Clinical trials
Microvascular Disease clinical trials
Below are recruiting microvascular disease clinical trials, each written for real people, not researchers. We’re tracking 47 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06070662Recruiting
New MRI test for small heart vessel disease
This study tests a new way to diagnose small blood vessel disease in the heart using an MRI scan during a stress test. It is for people who are already participating in a larger heart imaging study and are scheduled for a catheter procedure.
Leicester, LeicestershireAges 18 years+ - NCT06699420RecruitingPhase 4
Qishenyiqi pill for small vessel heart disease
This trial tests if a Chinese herbal pill called Qishenyiqi can help people with chest pain caused by tiny heart blood vessels that are too tight. It may be an option if standard tests show your heart vessels are mostly clear but your blood flow is reduced.
Jinan, ShandongAges 40–75 - NCT06600178RecruitingPhase 1
Heart medication for women with chest pain and small vessel disease
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
Charlottesville, VirginiaAges 18 years+ - NCT06597851Recruiting
Insulin resistance and heart artery health: a study for chest pain patients
This study looks at how insulin resistance affects tiny heart arteries in people who have chest pain and signs of heart stress on tests, but do not have major blockages in their heart arteries. It aims to understand why some people have heart symptoms even when their main arteries appear clear.
Verona, VRAges 18 years+ - NCT06676137Recruiting
Coronary microvascular disease study in China
This study looks at chest pain caused by tiny blood vessels in the heart that don't show up on standard angiograms. It aims to understand this condition better to help find better care.
ZhengzhouAges 18–85 - NCT06898541Enrolling by invitation
A device to treat chest pain from small heart artery disease
This trial tests a device called the Coronary Sinus Reducer for people with chest pain caused by problems in the small arteries of the heart. The device is placed in a vein near the heart to improve blood flow and reduce symptoms.
RotterdamAges 40 years+ - NCT02180178Recruiting
Heart catheter registry for slow coronary blood flow
This study builds a database of people who are having a coronary angiography (a heart blood-vessel X-ray test). It aims to better understand conditions like slow blood flow in the heart’s small vessels and may help improve how these conditions are diagnosed and treated.
MainzAges Any age - NCT07449325Recruiting
Heart sinus reducer for chest pain from small vessel disease
This trial tests a device placed in a heart vein (the coronary sinus) to improve blood flow and reduce chest pain in people with coronary microvascular dysfunction (small blood vessel disease). It aims to help those who still have symptoms despite taking heart medications.
New Haven, ConnecticutAges 18 years+ - NCT05841199Recruiting
Study heart blood flow during fast heart rates
This study measures how well blood flows through the heart when the heart rate is increased during a heart procedure. It may help doctors better understand coronary (heart artery) blood flow and how to guide treatment when you need angiography or angioplasty.
LondonAges 18 years+ - NCT04612322Recruiting
Study registry for microvascular angina patients
This registry study collects information from adults with microvascular angina (chest pain from small blood vessels in the heart). It may help researchers better understand how to assess and manage this condition over time.
Mainz, RLPAges 18–85 - NCT07761728Enrolling by invitation
Comparing two heart PET scan tracers
This study compares two types of radioactive tracers used during heart PET scans to see if one is better at detecting blocked arteries. Participation involves receiving one of the tracers during your routine scan and may help improve heart disease diagnosis.
Los Angeles, CaliforniaAges 18 years+ - NCT05913999Enrolling by invitation
PET and heart scans during early chemotherapy
This trial studies how a specialized heart imaging test (PET/MPI) changes during the start of chemotherapy for cancer patients. It may help researchers understand whether this monitoring approach detects heart strain early and keeps patients safer during treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT03479580Recruiting
Registry for coronary and small-vessel heart disease in cardiomyopathy
This study enrolls people with certain types of heart muscle diseases to learn how blocked heart arteries and tiny blood vessels affect symptoms and outcomes. It may help researchers better understand these conditions and improve future care.
La TroncheAges 18–100 - NCT07613996Recruiting
Blood Flow Measurement During Heart Imaging
This study examines how a special measurement technique works when blood vessels are dilated during a heart imaging procedure. It may help doctors better assess whether narrowing in your heart arteries needs treatment.
Shanghai, Please SelectAges 18 years+ - NCT05960474Recruiting
Study registry for coronary microvascular disease
This trial is a registry, meaning it mainly collects information about people with coronary microvascular disease. It may help researchers better understand the condition and how it affects daily health and treatment needs.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04606459Recruiting
Device trial for hard-to-treat heart chest pain from small vessels
This trial tests whether a small pressure-reducing device placed in a heart vein (the coronary sinus) can reduce symptoms in people with ongoing chest pain from tiny blood vessel problems. It is for angina that has not improved despite standard heart medicines, and only if special heart tests show reversible reduced blood flow.
Mainz, Rhineland-PalatinateAges 18–85 - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT07359768Recruiting
Testing a noninvasive device for heart disease risk
This trial uses a noninvasive device to examine small blood vessels in people at high risk for heart disease. It may help doctors better understand who needs preventive care.
Stockholm, DanderydAges Any age - NCT06503640Recruiting
Microvascular dysfunction in angina patients
This study tests if chest pain with clear arteries is caused by tiny heart vessel problems. It may help find better treatments for patients whose arteries look normal on angiograms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06393478Recruiting
Southeastern Europe Microcirculation Registry
This study is collecting information about how well the tiny blood vessels in the heart work in people with chest pain. It helps doctors learn more about microcirculation problems and may lead to better treatments.
RijekaAges 18 years+ - NCT07222683Recruiting
How kidney transplant affects heart blood vessel health
This study looks at how receiving a kidney transplant changes the health of small blood vessels in the heart. It may help people with advanced kidney disease understand the benefits of transplant on their heart health.
Boston, MassachusettsAges 18 years+ - NCT06076551Recruiting
Sex differences in small blood vessel problems of the heart
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
SeoulAges 20–80 - NCT06125392Recruiting
New Definition for Small Heart Vessel Disease
This trial studies a condition where small heart vessels don't work well. It looks at new ways to define this problem using a special test that measures pressure and blood flow in a heart artery.
Mainz, Rhineland-PalatinateAges 18–90 - NCT05178914Recruiting
Testing heart pain treatment guided by blood-flow measurements
This study looks at how to personalize treatment for people with angina (chest pain) by measuring how well blood flows through the heart’s small vessels and the main arteries during a procedure. It may help doctors choose the right approach after your coronary angiography (heart artery imaging).
La TroncheAges 18 years+
Hear when a new Microvascular Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for microvascular disease?
- Yes. Clin2 currently lists 47 recruiting microvascular disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microvascular disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microvascular disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.