Clinical trials · Boston, MA
Neoplasms clinical trials in Boston
We’re tracking 138 recruiting neoplasms studies with a site in or near Boston — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 2/Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT07222215RecruitingPhase 2
Capacitabine with or without elacestrant for ER+ breast cancer
This trial tests if adding a new oral targeted therapy (elacestrant) to standard chemotherapy (capecitabine) works better than chemotherapy alone for people with a specific type of advanced breast cancer that is hormone-sensitive (ER-positive) and has stopped responding to hormone therapy.
Boston, MassachusettsAges 18 years+ - NCT05786924RecruitingPhase 1/Phase 2
Targeted cancer drug study for RAS/RAF mutation-positive tumors
This Phase 1/2 study tests S241656 (a targeted cancer medicine) in people whose cancers have certain “RAS/RAF” gene changes. It may help shrink tumors or control cancer growth, and also finds the safest dose and best way to use the drug.
Boston, MassachusettsAges 18 years+ - NCT07198945Enrolling by invitation
6 vs 12 month follow-up after large colon polyp removal
This trial compares whether a follow-up colonoscopy at 6 or 12 months is better for people who have had a large polyp (20-50 mm) removed. It will help doctors understand the best timing for surveillance.
Boston, MassachusettsAges 18 years+ - NCT04996875RecruitingPhase 2
Bezuclastinib for advanced mast cell disease
This Phase 2 study tests bezuclastinib, a targeted medicine, in people with advanced systemic mastocytosis (including certain advanced forms with blood cancers). It aims to shrink measurable disease and improve symptoms, while helping people who may also need treatment for an associated blood cancer.
Boston, MassachusettsAges 18 years+ - NCT07213791RecruitingPhase 1
Study of a new drug for FAP-positive cancers
This trial tests a new drug (LY4337713) for cancers that have a specific protein called FAP on their surface. It may be an option for people whose cancer has continued to grow after standard treatments.
Boston, MassachusettsAges 18 years+ - NCT07227415RecruitingPhase 1/Phase 2
Study of a new drug for advanced kidney cancer
This trial tests a new drug, PF-08634404, alone or with other cancer treatments, for adults with advanced kidney cancer that has not been treated before. It aims to see if the drug can help shrink tumors or stop them from growing.
Boston, MassachusettsAges 18 years+ - NCT04242095Recruiting
Immunotherapy side effects research study
This study collects blood, stool, and tissue samples from people who have had side effects from immunotherapy (a type of cancer treatment that helps your immune system fight cancer). It aims to learn more about these side effects, so doctors can better manage them in the future.
Boston, MassachusettsAges Any age - NCT04870944RecruitingPhase 1/Phase 2
CBL0137 for children with advanced solid or brain tumors
This early-phase study tests CBL0137 in children and teens whose cancer has come back or is not responding to treatment. It is also for some specific hard-to-treat brain tumors, to see if the drug is safe and can work against the cancer.
Boston, MassachusettsAges 1–21 - NCT03113643RecruitingPhase 1
SL-401 with standard drugs for hard-to-treat blood cancers
This Phase 1 study tests SL-401, given with azacitidine and sometimes venetoclax, to treat acute myeloid leukemia (AML), high-risk myelodysplastic syndrome (MDS), or blastic plasmacytoid dendritic cell neoplasm (BPDCN). It aims to find a safe dose and see whether the combination can improve blood cancer control.
Boston, MassachusettsAges 18 years+ - NCT00843375Recruiting
Testing stool samples to find early colon cancer and polyps
This study checks stool samples to see how well stool tests can detect early colon cancer and precancerous growths called adenomas. If you qualify, you’ll collect stool samples for a lab test (FIT) and sometimes this helps sort who should get follow-up testing.
Boston, MassachusettsAges 18 years+ - NCT04548817Recruiting
Registry for neurocutaneous and brain melanocytosis
This trial is a registry that collects information from people with certain pigment-related conditions affecting the skin and/or the brain. It helps doctors better understand the condition and may improve future care.
Boston, MassachusettsAges Any age - NCT06001788RecruitingPhase 1
Ziftomenib for relapsed or refractory acute myeloid leukemia
This trial tests a new drug combination called ziftomenib for people whose acute myeloid leukemia (AML) has come back or hasn't responded to treatment. Researchers will check how safe it is and what side effects happen.
Boston, MassachusettsAges 18 years+ - NCT06941272RecruitingPhase 1/Phase 2
Study of patritumab deruxtecan for children with hard-to-treat solid tumors
This trial tests a new drug, patritumab deruxtecan, in children and adolescents whose rhabdomyosarcoma or hepatoblastoma has returned or not responded to at least one prior treatment. The goal is to see if the drug can shrink tumors or stop them from growing.
