Clinical trials
Nephrolithiasis clinical trials
Below are recruiting nephrolithiasis clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05237063Recruiting
Predicting kidney stone recurrence and complications using precision medicine
This study looks for better ways to predict when kidney stones may come back and what complications might happen. It may help doctors personalize follow-up and prevention plans based on information collected from you.
AmiensAges 18 years+ - NCT06989320Recruiting
Oxalate production in calcium oxalate stone formers
This study looks at how the body makes oxalate (a natural substance that can form kidney stones) in people who have had calcium oxalate stones. You will eat a special diet and stop supplements for a short time to help researchers understand stone formation.
Birmingham, AlabamaAges 18–80 - NCT06331546Recruiting
Study of gut oxalate absorption in calcium oxalate kidney stone patients
This study looks at how your gut absorbs oxalate, a natural substance in many foods that can lead to kidney stones. By eating special diets and pausing certain supplements, researchers can measure your oxalate absorption. This may help find better ways to prevent kidney stones.
Birmingham, AlabamaAges 18–80 - NCT06330246Recruiting
Testing a gut bacteria treatment for calcium oxalate kidney stones
This study tests whether giving a specific gut bacteria can help people with calcium oxalate kidney stones. It looks at whether the bacteria can change how the body processes oxalate, which may reduce stone formation.
Birmingham, AlabamaAges 18–80 - NCT07718802Recruiting
Watching vs surgery for kidney stones in children
This study compares simply watching a kidney stone over time versus having surgery to remove it, in children and teens who have a small, symptom-free stone. The goal is to see which approach leads to better health outcomes.
Irvine, CaliforniaAges 6 years+ - NCT06065852Recruiting
National registry for rare kidney diseases
This study creates a registry to collect health information from people with rare kidney diseases. It aims to improve understanding and future treatments by tracking patient experiences.
Bristol, South WestAges Any age - NCT07874087Enrolling by invitation
Kidney stones in children: risks and causes
This study looks at children who have had kidney stones or a related condition called nephrocalcinosis. It aims to learn why these happen in children and what risks or causes are involved, which may help improve care.
Milan, MilanoAges birth–18 years - NCT07866209Recruiting
Comparing two devices for kidney stone surgery
This trial compares two different tubes used during surgery to remove kidney stones. The goal is to see if one type works better than the other for clearing stones safely.
Antalya, MuratpasaAges 18 years+ - NCT07668817Recruiting
Closing the tract after kidney stone surgery
This trial tests two ways of closing the small hole made during surgery to remove large kidney stones. It aims to see which method works better for your recovery.
New York, New YorkAges 18 years+ - NCT07535281Recruiting
Kidney Stone Surgery Technique and Recovery Study
This study tests a technique during kidney stone removal surgery (RIRS) where the surgeon fully drains the kidney system at the end of the procedure. Researchers want to see if this approach improves how quickly patients recover and reduces complications.
Gandong-gu, Outside U.S./CanadaAges 20–80 - NCT07523074Recruiting
Early vs. delayed shock wave treatment for leftover kidney stones
This trial compares two timing schedules for using shock waves to break up small kidney stones that remain after a surgical procedure. The goal is to find the best time to treat these leftover stones to help them pass naturally and prevent complications.
Banī Suwayf, Beni-Suef GovernrateAges 18–70 - NCT07435844Recruiting
Spa care for kidney and urinary health in adults
This study tests whether a comprehensive spa program can help adults with chronic kidney or urinary tract conditions like infections, stones, or after surgery. It's designed for patients who have not responded well to standard medications.
Mariánské Lázně, Carlsbad RegionAges 40–70 - NCT05014178Recruiting
Kidney salt imaging scan with MRI
This study uses an MRI scan to look at how your kidneys handle salt (sodium). It may help researchers better understand kidney function in healthy people and in people with chronic kidney disease.
London, OntarioAges 18 years+ - NCT07360353Recruiting
Comparing different types of flexible ureteroscopes for kidney stones
This study compares different types of flexible ureteroscopes used to remove kidney stones. It looks at how well they work and their safety.
CairoAges 18–60 - NCT06862141Recruiting
Bendable vs. regular tube for kidney stone removal
This trial tests a new bendable tube against a standard tube used during kidney stone surgery. It may help people with kidney stones that need to be removed with a flexible scope.
Shebin Elkom, MenoufiaAges 18–70 - NCT07261995Recruiting
Shock wave vs. laser surgery for kidney stones
This trial compares two procedures to break up a single kidney stone. One uses sound waves from outside the body, the other uses a laser through a small scope. Both aim to help you pass the stone more easily.
Karachi, SindhAges 18–65 - NCT07138872Recruiting
Comparing heart health in kidney stone surgery positions
This trial compares how lying on your stomach versus your back during kidney stone removal affects blood flow and heart function. It may help doctors choose the safest position for you.
IstanbulAges 18–80 - NCT07124299RecruitingPhase 4
Alpha-blockers before kidney stone surgery: a randomized study
This trial tests whether taking an alpha-blocker medication before a type of kidney stone surgery (flexible ureteroscopy) helps the surgeon insert the ureteral access sheath more easily. Alpha-blockers are drugs that relax certain muscles, possibly making the procedure smoother and safer.
Santo André, São PauloAges 18 years+ - NCT06966635RecruitingPhase 4
Potassium citrate for gout treatment
This study tests whether a potassium citrate tablet can help people with gout lower uric acid and prevent flares. It is for adults on stable gout medication who are not having a current flare.
ShanghaiAges 18–70 - NCT07087977Recruiting
Comparing laser types for kidney stone removal
This trial tests two different lasers (HoYAG and TFL) used with a device called ClearPetra during a type of kidney stone surgery called mini-PCNL. It may help find which laser works better for people with larger kidney stones.
Kansas City, KansasAges 18 years+ - NCT06974357Recruiting
Genetic testing for calcium phosphate kidney stone formers
This study looks at genes in people who form calcium phosphate kidney stones. It may help doctors understand why some people make this type of stone.
Iowa City, IowaAges 18–90 - NCT07058402Recruiting
Comparing two kidney stone surgeries for medium stones
This trial compares two different surgeries for removing a single kidney stone that is 2 to 3 centimeters in size. One method uses a flexible scope with a suction tube, and the other uses a small incision in the back. The goal is to see which works better and has fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06721975Recruiting
Laser vs laser for kidney stone removal
This trial compares two different lasers used to break up kidney stones during a procedure called flexible ureteroscopy. It may help determine which laser works better and is safer.
San Diego, CaliforniaAges 18 years+ - NCT06653738RecruitingPhase 3
Testing empagliflozin and diet advice for kidney stone prevention
This trial tests if a medication called empagliflozin, combined with personalized diet advice, can help prevent kidney stones from coming back. It may be an option if you've had two or more kidney stone events in the last 10 years and your stones were mostly calcium-based.
AmiensAges 18 years+
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Nephrolithiasis trials by city
Studies with a site in or near these metro areas.
Nephrolithiasis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for nephrolithiasis?
- Yes. Clin2 currently lists 31 recruiting nephrolithiasis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nephrolithiasis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nephrolithiasis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.