Clinical trials
Medication Safety clinical trials
Below are recruiting medication safety clinical trials, each written for real people, not researchers. We’re tracking 408 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05539859Recruiting
Brain bleed surgery trial using endoscope for deep brain bleeding
This trial tests whether a minimally invasive brain surgery using an endoscope can improve outcomes for people with a deep brain bleed. It also studies the safety of this approach compared with standard care.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06364553Recruiting
Metal stent for swallowing problems from cancer
This study tests whether a metal tube (stent) placed in the esophagus can safely improve swallowing in people whose cancer blocks the food pipe and cannot be cured. It may help you eat and drink more comfortably.
Rotterdam, South HollandAges 18 years+ - NCT06423690Recruiting
Safety study of the EAS1 system for small lung tumors
This study tests a new system called EAS1 for people with early-stage lung cancer who are already scheduled for surgery. The goal is to see if the device is safe and works well, and it may offer a less invasive way to remove small lung tumors.
Kfar SabaAges 18–80 - NCT07453342Recruiting
Safety of immunotherapy side effects and restarting treatment
This study looks at patients who had side effects from cancer immunotherapy (checkpoint inhibitors). The goal is to understand those side effects and whether it is safe to restart immunotherapy after they resolve.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06660329Enrolling by invitationPhase 4
Tofacitinib for hard-to-treat Blau syndrome
This study tests if the drug tofacitinib (a JAK inhibitor) can help people with Blau syndrome whose symptoms did not improve with other treatments. Blau syndrome is a rare genetic condition that causes inflammation in the skin, joints, eyes, and other organs.
BeijingAges birth–18 years - NCT06244628RecruitingPhase 3
Study of Iguratimod for chronic graft-versus-host disease
This trial tests an experimental drug called Iguratimod for people with chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It aims to see if the drug can safely control cGVHD symptoms when other treatments haven't worked well enough.
Xuzhou, JiangsuAges 18–60 - NCT05369351RecruitingPhase 2
Mirabegron for brain bleeding soon after symptoms start
This trial studies whether mirabegron can improve safety and outcomes after an intracerebral hemorrhage (a type of brain bleeding). Participants start treatment within 72 hours of symptom onset and are monitored for recovery and side effects.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05661643RecruitingPhase 2
Temozolomide for GIST tumors with SDH deficiency
This trial tests how well temozolomide works and how safe it is for people with GIST (a type of stomach/intestine tumor) that is SDH-deficient and has no KIT or PDGFRα mutations. It may help by targeting tumor DNA repair weakness seen in this SDH-deficient subtype.
Seoul, SeoulAges 20 years+ - NCT06259409RecruitingPhase 1
Reggenn therapy system safety study for back pain
This trial tests a new treatment system for people with a slipped vertebra (spondylolisthesis) or worn-out discs (degenerative disc disease) causing back or leg pain. The goal is to see if the treatment is safe.
Kansas City, KansasAges 18–80 - NCT07142304Recruiting
A study of compression gloves and boots to prevent chemo nerve damage
This trial is testing a wearable device (gloves and boots) that applies gentle compression to your hands and feet during chemotherapy. It aims to prevent or reduce nerve damage (numbness, tingling, pain) that some chemotherapy drugs can cause.
Poway, CaliforniaAges 18 years+ - NCT04592640RecruitingEarly Phase 1
Amniotic stem cell treatment for calciphylaxis
This early-phase study tests a stem cell therapy made from amniotic (placenta) tissue for people with calciphylaxis. If you qualify, the goal is to see whether this treatment is safe and potentially helpful for this rare, painful condition.
Nanjing, JiangsuAges 18–75 - NCT05578053Recruiting
Dalpiciclib for hormone receptor–positive advanced breast cancer
This trial studies whether dalpiciclib can slow down or control advanced hormone receptor–positive breast cancer and assess how safe it is. It’s for people whose cancer has come back in a limited way or spread and can’t be fully cured with surgery or radiation.
