Clinical trials
Metabolism clinical trials
Below are recruiting metabolism clinical trials, each written for real people, not researchers. We’re tracking 1,051 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05077579Recruiting
Alzheimer’s scan study for people with higher body weight
This study uses brain scans (MRI and two special PET scans) to see how Alzheimer’s-related changes show up in people who are overweight or obese, with different blood-sugar and insulin patterns. It may help researchers understand whether body weight and metabolism affect early Alzheimer’s markers in the brain.
St Louis, MissouriAges 40–60 - NCT05047354Recruiting
Study cholesterol metabolism in rare genetic conditions
This study looks at body chemistry (cholesterol-related lab findings) and physical features in people with Smith-Lemli-Opitz syndrome and related rare genetic cholesterol disorders. It may help researchers better understand these conditions and how they affect the body.
Bethesda, MarylandAges 1 day–100 years - NCT05007990Recruiting
Interview study of caregiving networks over a person’s life
This study uses interviews and questionnaires to better understand who makes up a caregiver’s support network when caring for someone with a long-term health condition. Your answers may help researchers understand how caregiving changes over time and across different health situations.
Bethesda, MarylandAges 18–100 - NCT05015881Enrolling by invitationPhase 2/Phase 3
Brain and heart scans in alcohol use disorder
This study uses special brain and heart scans to see how sugar (glucose) is used in people with alcohol use disorder compared with people without it. It may help researchers understand the brain–heart connection in alcohol use disorder.
Philadelphia, PennsylvaniaAges 21–65 - NCT04984226RecruitingPhase 2
Sodium bicarbonate for kidney disease energy and acidity
This trial studies whether taking sodium bicarbonate changes “energy” in cells and improves metabolic acidosis (an acid build-up) in people with moderate-to-severe chronic kidney disease. You may be able to join if your kidney function and blood bicarbonate levels fit their targets and you meet safety rules.
Sacramento, CaliforniaAges 21–85 - NCT04888923Recruiting
How environmental exposures affect your health
This study observes how your body responds to environmental exposures or injuries over time. It aims to understand how different factors like genetics or lifestyle affect your health.
Research Triangle Park, North CarolinaAges 18–90 - NCT04864886Recruiting
Study how immune-related conditions affect metabolism
This study collects blood and other samples to see how the immune system changes “metabolism” (how your body uses energy) in people with immune-related conditions. Your samples may also be stored for future research and could help researchers better understand immune health.
Bethesda, MarylandAges 18–75 - NCT04913805RecruitingPhase 2
Study for HFpEF using heart pressure and energy signals
This Phase 2 study tests how matching heart “filling pressure” and heart muscle “energy use” may improve understanding or treatment of HFpEF, a type of heart failure with preserved pumping strength. You may be asked to have heart scans/tests and follow a study plan if your symptoms and test results fit.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04893226Recruiting
Time-restricted eating for postmenopausal metabolic risk
This trial studies whether limiting when you eat each day can improve blood sugar and other health markers in postmenopausal women with prediabetes or metabolic risk factors. It may help your body’s metabolism if your sleep and daily routine can stay fairly consistent.
Lexington, KentuckyAges 45–65 - NCT04908709Recruiting
MRI-guided proton therapy for high-grade brain tumors in children
This study looks at how metabolism in a child’s brain tumor changes during proton therapy, using special MRI scans. It may help doctors better understand treatment response and tailor care for pediatric high-grade gliomas.
Atlanta, GeorgiaAges Up to 21 years - NCT04841057Enrolling by invitation
Study of blood and stool changes after weight-loss surgery
This study looks at how your body’s metabolism changes after a specific weight-loss surgery (gastric bypass). It may help researchers better understand what to expect and how to tailor care, while requiring blood draws and stool samples before and after surgery.
Columbia, MissouriAges 18–80 - NCT04708431Recruiting
Study of health and wellbeing in people with androgen insensitivity
This study looks at the long-term health and wellbeing of people with androgen insensitivity, a genetic condition that affects how the body responds to androgens (male-type hormones). It may help your care team understand what to watch for over time and improve future guidance for patients and families.
