Clinical trials
Mild Cognitive Impairment clinical trials
Below are recruiting mild cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 410 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05273125Recruiting
Testing mobility and thinking in people with mild cognitive problems
This study looks at how well people with mild cognitive problems can think and move, using brief learning/thinking tests and a walking task. It may help researchers understand changes early enough to guide future care.
LilleAges 65 years+ - NCT06839079Recruiting
Brain training for trauma survivors with head injury
This study tests a cognitive rehabilitation program for people with traumatic brain injury who have also experienced war, violence, or other trauma. It aims to improve memory and thinking skills using exercises and strategies.
Boston, MassachusettsAges 18–65 - NCT02290834Recruiting
Studying brain and thinking changes after chemotherapy in older breast cancer patients
This study looks at how chemotherapy may affect memory and thinking, using thinking tests and possibly brain imaging. It compares older breast cancer patients who do and do not get chemotherapy, plus a group of healthy older adults.
Boston, MassachusettsAges 60 years+ - NCT06709898Recruiting
Returning to work after a stroke
This study looks at how job accommodations can help people return to work after a stroke. It focuses on those who had a stroke within the last year and have some thinking or emotional symptoms.
Helsinki, UusimaaAges 18–68 - NCT05663034Recruiting
Compare CBT-I vs MBTI for sleep and trauma symptoms after TBI
This study compares two types of talk-based therapy to help veterans with long-lasting insomnia after a traumatic brain injury (TBI), and also looks at related post-trauma stress symptoms. It may help you improve sleep and reduce how much these symptoms affect daily life.
Eglin Air Force Base, FloridaAges 18 years+ - NCT05708716Recruiting
Diet and brain training for people after blood cancer
This study tests whether a combined diet plan and structured brain (cognitive) training can improve thinking and memory in people who have had blood cancer. It may help survivors who already have mild-to-moderate thinking problems.
Birmingham, AlabamaAges 21 years+ - NCT07496255Recruiting
Virtual reality for memory help after ICU confusion
This trial tests whether using virtual reality (VR) can help older adults recover their thinking and memory after a serious illness and confusion in the ICU. You may be eligible if you are 50 or older, spent time on a breathing machine, and had delirium in the ICU.
Indianapolis, IndianaAges 50 years+ - NCT07128186Recruiting
AI predicts memory decline in type 2 diabetes
This study uses an AI tool to predict memory problems in people with type 2 diabetes. It may help catch early signs of cognitive decline and guide future care.
Enshi, HubeiAges 40–75 - NCT06986096Recruiting
Brain health through diet and exercise
This study tests whether a healthy lifestyle program—combining nutrition advice and exercise training—can help protect brain health in people with early memory problems. It may be a good fit if you have mild cognitive concerns and are ready to make positive changes.
Bratislava, Bratislava RegionAges 60–80 - NCT07532460Recruiting
Study of brain channels and memory in cocaine users
This research explores how certain brain chemicals (potassium channels) affect memory and thinking in people who use cocaine regularly. The study may help develop better treatments for cocaine use disorder and related thinking problems.
Zurich, Canton of ZurichAges 20–50 - NCT06601465RecruitingPhase 2
Vericiguat for cognitive health in heart failure
This study tests whether the heart failure medication vericiguat can also improve thinking and memory in people with heart failure who have mild cognitive problems. It involves taking vericiguat pills and having brain scans to track changes.
Calgary, AlbertaAges 18 years+ - NCT07731087Recruiting
Stem cell secretion therapy for thinking recovery after stroke
This study tests whether a therapy made from stem cell secretions can help improve memory and thinking after an ischemic stroke. It is for people who had a clot-related stroke in the past 3 months and now have mild to moderate cognitive issues.
Makassar, South SulawesiAges 40–75 - NCT07338682RecruitingPhase 2
L-Arginine for memory in older adults
This trial tests if L-Arginine, a natural amino acid, can improve thinking and memory in adults over 60 with mild to moderate memory problems. You may join if you have no other brain diseases or certain health conditions.
