Clinical trials
Nerve Block clinical trials
Below are recruiting nerve block clinical trials, each written for real people, not researchers. We’re tracking 224 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07306533Recruiting
Menstrual phase and dental pain relief study
This trial tests whether the phase of your menstrual cycle affects how well local anesthesia works for a root canal. It may help dentists give you better pain control based on your cycle.
New Delhi, Delhi(दिल्ली)Ages 18–45 - NCT07350252RecruitingPhase 4
Nerve blocks with local pain relief for knee replacement
This study tests if adding a nerve block to standard local pain relief medicine helps control pain better after knee replacement surgery. It may lead to less pain and faster recovery.
TrelleborgAges 18 years+ - NCT07445386Recruiting
Nerve block for upper abdominal cancer pain
This trial compares two types of nerve blocks to treat severe pain from upper abdominal cancers like stomach, pancreas, or liver cancer. It may be an option if your pain hasn't been controlled with standard treatments.
AnkaraAges 18 years+ - NCT07487649Recruiting
Treatment response in headache from medication overuse
This trial looks at how well people respond to treatment when their headaches are caused by taking too much pain medicine. It may help if you have migraines or tension headaches and you use triptans or NSAIDs often.
EdirneAges 18–65 - NCT07510347Recruiting
Pain relief study for sleeve gastrectomy patients
This study tests if giving pain medicine in a different area of the abdomen can reduce pain after weight-loss surgery. It may help you feel more comfortable after your sleeve gastrectomy.
Shibīn al Kawm, MenofiaAges 20–60 - NCT07512635RecruitingPhase 4
Nerve Block Pain Relief for Minimally Invasive Lung Surgery
This trial tests whether numbing medication injected around nerves in the chest can reduce pain and help patients recover faster after minimally invasive lung surgery. The goal is to improve how you feel after the procedure.
Sanming, FujianAges 18–65 - NCT07532200Recruiting
Pain genes and inflammation in tooth root canal treatment
This research study examines how your genes affect pain and inflammation when you have a painful tooth that needs root canal treatment. By studying these responses, researchers hope to better understand why some people experience different levels of pain during dental procedures.
New Delhi, National Capital Territory of DelhiAges 18–50 - NCT07659145Recruiting
Simulation training for ultrasound-guided nerve block in students
This trial tests if a simulation-based training program helps medical students learn how to perform an ultrasound-guided nerve block (a numbing injection near the sciatic nerve). If you're a medical student, you may join to practice and improve your skills.
Santiago, Santiago MetropolitanAges Any age - NCT07429812Enrolling by invitation
Chitosan-Chlorhexidine Gel for Healing After Tooth Extraction
This trial tests a gel made from chitosan and chlorhexidine to see if it helps heal wounds faster after tooth removal in people with diabetes.
Al KharjAges 20–50 - NCT07324915Enrolling by invitation
Buzzy Bee study for reducing pain during numbing shots in kids
This trial tests if a vibrating cold device called Buzzy Bee can help reduce pain when children receive a numbing shot in the mouth for dental treatment. It may help make the experience less scary and more comfortable for kids.
Jizan, Jazan RegionAges 7–9 - NCT06982027Enrolling by invitation
Nerve block study for children having surgery
This trial tests a nerve block (an injection to numb a specific area) combined with general anesthesia during surgery. It may help children recover with less pain and fewer side effects from strong pain medicines.
Columbus, OhioAges birth–21 years - NCT06465992Enrolling by invitationPhase 4
Liposomal bupivacaine with dexamethasone for foot surgery pain relief
This trial tests whether adding dexamethasone to liposomal bupivacaine in a nerve block provides better pain relief after foot or ankle surgery. If you're having foot or ankle surgery and are willing to answer a few surveys, you may be able to join.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06139666Enrolling by invitationPhase 4
Liposomal bupivacaine nerve block for rotator cuff surgery
This study tests whether a long-lasting numbing medicine called liposomal bupivacaine (Exparel) works better than standard pain relief for people having rotator cuff surgery. It aims to lessen pain after surgery so you may need fewer pain pills.
Camden, New JerseyAges 18 years+ - NCT03365908Enrolling by invitation
Pain Management After ACL Reconstruction Surgery
This study looks at ways to manage pain in adults who are getting surgery to repair a torn ACL (a knee ligament). It may help improve comfort and recovery after ACL reconstruction.
Sacramento, CaliforniaAges 18–45 - NCT06143813Recruiting
Precision treatment for lumbar nerve pain with targeted block
This trial tests if a targeted nerve root injection can improve outcomes for people with persistent leg pain from a compressed nerve in the lower back, with the goal of tailoring surgery more precisely.
Aarhus CAges 18 years+ - NCT06075004Recruiting
Hip pain relief study comparing two injection methods
This trial tests two ways to give pain medicine around the hip joint during surgery to see which provides better pain relief. It may help patients experience less pain after hip replacement.
Santiago, Santiago MetropolitanAges 18–80 - NCT06515691Recruiting
Nerve block for pain after weight loss surgery
This study tests a nerve block (an injection near the nerves) to see if it helps reduce pain after laparoscopic sleeve gastrectomy. The block is called a modified thoracoabdominal nerve plane block, and it may lead to better pain control and recovery.
Istanbul, BagcilarAges 18–65 - NCT07409896Recruiting
Comparing two numbing shots for painful lower first molars
This study compares two numbing methods for severe tooth pain (pulpitis) in a lower first molar. If you have a tooth that needs a root canal and the pain lingers after cold, this trial may help determine which anesthetic works better for you.
Rawalpindi, Punjab ProvinceAges 18–55 - NCT07696312Recruiting
Straight leg raise test accuracy for leg pain
This study checks how well the straight leg raise test can find the exact nerve causing your leg pain by comparing it with a targeted nerve block injection. It may help if you have leg pain from a pinched nerve in your lower back.
Istanbul, PENDİKAges 18–65 - NCT06565910RecruitingPhase 4
Pain relief after hip surgery: long-acting vs standard numbing medicine
This study tests if a long-acting numbing medicine (bupivacaine liposome) combined with a standard numbing medicine works better for pain control after hip fracture surgery. It compares two different combinations to see which provides more effective pain relief.
Wuhan, HubeiAges 18–60 - NCT06577233RecruitingPhase 4
Nerve block before robotic endometriosis surgery
This trial tests if a nerve block (injecting numbing medicine) before robotic surgery for endometriosis can help control pain after the procedure. It's for women aged 18-65 who are already planning this surgery.
Houston, TexasAges 18–65 - NCT06636578RecruitingPhase 4
Adding dexmedetomidine to pain block for heart surgery
This study tests adding a medicine called dexmedetomidine to a standard pain-blocking injection (ropivacaine) used during heart surgery. The goal is to see if it reduces pain and speeds recovery better than the injection alone.
Al FayyumAges 20–65 - NCT07327892Recruiting
Comparing pain relief methods for hip surgery in older adults
This study compares three different ways to manage pain after hip surgery in older adults. One group gets a nerve block behind the hip, another gets the block plus a numbing injection around the joint, and the third gets only the numbing injection. The goal is to find the best method to reduce pain and help you recover more comfortably.
PoznanAges 65–100 - NCT06406010RecruitingPhase 4
Nerve block for pain after hip surgery
This trial tests whether a specific nerve block can reduce pain after a hip socket surgery. The results could help improve recovery and reduce the need for strong painkillers.
CopenhagenAges 18 years+
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Common questions
- Are there clinical trials for nerve block?
- Yes. Clin2 currently lists 224 recruiting nerve block studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nerve block trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nerve block trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.