Clinical trials
Metastases clinical trials
Below are recruiting metastases clinical trials, each written for real people, not researchers. We’re tracking 450 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06643884RecruitingPhase 2
Study of eye treatment for cancer that has spread to the eye
This trial tests a new way to treat cancer that has spread to the back of the eye (choroid). The treatment is given directly into the eye, which may help control the tumor and preserve vision.
Palo Alto, CaliforniaAges 18 years+ - NCT06638502RecruitingPhase 1/Phase 2
Testing HRX215 for liver recovery after surgery
This trial tests a drug called HRX215 to see if it is safe and helps the liver recover after surgery to remove colon cancer tumors that have spread to the liver. It is for people who are having either a minor or major liver resection and have a low risk of liver failure.
Baltimore, MarylandAges 18–75 - NCT06335251Recruiting
Radiation therapy for limb cancers
This study looks at how radiation therapy works for cancers in the arms or legs, including primary tumors and cancers that have spread there. It aims to understand the best ways to use radiation for treatment or pain relief.
MilanAges 18 years+ - NCT06552559RecruitingPhase 1/Phase 2
Selinexor plus ICE chemo for brain-involved B-cell lymphoma
This trial tests a new drug, selinexor, combined with standard ICE chemotherapy for patients whose B-cell non-Hodgkin lymphoma has spread to the brain or spinal cord. It aims to see if adding selinexor improves treatment results.
SeoulAges 18 years+ - NCT05950503Recruiting
MRI to assess liver spread from colon cancer
This trial studies how well MRI can evaluate liver metastases (spread to the liver) from colorectal cancer. If you have measurable liver lesions, your MRI results may help doctors better track and plan care.
RomaAges 18–85 - NCT06519591RecruitingPhase 2
New drug combo for stomach cancer with abdominal spread
This trial tests a combination of three drugs (given through a vein and a pill) plus a chemotherapy infusion directly into your belly for stomach cancer that has spread to the lining of the abdomen. It specifically looks at a marker called Claudin 18.2 to see if this treatment works better for people with that marker.
Shanghai, Huangpu DistrictAges 18 years+ - NCT06518057RecruitingPhase 2
Sparing memory during brain radiation for leptomeningeal metastases
This trial tests a special type of radiation that avoids the memory center of the brain (the hippocampus) while treating cancer that has spread to the lining of the brain and spinal cord. It may help reduce side effects on thinking and memory for people with breast or lung cancer.
San Francisco, CaliforniaAges 18 years+ - NCT06501482RecruitingPhase 3
Chemotherapy after liver surgery for colorectal cancer that spread to the liver
This trial tests giving patients a type of chemotherapy called FOLFIRI after they have had surgery to remove colorectal cancer that spread to the liver. The goal is to see if this additional treatment helps prevent the cancer from coming back, for patients who could not have a different chemotherapy before surgery.
Paris, Île-de-France RegionAges 18 years+ - NCT05236946RecruitingPhase 3
Brain radiation timing study for gene-mutated lung cancer
This study compares giving brain radiation right away versus waiting, in people with lung cancer that has an EGFR or ALK gene change and has spread to the brain but causes no symptoms. It aims to see which approach helps control the brain cancer better and keeps quality of life stable.
Mumbai, MaharashtraAges 18–99 - NCT06179602Recruiting
Study of thermal ablation for liver tumors
This study follows patients who are having a procedure called thermal ablation to treat liver tumors. It aims to learn more about how well the procedure works and how safe it is.
LeidenAges 18–110 - NCT06468124Recruiting
Testing treatments on mini tumors for breast cancer that has spread
This trial uses a special lab technique (called organoids) to grow a mini version of your tumor from a biopsy sample. Researchers will test different treatments on these mini-tumors to see which one might work best for you.
LondonAges 18 years+ - NCT06388252Enrolling by invitation
ECT changes in melanoma skin tumors
This study tests how electrochemotherapy (ECT) changes the area around melanoma tumors in the skin. It may help doctors understand why ECT works and who benefits most.
LjubljanaAges 18–100 - NCT06362395RecruitingPhase 3
Very high single-dose radiation for liver tumors using MRI guidance
This trial tests a very high, single dose of radiation guided by MRI to destroy liver tumors that have spread from certain cancers. It may be a good option if you have 1 to 3 liver tumors that are away from sensitive organs and your liver is working well.