Boston, MassachusettsAges 1 month–17 years - NCT03435796RecruitingPhase 2/Phase 3
Follow-up for people treated with gene-modified T cells
This study is a long-term check-in for people who previously received gene-modified T-cell infusions in a related Celgene/Juno/BMS trial. It helps researchers track safety and long-term effects over time.
Boston, MassachusettsAges Any age - NCT05882058RecruitingPhase 2
Dose test of a DLL3 cancer drug for neuroendocrine tumors
This Phase 2 study tests how different doses of BI 764532 affect people with small cell lung cancer or certain other neuroendocrine cancers. It may help shrink tumors and improve symptoms after standard treatments have stopped working.
Boston, MassachusettsAges 18 years+ - NCT06089083Recruiting
Helping gynecologic cancer patients with frailty recover function
This study tests a program to help gynecologic cancer patients who are frail improve their physical function and quality of life during treatment. It aims to see if extra support can help you stay stronger and recover better.
Boston, MassachusettsAges 18 years+ - NCT00756665Recruiting
Study of careful monitoring for prostate cancer
This study follows people with early-stage prostate cancer who choose active surveillance instead of immediate treatment. It aims to see how monitoring with repeat prostate biopsies and follow-up works over time.
Boston, MassachusettsAges 21 years+ - NCT05842603Recruiting
Lifestyle program to help people with MPN move more
This pilot study tests a lifestyle and movement program for adults with certain myeloproliferative neoplasms (MPNs), aiming to improve well-being through safe exercise habits. You may be considered if you have an MPN and at least one heart-related risk factor.
Boston, MassachusettsAges 18 years+ - NCT03858205Recruiting
Low-dose radiation to relieve pain from bone tumors
This trial studies whether low-dose radiation can reduce pain from a specific bone lesion caused by multiple myeloma. It may help people whose main problem is painful bone metastasis, with targeted treatment to the painful spot.
Boston, MassachusettsAges 18 years+ - NCT07059884Recruiting
Exercise program to help people with cancer stay active
This trial tests a distance-based exercise program designed to help people on chemotherapy maintain their physical function and prevent disability. It is for patients with certain cancers who are working full-time and can participate in moderate physical activity.
Boston, MassachusettsAges 18 years+ - NCT04024761RecruitingPhase 1
NK cell therapy for leukemia relapse after transplant
This Phase 1 study tests whether an infusion of special immune cells (NK cells) from a donor can help control leukemia or related blood cancers that come back or do not fully go away after a stem cell transplant. It also uses short chemotherapy to “make space” for the NK cells to work, and IL-2 to help them function.
Boston, MassachusettsAges 12 years+ - NCT06034002RecruitingPhase 1
Study of INCA033989 for myeloproliferative neoplasms
This trial tests a new drug, INCA033989, alone or with ruxolitinib for people with certain blood cancers called myeloproliferative neoplasms (MPNs). It may help those with a specific genetic change (CALR mutation) who have not had success with other treatments.
Boston, MassachusettsAges 18 years+ - NCT07258836RecruitingPhase 1
Study of a PET imaging agent in healthy people and people with cancer
This study uses a special imaging agent (a radioactive tracer) to see how it works in healthy volunteers and in people with cancer. It may help doctors better understand how cancer behaves and how to target it.
Boston, MassachusettsAges 18 years+ - NCT06465069RecruitingPhase 1
Study of an experimental drug for advanced bladder and other cancers
This trial tests a new drug called LY4052031 for people with advanced or metastatic cancers, especially bladder cancer. The drug aims to slow or stop tumor growth. Doctors will check if it is safe and how well it works.
Boston, MassachusettsAges 18 years+
Hear when a new Neoplasms trial opens near Boston, MA
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Neoplasms trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting neoplasms studies listed above.
- Dana-Farber Cancer Institute · 16 studies
- Beth Israel Deaconess Medical Center · 4 studies
- Brigham and Women's Hospital · 3 studies
- Boston Children's Hospital · 2 studies
- Massachusetts General Hospital · 2 studies
- Beth Israel Deaconess Medical Center/Harvard Medical School
- Boston Medical Center
- Local Institution - 01106
What taking part in a neoplasms study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting neoplasms studies in Massachusetts.
Common questions
- Are there neoplasms clinical trials near Boston?
- Yes. We're currently tracking 138 recruiting neoplasms studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a neoplasms study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a neoplasms trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New neoplasms studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.