day, instead of continuously, helps people on breathing machines recover from organ failure faster. It is for patients who need a breathing tube and are receiving medicine to support their blood pressure.
Rouen, FranceAges 18 years+ - NCT07162948Recruiting
Home monitoring technology for ICU recovery
This study tests a smart technology box that helps monitor your health at home after a stay in the ICU. It may help you and your doctors keep track of your recovery more easily.
Leiden, South HollandAges 18 years+ - NCT06042621Enrolling by invitation
Improving communication in the ICU for patients, families, and staff
This study looks at how doctors, nurses, and other healthcare team members talk with patients and their families in the intensive care unit (ICU). It aims to improve understanding and support for everyone involved.
Chicago, IllinoisAges 18 years+ - NCT04658498Recruiting
Respiratory muscle training to help patients come off the ventilator
This trial studies whether exercises for breathing muscles can help people who are having a hard time coming off a breathing machine in the ICU. It may help you breathe with less ventilator support once your body is stable enough.
LeuvenAges 18 years+ - NCT07052604Recruiting
Antibiotic treatment for a rare pneumonia in ICU patients
This study looks at how well antibiotics work for pneumonia caused by a specific bacterium (Stenotrophomonas maltophilia) in patients who are on breathing machines in the intensive care unit (ICU). It will help doctors choose the best treatment.
Saint-Denis, FranceAges 18 years+ - NCT07070843Recruiting
Comparing two eye care methods for ICU patients on ventilators
This study compares two different ways of caring for the eyes of intensive care patients on breathing machines. It aims to find which method better prevents eye problems like dryness or infection.
Istanbul, IstanbulAges 3 weeks+ - NCT06977555Enrolling by invitation
Talking with ICU patients on a breathing machine
This study looks at how nurses and doctors communicate with patients who are awake but on a breathing machine (ventilator) in the intensive care unit (ICU). The goal is to improve communication and make the experience better for patients.
OsloAges 18 years+
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Common questions
- Are there clinical trials for mechanically ventilated icu patients?
- Yes. Clin2 currently lists 126 recruiting mechanically ventilated icu patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanically ventilated icu patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanically ventilated icu patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.