Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,023 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Stanford, CaliforniaAges 18–75 - NCT06207591Recruiting
Brain implant study for locked-in communication
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
UtrechtAges 18–70 - NCT06210009Recruiting
Can a heart-healthy diet help prevent kidney stones?
This study tests whether a special diet (called DASH, similar to one for high blood pressure) can reduce substances in urine that cause kidney stones. If you have had kidney stones and live in the Birmingham area, this diet might help prevent future stones.
Birmingham, AlabamaAges 19–89 - NCT05159466Recruiting
Transplant from HIV-positive donors to HIV-positive recipients
This trial studies whether it’s safe and effective for HIV-positive people to receive organ transplants from HIV-positive donors. It focuses on matching HIV treatment before and after transplant and checking for major complications.
Metairie, LouisianaAges 18 years+ - NCT05783804Recruiting
Early cholesterol-lowering to help reverse artery plaque
This trial studies whether starting strong cholesterol-lowering treatment early can reduce or reverse plaque in the arteries. It may help protect the heart over time, especially for people with inherited high cholesterol.
Amsterdam, North HollandAges 18–50 - NCT04983823Recruiting
Study aims to improve long-term heart effects after COVID
This trial looks at how persistent heart-related changes after a past COVID infection may be affected by study treatments. It mainly seeks people who are stable enough for follow-up visits and heart imaging, and who are not already on the specific heart medications required.
Melbourne, VictoriaAges 50–85 - NCT06203132RecruitingPhase 3
Doravirine vs Dolutegravir for first-time HIV treatment
This study compares two HIV medicines, doravirine and dolutegravir, to see which works better for people who have never taken HIV treatment before. If you qualify, you would be randomly assigned to one of the two medications.
Nova Iguaçu, Rio de JaneiroAges 18 years+ - NCT06192576Recruiting
Long-term safety study of olipudase alfa in children under 2 with ASMD
This study looks at the long-term safety and effects of olipudase alfa in children under 2 years old with acid sphingomyelinase deficiency (ASMD), a rare genetic condition. It aims to see how the treatment works over time and if it is safe for young children.
Chicago, IllinoisAges Up to 2 years - NCT06192719Recruiting
Study of gallbladder cancer, dysplasia, and gallstones
This trial is studying people with gallbladder cancer, abnormal cell changes (dysplasia), or gallstones. It aims to learn more about these conditions, possibly before or after treatment, or before gallbladder removal surgery.
SaltaAges 18 years+ - NCT06188065Recruiting
Eosinopenia and Recovery in Severe COPD Exacerbation
This study is looking at people admitted to the hospital for a severe COPD flare-up. It checks if a low level of eosinophils (a type of white blood cell) in the blood is linked to how quickly you recover from the flare-up.
North ShieldsAges 35 years+ - NCT06182839RecruitingPhase 2
Canagliflozin for advanced kidney disease with MRI study
This trial tests if canagliflozin, a diabetes medication, can help people with very advanced kidney disease or who recently started dialysis. It uses MRI scans to see how the drug affects the heart and kidneys.
Montreal, QuebecAges 18 years+ - NCT06194591Recruiting
Ultrasound treatment for high blood pressure with kidney disease
This trial tests a new ultrasound treatment on the kidney arteries to see if it can safely lower blood pressure in people with high blood pressure and chronic kidney disease. It may help avoid more invasive procedures.
Lausanne, Canton of VaudAges 18–82 - NCT06165341RecruitingPhase 3
Fazirsiran for mild liver scarring in alpha-1 antitrypsin deficiency
This study tests an investigational drug called fazirsiran, which is designed to treat alpha-1 antitrypsin deficiency-related liver disease with mild scarring. The goal is to see if fazirsiran is safe and can improve or slow liver damage in people with the PiZZ genetic type.
Phoenix, ArizonaAges 18–75 - NCT06158854RecruitingPhase 1/Phase 2
Study of etentamig (ABBV-383) for AL amyloidosis
This study tests a new drug called etentamig (ABBV-383) given through a vein to see if it can control disease activity in people with AL amyloidosis who have already tried other treatments. It may help if your disease has progressed or is not responding well to prior therapies.
Miami, FloridaAges 18 years+ - NCT06169852Recruiting
Brain signal study during DBS surgery for Parkinson's
This study looks at brain signals during awake deep brain stimulation (DBS) surgery for Parkinson's disease. The goal is to learn how these signals can help guide the placement of electrodes to improve treatment.
Birmingham, AlabamaAges 18–89 - NCT06170541Recruiting
Comparing heart artery scans for coronary disease
This study tests whether a newer CT scan method can better detect coronary heart disease. You may qualify if your doctor referred you for a heart CT scan.
Baltimore, MarylandAges 21–85 - NCT06177717Recruiting
Lung Health Study for Young Adults
This study looks at how young adults' lungs work over time. It is a research visit where you'll complete breathing and other health tests to help understand lung health in people aged 25–35.
Birmingham, AlabamaAges 25–35 - NCT06179329Recruiting
Comparing two types of heart bypass grafts in women
This trial compares two types of grafts (the radial artery from the arm and a vein from the leg) used in women having heart bypass surgery for the first time. It aims to see which graft works better and stays open longer.
São Paulo, São PauloAges 18–75 - NCT06180356RecruitingPhase 2
Niraparib after surgery for ovarian cancer with limited spread
This trial is testing a second course of niraparib (a PARP inhibitor) after surgery for ovarian cancer that has come back in just a few spots. It aims to see if restarting niraparib can help keep the cancer from coming back again.
A CoruñaAges 18 years+ - NCT06179212Recruiting
Comparing exercise tests for men and women with heart disease
This study compares two different exercise test methods to see which works better for men and women with heart disease. The goal is to find a test that can help doctors design better exercise programs for you.
Ottawa, OntarioAges 18 years+ - NCT06136091Recruiting
Asthma study in select communities using a smartphone app
This study looks at how asthma affects people in certain communities and tests a new way to manage it using a smartphone app. It is for people with long-standing asthma and those without asthma, to compare their health over time.
Aurora, ColoradoAges 6–17 - NCT06141070RecruitingPhase 3
Adding high-dose radiation to standard treatment for advanced lung cancer
This trial tests whether adding a high, focused dose of radiation to the usual first treatment (chemo and/or immunotherapy) can help people with non-small cell lung cancer that has spread to a limited number of spots (up to 5). The goal is to see if this approach improves how well the treatment works.
GothenburgAges 18 years+ - NCT06145035RecruitingPhase 2
Stem cells from cord blood for heart failure
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
Miami, FloridaAges 21–85 - NCT06144606RecruitingPhase 2
KTE-X19 CAR T for MRD+ B-ALL
This trial tests a CAR T-cell therapy called KTE-X19 for people with B-cell ALL that is in remission but still has trace disease (MRD-positive). The goal is to see if this treatment can eliminate the remaining cancer cells and prevent relapse.
Tampa, FloridaAges 18 years+
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,023 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.