Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 345 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07575529Recruiting
Senior Milk Powder and Gut Health in Healthy Aging
This study tests whether a special milk powder containing beneficial bacteria and fiber (called synbiotics) can improve gut health in adults aged 40–65. You'll use a smartphone app and Apple Watch to track your health and provide samples over several weeks.
SingaporeAges 40–65 - NCT06738329Recruiting
How seaweed additive carrageenan affects gut bacteria
This study tests whether carrageenan, a seaweed-based food ingredient, changes the balance of bacteria in your gut. It could help us understand how common food additives affect digestion and overall health.
Reading, ReadingAges 18–55 - NCT06749483Recruiting
Gut bacteria and infection in intensive care patients
This study looks at how gut bacteria affect severe infections in the ICU. It tests whether the microbiome can be a source of sepsis and a target for treatment. If you are critically ill or a long-term sepsis survivor, you might help find new ways to prevent infections.
Jena, ThuringiaAges 18 years+ - NCT07532629Recruiting
How Gut Bacteria Affect IVF Success in Couples
This study examines how the bacteria in your gut and your partner's gut may affect the success of IVF (in vitro fertilization) treatment. Researchers will collect samples and health information from couples before IVF to see if certain bacterial patterns predict better pregnancy outcomes.
MalmöAges 18–40 - NCT07481578Recruiting
Exercise and gut health study for active men
This study looks at how your training load affects your gut bacteria and how that relates to exercise performance and muscle health. It may help understand overreaching in healthy men.
Leuven, Vlaams BrabantAges 18–45 - NCT04957511Recruiting
Testing gut bacteria in gynecologic cancer patients on immunotherapy
This study looks at how gut bacteria may relate to how well immunotherapy works in people with advanced or returning gynecologic cancer. You may be asked to give stool samples several times so researchers can measure changes in your gut microbiome.
Orlando, FloridaAges 18 years+ - NCT07453212Enrolling by invitation
Food supplement for dry eye caused by meibomian gland issues
This trial tests a food supplement designed to improve dry eye symptoms by targeting the microbiome. It may help if you have dry eye due to meibomian gland problems and are not using contact lenses or certain other eye treatments.
IstanbulAges 18–65 - NCT05412758Recruiting
Breath and blood tests to study stomach and food-pipe cancer
This study looks at how certain “volatile” substances in breath change in people with stomach or food-pipe (oesophageal) cancer, compared with people who have other non-cancer stomach/food-pipe conditions. It may help researchers find better, earlier ways to assess cancer—especially in people who have not started treatment yet.
LondonAges 18–90 - NCT06812091Recruiting
Study on microbiome in children
This study explores the role of the microbiome (the community of bacteria in our bodies) in children's health. It aims to develop new treatments for pediatric diseases.
SeoulAges Any age - NCT07264998Recruiting
Gut bacteria study in breast cancer patients on Abemaciclib
This study looks at how gut bacteria changes in people taking Abemaciclib (a breast cancer drug) and whether that relates to diarrhea. It may help find ways to prevent or manage this side effect.
Wuhan, HubeiAges 18–75 - NCT04658238Recruiting
Dry eye study of the eye microbiome and immune system
This trial looks at how changes in the eye’s normal germs (microbiome) and the immune response may relate to dry eye. It may help researchers better understand what drives symptoms and how to improve care.
BernAges 18 years+ - NCT06903806Recruiting
Gut Microbiome Sampling During Endurance Exercise
This study looks at how endurance exercise affects the bacteria living in your gut. Researchers will collect samples before and after exercise to see what changes. It may help us understand how exercise keeps your gut healthy.
Stanford, CaliforniaAges 18–80 - NCT07184684RecruitingPhase 2/Phase 3
Nasal bacteria transplant for chronic sinusitis
This trial tests if transplanting healthy nasal bacteria from a donor can help people with chronic sinusitis. It aims to restore a healthy microbiome in the nose to reduce symptoms like congestion and discharge.
HelsingborgAges 18 years+ - NCT07066280RecruitingPhase 3
A cream to prevent skin irritation from radiation for breast cancer
This study tests a special cream that may prevent skin irritation (radiation dermatitis) caused by radiation therapy for breast cancer. The cream is made from natural weak acids and aims to protect the skin by keeping the skin's microbiome healthy.
Guangzhou, GuangdongAges 18–70 - NCT07071181Recruiting
Milk-based drinks for better sleep and health
This trial tests whether drinking a milk-based drink every day for four weeks can improve gut health, sleep quality, and heart health. It may be a good option if you have trouble sleeping and are overweight.
Leeds, West YorkshireAges 40–70 - NCT06992986Recruiting
Urine Bacteria in Bladder Cancer vs. Other Conditions
This study compares the bacteria in urine of men with bladder cancer to those with other urinary issues and healthy men. For bladder cancer patients, it looks at differences before a planned surgery to remove the bladder.
RomeAges 50–70 - NCT07024238Enrolling by invitation
Short-chain fatty acid supplement for kidney transplant patients
This study tests whether taking a short-chain fatty acid (a type of fiber-like substance) supplement can improve gut health in people who have had a kidney transplant. It may help keep the transplant working well.
Martin, SlovakiaAges 18 years+ - NCT06954675Recruiting
Ketone drink study: how it affects gut bacteria in healthy adults
This study tests how a ketone ester drink changes the bacteria in your gut. You'll drink the supplement and fill out questionnaires online. It's for healthy adults who want to help researchers understand gut health.
San Francisco, CaliforniaAges 18–40 - NCT06912126Recruiting
The Maggie Project: Exploring vaginal microbiome origins and heredity
This study looks at how the vaginal microbiome is passed between family members or close contacts. If you are a Belgian woman in good health who can join with her mother and another person, you may help researchers understand what shapes this bacteria community.
AntwerpAges 10 years+ - NCT06876935Recruiting
Avocado for healthy growth in Hispanic infants
This study tests if feeding avocado to Hispanic infants when they start solids helps their gut health and development. We need families who are ready to offer avocado regularly for about 6 months, starting when their baby is around 6 months old.
Phoenix, ArizonaAges 3 months–6 months - NCT06741293Recruiting
Improving colorectal cancer early screening with stool tests
This study looks for markers in stool (poop) to detect colorectal cancer early. If you are between 40 and 74, live in the Lisbon area, and don't have certain digestive or cancer conditions, you may help improve screening by providing a stool sample.
Lisbon, Lisbon DistrictAges 40–74 - NCT06738173Recruiting
Gut bacteria test to screen for colorectal cancer
This trial tests a new tool that looks at gut bacteria to help find colorectal cancer earlier. It's for people who already had a positive result on a standard stool test (FIT) as part of a national screening program.
Rome, RMAges 50–74 - NCT06734156Recruiting
Gut microbiome study in colorectal cancer patients
This study looks at how bacteria and other microbes in your gut are linked to colorectal cancer risk and outcomes. By collecting stool samples from people newly diagnosed with colorectal cancer, researchers hope to find patterns that could improve understanding and future treatments.
Lisbon, Lisbon DistrictAges 40–74 - NCT06657001Enrolling by invitation
Personalized nutrition study for gut health
This study uses information from your gut bacteria (microbiome) to create personalized nutrition advice. It is for people with gut conditions like IBD, IBS, or celiac disease, as well as healthy volunteers.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 345 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.