CairoAges 60 years+ - NCT05081596Recruiting
Primary care program for mood and thinking in early Alzheimer’s
This trial tests a psychosocial (talk/behavior/support) program delivered through primary care to improve thinking and depression symptoms in older adults with mild cognitive problems and early Alzheimer’s. It may help if you have early memory/thinking changes plus mild depressive symptoms and you can work with a caregiver or study partner.
White Plains, New YorkAges 60 years+ - NCT07208734Enrolling by invitation
Personalized brain stimulation for memory loss in older adults
This trial tests a personalized brain stimulation treatment for older adults with mild memory or thinking problems caused by Alzheimer's disease. It aims to see if tailored stimulation can improve cognitive function.
Beijing, Beijing MunicipalityAges 50–90 - NCT07042087Recruiting
Brain health lifestyle study: timed eating and mindfulness
This study tests whether a combination of time-restricted eating and mindfulness can help protect brain health in people with early memory concerns. It lasts 9 months and includes regular guidance and support.
BrnoAges 60–80 - NCT07810517Recruiting
Probiotic and fiber supplement for memory in obesity
This study tests a daily supplement (a probiotic called Lactobacillus acidophilus plus a fiber called inulin) to see if it might help improve memory and thinking in adults with long-term obesity and mild cognitive impairment. If you qualify, you would take the supplement or a placebo for a period of time while the study team monitors your cognitive function.
Huixquilucan, State of MexicoAges 30–40 - NCT07658287Recruiting
Virtual reality for older adults in long-term care
This trial tests whether using a virtual reality headset can improve wellbeing for older adults living in long-term care homes. It is designed for people with mild to moderate memory or thinking problems who can use the headset safely.
Québec, QuebecAges 60 years+ - NCT07610655Recruiting
Nerve Stimulation to Aid Recovery After Spine Surgery
This study tests whether a small device that gently stimulates a nerve in your neck can help you recover better after lumbar spine surgery. The device may help reduce confusion, depression, and other thinking problems that sometimes occur after surgery.
Chicago, IllinoisAges 18 years+ - NCT06112639Recruiting
Dance-based rehab for chronic brain conditions
This trial tests a dance exercise program for people with multiple sclerosis or early memory loss. It aims to see if dancing can help physical and mental function safely at home.
BresciaAges 18–85 - NCT07154511RecruitingPhase 1/Phase 2
Tributyrin for Parkinson's with memory problems
This trial tests a supplement called tributyrin to see if it can help with thinking and memory problems in people with Parkinson's disease. You may be able to join if you have both Parkinson's and mild cognitive impairment or dementia.
Ann Arbor, MichiganAges 45 years+ - NCT06417086Recruiting
Acupuncture for Alzheimer's in gene carriers and non-carriers
This trial tests whether acupuncture can help people with Alzheimer's disease. Researchers will compare results in people who carry the APOE e4 gene and those who don't, to see if the treatment works differently.
ShanghaiAges 50–80 - NCT07042633Recruiting
Gamma brain waves and memory in small vessel disease study
This study looks at how brain waves in certain areas may affect memory in people with cerebral small vessel disease. It uses EEG, a safe way to measure brain activity, along with imaging and thinking tests, to understand why some people have memory trouble.
Beijing, Beijing MunicipalityAges 55–75 - NCT06976216RecruitingPhase 3
Study of KarXT plus KarX-EC for Alzheimer's cognitive symptoms
This trial tests a new combination treatment (KarXT plus KarX-EC) to see if it can help with thinking and memory problems caused by Alzheimer's disease. It is for people with mild to moderate Alzheimer's who have a caregiver available.
Long Beach, CaliforniaAges 60–85
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Common questions
- Are there clinical trials for mild cognitive impairment?
- Yes. Clin2 currently lists 410 recruiting mild cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Amnestic Mild Cognitive Impairment
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
- Subjective Cognitive Impairment
- Post-Stroke Cognitive Impairment (PSCI)
- Vascular Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.