Toronto, OntarioAges 18 years+ - NCT06367270RecruitingPhase 2
Chemotherapy spray into the belly for stomach, pancreas, or colon cancer
This trial tests a new way to give chemotherapy – as a fine mist sprayed directly into the belly during a short laparoscopy (keyhole surgery). It is for people whose stomach, pancreas, or colon cancer has spread to the lining of the belly, and who haven't had much chemotherapy before.
Hong KongAges 18 years+ - NCT06339658Recruiting
Comparing two dyes for lymph node surgery in breast cancer
This trial compares two dyes (ICG and blue patent) to see which is better for finding the first lymph node (sentinel node) during surgery in women with breast cancer that has spread to the lymph nodes and who had chemotherapy first.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT06356584RecruitingPhase 2
A drug combination with or without radiation for advanced colorectal cancer
This trial tests a new drug combo (fruquintinib and sintilimab) with or without radiation for people with colorectal cancer that has spread to the liver and has not responded to earlier treatments.
Jinan, ShandongAges 18–75 - NCT06328465Recruiting
MRI for early detection of breast cancer spread
This trial is testing a new way to use MRI scans to find breast cancer that has spread to other parts of the body early. It is for people who have had aggressive breast cancer (HER2 positive or triple negative) and finished treatment with surgery, but still have a higher risk of the cancer coming back.
MilanAges 18–75 - NCT06328686RecruitingEarly Phase 1
Arginine and whole brain radiation for brain metastases
This trial tests whether taking arginine (an amino acid) during whole brain radiation therapy can help people with brain metastases from any type of cancer. It looks at how the treatment affects the body and may improve outcomes.
Atlanta, GeorgiaAges 18 years+ - NCT06315010RecruitingPhase 2
Repotrectinib for lung cancer with brain metastasis
This trial tests a targeted pill called repotrectinib for people with a specific type of lung cancer (ROS1-positive non-small cell lung cancer) that has spread to the brain. The drug aims to shrink brain tumors and control the cancer, especially when brain-focused treatments like surgery or radiation are not needed right away.
GrazAges 18 years+ - NCT05866432RecruitingPhase 2
Dato-DXd for triple-negative breast cancer brain metastases
This trial studies Dato-DXd (an antibody-drug medicine) in people with triple-negative breast cancer that has spread to the brain. It aims to see how well it controls brain tumors when they are newly found or growing after other treatments.
Vienna, State of ViennaAges 18–100 - NCT06287723Recruiting
Blood test for cancer DNA after liver surgery in colorectal cancer
This study uses a simple blood test (liquid biopsy) to look for tiny bits of cancer DNA after surgery for colorectal cancer that spread to the liver. It aims to see if this test can find cancer earlier than standard scans, which may help guide future treatment decisions.
MontpellierAges 18 years+ - NCT06280495RecruitingPhase 2/Phase 3
Targeted drugs plus chemo before surgery for colon cancer with liver spread
This trial tests whether adding two targeted drugs (serplulimab and bevacizumab) to standard chemotherapy before surgery can improve outcomes for people with colorectal cancer that has spread to the liver. It is for those whose cancer has certain genetic features and is considered resectable.
Guangzhou, GuangdongAges 18–75 - NCT06238882Recruiting
Nitroglycerin plus radiation for EGFR-mutant lung cancer with brain spread
This trial tests whether adding nitroglycerin (a medicine that widens blood vessels) to standard whole-brain radiation helps improve treatment for lung cancer that has spread to the brain. It is for people with a specific gene change (EGFR mutation) in their cancer.
Mexico City, Mexico CityAges 18–85 - NCT06250777Enrolling by invitationPhase 2
T-DXd for HER2-mutant lung cancer with brain metastases
This trial tests a drug called T-DXd in people with advanced non-squamous lung cancer that has a specific HER2 gene change (mutation) and has spread to the brain but isn't causing symptoms. The goal is to see if the drug can shrink tumors and help control the cancer.
SeoulAges 20 years+
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Common questions
- Are there clinical trials for metastases?
- Yes. Clin2 currently lists 450 recruiting metastases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metastases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metastases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.