Clinical trials
Muscle Pain clinical trials
Below are recruiting muscle pain clinical trials, each written for real people, not researchers. We’re tracking 123 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06780904Recruiting
Dry needling plus stretching for neck pain relief
This study tests if combining dry needling with gentle stretching or muscle energy techniques works better for treating neck pain caused by muscle knots (trigger points). It aims to find a simple, effective way to reduce pain and improve movement.
Kandy, Central ProvinceAges 18–60 - NCT07499687Recruiting
Gentle injection technique for less pain
This study tests a special way of giving a muscle injection (called the TPR technique) to see if it causes less pain and is more satisfying for patients. If you need an injection, this may make the experience more comfortable.
IstanbulAges 18–65 - NCT07547605RecruitingPhase 4
Comparing PRP, Steroid, and Combined Injections for Neck and Shoulder Pain
This study tests three different injection treatments for upper trapezius myofascial pain (a specific type of muscle knot in your neck/shoulder area). Researchers will compare platelet-rich plasma (PRP, made from your own blood), a steroid injection, and a combination of both to see which works best for pain relief.
Kyrenia, KeryneiaAges 18–65 - NCT06511765RecruitingPhase 3
Nerve block for acute lower back pain: a pilot study
This study tests whether a single injection of a numbing medicine (ropivacaine) into the muscles of the lower back can quickly relieve sudden, severe back pain that has lasted less than a week. The goal is to see if this nerve block can help when standard pain pills aren't working.
Saint-HerblainAges 18 years+ - NCT07854028Recruiting
Muscle release techniques for low back pain
This study tests two hands-on treatments—strain counter strain and muscle energy technique—to ease low back pain and improve movement. It may help if you have had low back pain for 3–6 months and have specific tender spots in your back muscles.
Lahore, Punjab ProvinceAges 20–40 - NCT07646899Recruiting
Unstable Loads and Shoulder Movement in Overhead Athletes
This study investigates how using unstable equipment (like a wobbly barbell) affects shoulder blade movement and muscle use during overhead pressing in athletes with shoulder impingement pain. The goal is to understand whether unstable loads might help improve shoulder mechanics and reduce pain in overhead athletes.
TaipeiAges 18–40 - NCT07215104Recruiting
Spinal cord stimulation for chronic low back pain
This trial tests a special type of spinal cord stimulation (called BurstDR) in people with chronic low back pain. If you already have a spinal cord stimulator and it helps your pain, researchers want to see if adding muscle stimulation can provide even more relief.
Charleston, West VirginiaAges 18 years+ - NCT07448857Recruiting
Scapula movement and muscle activity in upper string players with neck pain
This study looks at how the shoulder blade moves and muscles work in violin and viola players who have neck pain. It may help understand why neck pain happens and how to treat it better.
Taipei, TaiwanAges 18 years+ - NCT07760142Recruiting
Electrical stimulation with core exercise for chronic low back pain
This study tests whether adding electrical stimulation to a core exercise program helps relieve chronic low back pain. You would attend two sessions a week for six weeks.
ŞırnakAges 18–55 - NCT06808022Enrolling by invitation
Back exercises before spine surgery
This trial studies whether doing back exercises before spine surgery helps improve recovery. If you are having spine surgery and can safely do physical therapy, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT07740967Recruiting
Collagen and omega supplements for middle-aged women
This study tests whether daily collagen and omega-3 supplements can improve health in healthy middle-aged women. You would take the supplements for a period and have your health measured.
LoughboroughAges 35–65 - NCT07861906Recruiting
Wearable device for jaw muscle pain
This study tests a 24-hour wearable device that tracks jaw muscle activity to better understand and manage chronic jaw muscle pain. You would wear the device for a day to see how your muscles behave, which could help improve future treatments.
