Clinical trials
Multivessel Coronary Artery Disease clinical trials
Below are recruiting multivessel coronary artery disease clinical trials, each written for real people, not researchers. We’re tracking 49 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06399692RecruitingPhase 3
Choosing heart bypass or stents for women with heart disease
This study compares two common procedures to improve blood flow to the heart in women with blockages in multiple heart arteries. It aims to find which approach works better for women and may help guide future treatment decisions.
Glendale, CaliforniaAges 18 years+ - NCT06168305Enrolling by invitation
Safety and effectiveness of a GENOSS stent in multiple blocked arteries
This trial tests a new drug-coated stent (GENOSS® DES) for people with blockages in multiple heart arteries. It aims to see how safe and effective the stent is for these patients.
Seoul, SeoulAges 19 years+ - NCT05841199Recruiting
Study heart blood flow during fast heart rates
This study measures how well blood flows through the heart when the heart rate is increased during a heart procedure. It may help doctors better understand coronary (heart artery) blood flow and how to guide treatment when you need angiography or angioplasty.
LondonAges 18 years+ - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05770349Recruiting
Heart failure patients having bypass surgery are studied
This study looks at tiny structures inside heart muscle cells (especially “power stations” in the cells) in people with certain types of heart failure who are getting coronary bypass surgery. It may help researchers better understand what changes happen in the heart and how this could guide future care.
TomskAges 18 years+ - NCT05669222Recruiting
Staged procedure after heart attack using two heart-visual tests
This trial studies whether doing a planned, staged treatment for some artery blockages after a heart attack can improve outcomes. It uses detailed images of the heart arteries and compares results in people who are stable after their initial emergency procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05617599Recruiting
Checks safety of a stent used in complex heart artery disease
This study looks at how safe and effective a specific stent (SUPRAFLEX CRUZ) is when used in real-world care for people with heart artery blockages in more than one artery. Some participants will also be selected if their heart pumping strength is reduced.
Elche, AlicanteAges 18 years+ - NCT02039752Recruiting
Registry for adults with multi-vessel heart disease
This study is a registry that collects information about adults with heart disease affecting more than one vessel. It may help doctors better understand how these conditions are managed over time at Asan Medical Center.
SeoulAges 19 years+ - NCT04968808Recruiting
Find best timing for stent procedure in NSTEMI with multiple vessel disease
This trial compares when to do a stent procedure (PCI) in people with NSTEMI who have disease in more than one coronary artery (non-IRA). It may help doctors choose the safest and most effective timing for treatment to improve outcomes.
GwangjuAges 19 years+ - NCT04795193Enrolling by invitation
Minithoracotomy vs open surgery for multiple blocked heart arteries
This trial compares two types of bypass surgery for people with multiple blocked heart arteries, to see which one better improves quality of life and how well the bypasses stay open. You may be assigned based on your preferences, and the study also tracks heart scan and follow-up results.
Beijing, Beijing MunicipalityAges 25–85 - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT05923489Recruiting
Follow-up angiography after stent placement in high-risk patients
This study checks how routine repeat heart blood-vessel imaging (angiography) after stent placement may help high-risk patients. It is meant for people who had a successful stent procedure and have certain higher-risk heart features.
Hangzhou, ZhejiangAges 18 years+ - NCT06231966Recruiting
High-dose statin combo vs. standard statin for artery disease
This trial compares a high-dose combination of rosuvastatin (a statin) and ezetimibe (another cholesterol-lowering drug) versus a standard rosuvastatin-only approach for people with peripheral artery disease (narrowed leg arteries) or widespread artery disease. The goal is to see which strategy better lowers LDL cholesterol and reduces heart and limb risks.
SeoulAges 19–80 - NCT05936606Recruiting
Personalized blood thinner choice after stent placement
This trial tests whether tailoring anti-platelet (blood clot prevention) treatment can better protect people at higher risk of heart or blood-vessel problems after a drug-eluting stent. It may help prevent future clots and complications, especially in patients with certain high-risk health conditions or complex stent/scar tissue features.
SeoulAges 19–80 - NCT05438121Recruiting
Tests a drug-coated balloon to stabilize clogged heart arteries
This trial studies whether a drug-coated balloon can better treat new, narrowed spots in multiple coronary arteries and “stabilize” the plaque. It may help improve blood flow after a procedure called balloon angioplasty for selected patients.
Ansan-si, Gyeonggi-doAges 18–85 - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT07302659Recruiting
Comparing two aortic clamping methods in off-pump bypass
This study compares two ways to clamp the aorta during off-pump heart bypass surgery to see which is safer for your brain and body. If you are having bypass surgery without a heart-lung machine, you may be able to join.
BeijingAges 18 years+ - NCT06663696Recruiting
A study of Supraflex Cruz stents for multivessel heart disease
This trial is monitoring patients who receive Supraflex Cruz stents in multiple blocked heart arteries. It aims to gather real-world safety and effectiveness data to help improve future care.
SousseAges 18–99 - NCT06273293Recruiting
Post-stent blood flow test with nitroglycerin for multivessel patients
This study tests a new way to measure blood flow after placing a stent, using a very thin wire with a camera. It helps doctors decide if the stent is working well without needing extra medication like adenosine—just a tiny dose of nitroglycerin. You may qualify if you have blockages in two or more heart arteries and are already scheduled for a stent procedure.
AlicanteAges 18 years+ - NCT05812963Recruiting
IVUS vs FFR to guide stents after heart attacks
This trial compares two ways of measuring blood flow inside the heart arteries (IVUS vs FFR) to help decide which non–culprit artery narrowings need a stent after a recent heart attack. It may help doctors choose the best targets for PCI and avoid unnecessary procedures.
GwangjuAges 19 years+ - NCT06506448Recruiting
Studying non-blocked arteries after a heart attack
This study looks at arteries in the heart that aren't the one that caused the heart attack. It uses a special CT scan to understand these arteries better in people who have already had a procedure to open the blocked artery.
Bournemouth, DorsetAges 18–85 - NCT07380919RecruitingPhase 2/Phase 3
Study of ranolazine to prevent heart muscle damage after a heart attack
This trial tests whether a medication called ranolazine can help prevent damage to tiny blood vessels in the heart after a certain type of heart attack (STEMI). You may be eligible if you recently had this kind of heart attack and had a successful procedure to open a blocked artery, but still have other blockages that can be treated with stents.
Catanzaro, ItalyAges 18–80 - NCT07485738Recruiting
Blood flow during bypass surgery and graft recovery
This study looks at how blood flow readings during coronary artery bypass surgery relate to whether the new grafts stay open and how well patients recover. It aims to help improve long-term results for people needing bypass surgery.
New York, New YorkAges 18 years+ - NCT05967663Recruiting
Staged vs same-day heart artery repair after a heart attack
This study compares doing all heart artery procedures right away versus doing part of them later in people who had a heart attack and have blockage in more than one artery. It aims to see which approach is safer and works better after the initial emergency procedure.
ShanghaiAges 18 years+
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Common questions
- Are there clinical trials for multivessel coronary artery disease?
- Yes. Clin2 currently lists 49 recruiting multivessel coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multivessel coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multivessel coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.