Clinical trials
Musculoskeletal Pain clinical trials
Below are recruiting musculoskeletal pain clinical trials, each written for real people, not researchers. We’re tracking 101 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07746284Enrolling by invitation
Understanding knee osteoarthritis through computer modeling
This study looks at how knee osteoarthritis pain works and aims to build a computer model to better understand it. By joining, you may help doctors improve future treatments for chronic knee pain.
Herndon, VirginiaAges 18–99 - NCT07704853Recruiting
Neck joint study for healthy adults 18–35
This study tests a quick neck move (like a chiropractic adjustment) to see how it affects the small joints in your neck. It may help researchers understand how such moves work on healthy tissue.
Fort Myers, FloridaAges 18–35 - NCT04843865Recruiting
Chinese herbal add-on for joint pain from letrozole
This trial studies whether Chinese herbs, used alongside letrozole, can reduce ongoing joint and muscle pain or stiffness in postmenopausal women with hormone-receptor positive breast cancer. It’s mainly for people whose pain started or worsened after beginning letrozole and who have completed cancer treatments.
Bukit Bintang, Kuala LumpurAges 18 years+ - NCT06514716Recruiting
Steroid shot vs. standard procedure for knee arthritis
This study tests whether a corticosteroid shot (a strong anti-inflammatory medicine) into the knee joint works better than the standard GAE procedure for people with knee osteoarthritis. It aims to see which approach provides better pain relief and function.
ZagazigAges 18–80 - NCT06813495Recruiting
ACT for injury prevention in nurses and aides
This study tests a program called Acceptance and Commitment Therapy (ACT) to help nurses and nursing aides prevent injuries at work. If you work in a long-term care facility in specific areas of the US or Thailand, you may be able to join.
Bowling Green, OhioAges 18 years+ - NCT06832046Recruiting
Intranasal fentanyl for pain in pediatric emergencies
This study looks back at children who already received fentanyl nasal spray for pain in the emergency department. It aims to see how well this method worked for treating sudden pain in children.
StrasbourgAges 1–17 - NCT07217821Recruiting
Music and imagery for chronic pain
This study tests a step-by-step approach using music and guided imagery to help people with long-term muscle or joint pain. It's done from home using a device, so you don't need to travel.
Indianapolis, IndianaAges 18 years+ - NCT07241884Recruiting
Plantar fascia embolization with SakuraBead for heel pain
This trial tests a new treatment for plantar fasciitis using tiny beads (SakuraBead) that are injected to block abnormal blood vessels and reduce pain. It may help people with chronic heel pain that hasn't improved with other treatments.
Tashkent, UzbekistanAges 18–75 - NCT07295457Recruiting
Exercise to prevent pain from hormone therapy in breast cancer
This trial tests whether starting a gentle exercise program early can help prevent or reduce joint and muscle pain caused by aromatase inhibitors (a common breast cancer medicine). It is for women with hormone-sensitive breast cancer who are not yet experiencing severe pain from their treatment.
LyonAges 18–75 - NCT07347028Recruiting
Trigger point injections for knee osteoarthritis pain
This trial tests whether injecting medication into muscle knots (trigger points) can reduce knee pain in people with knee osteoarthritis. It may be an option if other treatments haven't helped enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07347041Recruiting
Trigger point injections for hip osteoarthritis pain
This study tests if injecting pain-relieving medication into tight muscle knots (called trigger points) can reduce hip pain from osteoarthritis. It is for people who still have pain despite trying other treatments.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07555873Recruiting
Osteopathic treatment versus physical therapy for neck and head dysfunction
This study compares two hands-on treatment approaches—osteopathic manipulation and physiotherapy—for chronic neck pain, headaches, and dizziness caused by cervical dysfunction. If you qualify, you'll receive one of these treatments and help researchers understand which works better.
Pristina, PejtonAges 18–65 - NCT07310823Enrolling by invitation
Manual therapy for neck-related headaches
This study tests if manual therapy (hands-on treatment) can help people whose headaches start from neck problems. If you have headaches at least once a week and limited neck movement, this trial may be an option.
GizaAges 20–40 - NCT06576570Enrolling by invitation
Improving surgeon ergonomics with AI analytics
This trial uses AI to analyze surgeon posture and movements during acute care surgeries, with the goal of improving ergonomics and reducing physical strain. It may help identify better surgical practices for both surgeons and patients.
Gainesville, FloridaAges 18–99 - NCT05636137Enrolling by invitation
Study links internet habits with pain and body awareness
This study asks high school students about internet use, musculoskeletal pain (pain in muscles and bones), and body awareness (how well you notice your body). It aims to understand whether these things are connected and may help guide future supports for teens.
Muğla, MenteşeAges 15–18 - NCT04251429Enrolling by invitation
Healthy workplace program for public healthcare workers
This trial studies a workplace program delivered by trained peers to improve health in public-sector healthcare facilities. You may be able to join if you are a direct employee of the agency that runs the facility.
Ages 18 years+ - NCT07448857Recruiting
Scapula movement and muscle activity in upper string players with neck pain
This study looks at how the shoulder blade moves and muscles work in violin and viola players who have neck pain. It may help understand why neck pain happens and how to treat it better.
Taipei, TaiwanAges 18 years+ - NCT06715085RecruitingPhase 4
PRGF injections for chronic low back pain
This trial tests whether injections of a blood-based treatment called PRGF can help people with long-term low back pain caused by worn discs. It is for those who haven't gotten relief from standard treatments like medication.
Vitoria-Gasteiz, AlavaAges 18 years+ - NCT07145645RecruitingPhase 3
Comparing topical diclofenac to oral ibuprofen for pain from ankle or knee injuries in children
This study compares a topical gel (diclofenac) applied directly to the injury site versus an oral medication (ibuprofen) taken by mouth to see which works better for treating pain from ankle or knee injuries in children. It may offer a way to relieve pain without a pill.
Calgary, AlbertaAges 6–18 - NCT06123286RecruitingEarly Phase 1
Tart cherry and omega-3s for joint pain from hormone therapy
This study tests whether taking tart cherry and omega-3 supplements can help reduce joint pain and stiffness caused by aromatase inhibitors (a common breast cancer treatment). If you have bothersome joint pain while on this hormone therapy, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT07396246RecruitingPhase 2
Comparing two treatments for hip pain
This trial tests if a new artery-blocking procedure works better than platelet-rich plasma shots for people with chronic hip pain (greater trochanteric pain syndrome) who haven't improved with physical therapy or anti-inflammatory drugs.
GuimarãesAges 18–80 - NCT00051857Recruiting
MRI Study of Muscle and Bone Function
This research study uses MRI scans (a safe imaging tool) to understand how bones, muscles, and joints work. Researchers are looking for both people with muscle or bone injuries and healthy volunteers to compare how the body moves and functions.
Bethesda, MarylandAges 5–95 - NCT07543484Recruiting
Tennis Serve Movement Study for Shoulder Pain
This research study examines how your shoulder muscles and joints move during a tennis serve, comparing players with shoulder pain to those without. The goal is to better understand shoulder injuries in tennis and help prevent or treat them.
TaipeiAges 18–40 - NCT06831838Recruiting
Pain management program for breast cancer survivors with joint pain
This trial tests a cognitive behavioral therapy (CBT) based program to help relieve joint and muscle pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It aims to improve your quality of life and reduce symptoms.
Jacksonville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for musculoskeletal pain?
- Yes. Clin2 currently lists 101 recruiting musculoskeletal pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.