Downers Grove, IllinoisAges 18 years+ - NCT07494864Recruiting
Urinary tract health and microbiome study
This study looks at how bacteria and the immune system affect the lower urinary tract. It includes healthy volunteers and people with various urinary conditions, like infections or bladder pain.
Zurich, Canton of ZurichAges 18 years+ - NCT06726239Recruiting
Relaxation exercises before getting up after heart bypass
This study tests whether doing gentle relaxation exercises before getting out of bed can help reduce pain, anxiety, and stress after heart bypass surgery. It may make recovery more comfortable.
Istanbul, IstanbulAges 35–65 - NCT05851196Recruiting
Personalized exercise for recurrent low back pain
This study looks at how back muscle features can help tailor an exercise program for people with recurring, non-specific low back pain. It may help by matching exercises to your specific back function and symptoms.
DiepenbeekAges 18–60 - NCT07600359Recruiting
Physical therapy techniques for sacroiliac joint pain
This study compares two hands-on physical therapy techniques to reduce lower back pain, improve walking, and restore function in people with sacroiliac joint dysfunction (a condition affecting the joint connecting your spine to your pelvis). You'll receive treatment and be assessed to see which technique works better.
Islamabad, Punjab ProvinceAges 25–45 - NCT07611643Recruiting
Treating Jaw Clenching and Facial Pain With a Custom Bite Guard
This study tests whether a custom-made bite guard (called an occlusal splint) can help relieve jaw and facial pain caused by temporomandibular disorders—conditions affecting the jaw joint and muscles. Researchers will monitor how well the treatment works and how it affects your symptoms.
Roma, RomaAges 18 years+ - NCT07860697Recruiting
MRI study of back pain and spine changes
This study looks at MRI images of the lower back to see how body fat, back muscles, and small spine joints relate to long-term back pain. It may help doctors understand back pain better and improve future treatments.
Istanbul, IstanbulAges 18–75 - NCT07555795Recruiting
Game-Based Wearable Sensors to Help Core Muscles and Back Pain
This study tests a wearable belt with sensors and haptic feedback (gentle vibrations) combined with interactive gaming to help strengthen your core muscles and reduce lower back pain. The goal is to make exercise more engaging and effective for chronic back pain.
LondonAges 18 years+ - NCT07543484Recruiting
Tennis Serve Movement Study for Shoulder Pain
This research study examines how your shoulder muscles and joints move during a tennis serve, comparing players with shoulder pain to those without. The goal is to better understand shoulder injuries in tennis and help prevent or treat them.
TaipeiAges 18–40 - NCT05023005Recruiting
Strain-Counterstrain therapy for piriformis muscle pain
This trial tests a hands-on physical therapy technique called “strain-counterstrain” to reduce pain from the piriformis muscle. It may help people whose pain is coming from that specific muscle rather than the low back.
Loma Linda, CaliforniaAges 18–65 - NCT06912438Enrolling by invitation
Emotional release after dry needling for jaw and head pain
This study tests whether a dry needling technique (trigger point needling) can help release emotional tension and reduce pain from muscle knots in the head and neck. It may be a good option if you have jaw or headache pain related to muscle tightness.
Tel Aviv, IsraelAges 18 years+ - NCT06840262Recruiting
Nerve surgery for pain after cancer amputation
This study tests two surgical techniques—target muscle re-innervation and regenerative peripheral nerve interfaces—alone or together, to help reduce pain felt in the remaining limb or the missing limb (phantom pain) after amputation for cancer. The goal is to find the best way to manage pain and improve quality of life.
Houston, TexasAges 18 years+ - NCT07385677Recruiting
Comparing a new approach to usual care for lateral elbow pain
This trial tests if a new way of thinking about the nerves and layers in your arm (called TINLL) works better than usual therapy for people with pain on the outside of their elbow. It may help you get better faster.
South Burlington, VermontAges 18 years+
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Common questions
- Are there clinical trials for muscle pain?
- Yes. Clin2 currently lists 123 recruiting muscle pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.