Bethesda, MarylandAges 8–99 - NCT04623502Recruiting
Study of kidney and bladder cancer metabolism during surgery
This study looks at how kidney and bladder (urothelial) tumors use fuel by taking samples during surgery or biopsy. It may help researchers learn what drives these cancers and guide better future treatments.
Dallas, TexasAges 18 years+ - NCT04658303Recruiting
Study of immune and metabolism changes in in-transit melanoma
This trial studies how the immune system and body metabolism change in people with in-transit melanoma (melanoma spread to nearby skin). It aims to understand what’s happening in these lesions and how that information could guide better treatment.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04634591Recruiting
Weight-loss surgery study for people with severe obesity
This trial studies bariatric (weight-loss) surgery and how well it helps people reach and keep a healthier weight. You may qualify if you have severe obesity and have not been able to maintain weight loss with other attempts, and if you can safely follow the study plan.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT04644016RecruitingPhase 2
Cord blood transplant for children and young adults with blood cancers
This Phase 2 trial studies using a cord blood transplant after finding it is risky enough that standard treatment may not be sufficient. It may help certain children and young adults with specific leukemia, lymphoma, and some non-cancer blood/immune or inherited disorders who do not have a well-matched donor available in time.
New York, New YorkAges Up to 21 years - NCT04654000Recruiting
Rheopheresis to treat painful skin damage in calciphylaxis
This trial studies whether a treatment called rheopheresis, added to standard care, can help people with calciphylaxis whose skin wounds are getting worse. It may be considered when ulcers or dead (necrotic) skin appear despite conventional treatment.
AngersAges 18 years+ - NCT04528355Recruiting
Study of hospital data after stem cell transplant for non-cancer illness
This study collects medical information from people with certain non-cancer conditions who receive a stem cell transplant. It may help doctors better understand transplant outcomes and care, since the study focuses on data collection rather than adding new treatment.
Pittsburgh, PennsylvaniaAges 2 months–60 years - NCT04583514Recruiting
Overfeeding study to see how body fat can expand
This trial studies how your body’s fat tissue changes when you eat extra food for 8 weeks. It may help researchers understand why some people gain more weight than others.
Baton Rouge, LouisianaAges 18–42 - NCT04419870Recruiting
Acute infections in people with mitochondrial disease
This study looks at how people with mitochondrial disease respond to acute infections like COVID-19 or the flu. It aims to understand how infections affect the body and to find better ways to care for patients.
Bethesda, MarylandAges 2 months–115 years - NCT04444362Enrolling by invitation
Probacine to protect organs after cardiovascular surgery
This study tests whether a medicine called Probacine can help protect your gut and organs after cardiovascular surgery. If you qualify, you may be asked to take part and follow the study plan to see if complications are reduced.
Beijing, Beijing MunicipalityAges 18–90 - NCT04322734Recruiting
Blood tests study immune and metabolism markers in neurodevelopment
This study looks for biological “signals” in blood—related to the immune system and metabolism—to better understand conditions like autism and other brain or development-related disorders. It may help researchers find markers that could guide future diagnosis or treatment.
Phoenix, ArizonaAges Up to 18 years - NCT04284943Recruiting
Surgery for stomach cancer and diabetes
This trial tests a surgery for early-stage stomach cancer that also aims to improve type 2 diabetes by changing how your body processes food. It might be an option if you have both conditions and are not using insulin.
SeoulAges 20–69 - NCT04227678Recruiting
Study of how fat is handled after eating in rare LPL deficiency
This study looks at how your body processes fatty acids after meals in people with lipoprotein lipase deficiency (a rare genetic condition). It also compares results to people without the condition, which may help researchers understand metabolism and guide future care.
Sherbrooke, QuebecAges 18–75
Hear when a new Metabolism trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for metabolism?
- Yes. Clin2 currently lists 1,051 recruiting metabolism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.