Shijiazhuang, HebeiAges 18 years+ - NCT06056115Recruiting
Tislelizumab for lung cancer with brain metastases
This trial tests a drug called tislelizumab for people with advanced lung adenocarcinoma that has spread to the brain but is not causing symptoms. It is for those who have not had prior treatment and whose tumors do not have certain gene changes.
Shijiazhuang, HebeiAges 18–75 - NCT07009236Recruiting
MINIject S+ for open angle glaucoma
This trial tests a tiny implant called MINIject S+ to lower eye pressure in people with open angle glaucoma that isn't well controlled with eye drops. It may be done alone or with cataract surgery.
Santa Rosa de CopánAges 20 years+ - NCT07158658Recruiting
Study of a new skin graft for pressure sores
This trial tests a new skin graft called NeoThelium FT for stage 2 or 3 pressure ulcers on the pelvis or lower leg. It’s for adults whose wounds are not infected and who can use a wound vacuum to help healing.
Bossier City, LouisianaAges 18 years+ - NCT06301399RecruitingPhase 2
Rituximab with prior therapy for advanced liver cancer
This trial tests if adding rituximab to previous cancer treatments can help people with advanced hepatocellular carcinoma (a type of liver cancer) that has stopped responding or caused side effects. It aims to see if this combination is safe and effective.
Tianjin, Tianjin MunicipalityAges 17–79 - NCT05816343RecruitingPhase 2
Orlistat for high triglycerides in people with rare genetic lipid conditions
This Phase 2 trial studies how well and how safely orlistat works over the long term for people who have very high triglycerides linked to rare genetic lipid disorders. It may help lower triglycerides and assess long-term side effects, but you must meet specific genetic, lab, and health requirements.
Dallas, TexasAges 8 years+ - NCT05517291Recruiting
Compare two stent types for blocked thigh artery disease
This trial compares a special drug-coated balloon/stent strategy versus a standard stent approach for people with blocked thigh artery segments. It aims to improve how long the artery stays open and reduces repeat procedures.
BeijingAges 18–85 - NCT07451431RecruitingPhase 4
Mirogabalin for diabetic nerve pain study
This study tests a new pain medicine called Mirogabalin for people with diabetic nerve pain that hasn't gotten better with usual treatments. It aims to see how well the drug works and if it is safe.
DhakaAges 40 years+ - NCT06510205Recruiting
Long-term safety of Mentor breast implants in Chinese women
This study follows women who have Mentor breast implants for 5 years to check their long-term safety. It collects information from your medical records and follow-up visits to monitor how the implants are doing.
ChengduAges 18–100 - NCT03609398RecruitingPhase 2
Phase 2 study of a Rift Valley fever vaccine for safety
This study tests how safe a Rift Valley fever (RVF) vaccine is and how strongly it triggers the body’s immune response. You may be eligible if you are at risk of RVF exposure and your blood test shows you don’t already have strong protection.
Fort Deterick, MarylandAges 18–65 - NCT05938309Recruiting
Safety study of laparoscopic surgery for large stomach GISTs
This study looks at how safe laparoscopic surgery is for stomach GISTs that are 5 cm or larger. If you’re eligible and choose to participate, your team will plan and perform surgery and track safety outcomes.
Fuzhou, FujianAges 18–75 - NCT06948838Recruiting
Improving blood pressure control in safety-net clinics
This study tests if a program to help primary care teams better manage high blood pressure can lower patients' blood pressure. It aims to find ways to improve care for people who get their care at community health centers or similar safety-net clinics.
Boston, MassachusettsAges 18 years+ - NCT06970145RecruitingPhase 1/Phase 2
Anlotinib for recurrent craniopharyngioma
This trial tests if the drug anlotinib can safely and effectively treat recurrent craniopharyngioma, a type of brain tumor. It is for patients whose tumor has come back or grown after previous treatment.
Guangzhou, GuangdongAges 18–75
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Common questions
- Are there clinical trials for medication safety?
- Yes. Clin2 currently lists 408 recruiting medication safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a medication safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a medication safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.