Clinical trials
Nephrolithiasis clinical trials
Below are recruiting nephrolithiasis clinical trials, each written for real people, not researchers. We’re tracking 28 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05237063Recruiting
Predicting kidney stone recurrence and complications using precision medicine
This study looks for better ways to predict when kidney stones may come back and what complications might happen. It may help doctors personalize follow-up and prevention plans based on information collected from you.
AmiensAges 18 years+ - NCT06330246Recruiting
Study on gut bacteria for calcium kidney stones
This study looks at whether a specific gut bacteria called Oxalobacter formigenes can help people who form calcium oxalate kidney stones. You will eat a controlled diet and provide samples to see how your body handles oxalate, a substance that can lead to stones.
Birmingham, AlabamaAges 18–70 - NCT06331546Recruiting
Gut oxalate absorption in calcium oxalate stone patients
This study looks at how much oxalate (a substance in many foods) gets absorbed by the gut in people who form calcium oxalate kidney stones. You will eat a controlled diet and provide urine and blood samples over a few days.
Birmingham, AlabamaAges 18–70 - NCT06989320Recruiting
Oxalate production in calcium oxalate stone formers
This study looks at how the body makes oxalate (a natural substance that can form kidney stones) in people who have had calcium oxalate stones. You will eat a special diet and stop supplements for a short time to help researchers understand stone formation.
Birmingham, AlabamaAges 18–80 - NCT07668817Recruiting
Closing the tract after kidney stone surgery
This trial tests two ways of closing the small hole made during surgery to remove large kidney stones. It aims to see which method works better for your recovery.
New York, New YorkAges 18 years+ - NCT04669886Recruiting
Blood test before kidney stone surgery to predict infection risk
This study looks at a blood test done before percutaneous nephrolithotomy (PCNL), a procedure to remove kidney stones. The goal is to see whether results can predict who is more likely to develop infections or strong whole-body inflammation after surgery.
Miami, FloridaAges 18 years+ - NCT05014178Recruiting
Kidney salt imaging scan with MRI
This study uses an MRI scan to look at how your kidneys handle salt (sodium). It may help researchers better understand kidney function in healthy people and in people with chronic kidney disease.
London, OntarioAges 18 years+ - NCT06065852Recruiting
National registry for rare kidney diseases
This study creates a registry to collect health information from people with rare kidney diseases. It aims to improve understanding and future treatments by tracking patient experiences.
Bristol, South WestAges Any age - NCT06469736Recruiting
Comparing two methods for removing kidney stones
This study compares two ways to remove kidney stones: using a scope with a laser to break up stones, versus using the same scope plus a special gel to help remove the pieces. It aims to see if adding the gel makes the procedure more effective and safer.
Munich, BavariaAges 18 years+ - NCT06576661Recruiting
New scope for large kidney stone removal
This trial tests a special scope that measures pressure inside the kidney during stone removal. It may help surgeons make safer decisions for people with large kidney stones.
Kansas City, KansasAges 18 years+ - NCT06635889RecruitingPhase 2
Numbing medicine in bladder after kidney stone surgery
This study tests whether numbing medicine placed directly into the bladder can reduce pain after a ureteroscopy procedure for kidney stones. It may help you feel better and use less pain medication after surgery.
Chicago, IllinoisAges 18 years+ - NCT06653738RecruitingPhase 3
Testing empagliflozin and diet advice for kidney stone prevention
This trial tests if a medication called empagliflozin, combined with personalized diet advice, can help prevent kidney stones from coming back. It may be an option if you've had two or more kidney stone events in the last 10 years and your stones were mostly calcium-based.
AmiensAges 18 years+ - NCT06721975Recruiting
Laser vs laser for kidney stone removal
This trial compares two different lasers used to break up kidney stones during a procedure called flexible ureteroscopy. It may help determine which laser works better and is safer.
San Diego, CaliforniaAges 18 years+ - NCT06862141Recruiting
Bendable vs. regular tube for kidney stone removal
This trial tests a new bendable tube against a standard tube used during kidney stone surgery. It may help people with kidney stones that need to be removed with a flexible scope.
Shebin Elkom, MenoufiaAges 18–70 - NCT06966635RecruitingPhase 4
Potassium citrate for gout treatment
This study tests whether a potassium citrate tablet can help people with gout lower uric acid and prevent flares. It is for adults on stable gout medication who are not having a current flare.
ShanghaiAges 18–70 - NCT06974357Recruiting
Genetic testing for calcium phosphate kidney stone formers
This study looks at genes in people who form calcium phosphate kidney stones. It may help doctors understand why some people make this type of stone.
Iowa City, IowaAges 18–90 - NCT07058402Recruiting
Comparing two kidney stone surgeries for medium stones
This trial compares two different surgeries for removing a single kidney stone that is 2 to 3 centimeters in size. One method uses a flexible scope with a suction tube, and the other uses a small incision in the back. The goal is to see which works better and has fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07087977Recruiting
Comparing laser types for kidney stone removal
This trial tests two different lasers (HoYAG and TFL) used with a device called ClearPetra during a type of kidney stone surgery called mini-PCNL. It may help find which laser works better for people with larger kidney stones.
Kansas City, KansasAges 18 years+ - NCT07124299RecruitingPhase 4
Alpha-blockers before kidney stone surgery: a randomized study
This trial tests whether taking an alpha-blocker medication before a type of kidney stone surgery (flexible ureteroscopy) helps the surgeon insert the ureteral access sheath more easily. Alpha-blockers are drugs that relax certain muscles, possibly making the procedure smoother and safer.
Santo André, São PauloAges 18 years+ - NCT07138872Recruiting
Comparing heart health in kidney stone surgery positions
This trial compares how lying on your stomach versus your back during kidney stone removal affects blood flow and heart function. It may help doctors choose the safest position for you.
IstanbulAges 18–80 - NCT07261995Recruiting
Shock wave vs. laser surgery for kidney stones
This trial compares two procedures to break up a single kidney stone. One uses sound waves from outside the body, the other uses a laser through a small scope. Both aim to help you pass the stone more easily.
Karachi, SindhAges 18–65 - NCT07360353Recruiting
Comparing different types of flexible ureteroscopes for kidney stones
This study compares different types of flexible ureteroscopes used to remove kidney stones. It looks at how well they work and their safety.
CairoAges 18–60 - NCT07435844Recruiting
Spa care for kidney and urinary health in adults
This study tests whether a comprehensive spa program can help adults with chronic kidney or urinary tract conditions like infections, stones, or after surgery. It's designed for patients who have not responded well to standard medications.
Mariánské Lázně, Carlsbad RegionAges 40–70 - NCT05993546Recruiting
Comparing two sheath types for mini kidney stone surgery
This study compares two types of sheaths (tubes) used during a small-incision kidney stone surgery. The goal is to see if a vacuum-assisted sheath works better than the standard one to remove stones.
Cleveland, OhioAges 18 years+
Hear when a new Nephrolithiasis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Nephrolithiasis trials by city
Studies with a site in or near these metro areas.
Nephrolithiasis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for nephrolithiasis?
- Yes. Clin2 currently lists 28 recruiting nephrolithiasis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nephrolithiasis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nephrolithiasis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.