Clinical trials
Nerve Block clinical trials
Below are recruiting nerve block clinical trials, each written for real people, not researchers. We’re tracking 222 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06908538Recruiting
Cryo nerve block for pain after amputation
This study is testing a treatment called a cryo nerve block to reduce pain after amputation, including phantom limb pain. It will look at whether freezing the nerve during surgery helps people feel less pain and use less pain medicine.
Pittsfield, MassachusettsAges 18 years+ - NCT06569953RecruitingPhase 4
Numbing Medicine for Pain After Lung Surgery
This study tests whether a long-lasting numbing medicine (liposomal bupivacaine) injected near the spine can better control pain after lung surgery. It compares this to a standard numbing medicine, and aims to help patients recover with less pain after surgery.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06869967Recruiting
Pain Control After Ear Surgery (Mastoidectomy)
This study tests a pain-blocking injection to reduce pain after a specific type of ear surgery (mastoidectomy). It may help you feel less pain after your operation.
IstanbulAges 18 years+ - NCT06639503RecruitingPhase 1
Nerve block for leg fracture surgery recovery
This trial tests if a nerve block given during surgery for a broken tibia (shin bone) can reduce pain after the operation. It may help you need fewer painkillers and recover more comfortably.
Chicago, IllinoisAges 18 years+ - NCT06631976Recruiting
Non-surgical treatment for partial rotator cuff tear
This trial tests a conservative (non-surgical) approach for people with a small tear in the supraspinatus tendon (a rotator cuff muscle) that is causing shoulder pain and sleep problems. It aims to see if avoiding surgery can help improve symptoms and sleep quality.
Lodz, Łódź VoivodeshipAges 40–75 - NCT06529432RecruitingPhase 2
Study of a long-acting painkiller for lung surgery recovery
This trial tests a long-acting pain medication (bupivacaine liposome injection) to control pain after lung surgery done through a small cut. It may help you feel more comfortable and reduce the need for other pain medicines.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06452147Recruiting
Anesthesia types for preventing confusion after hip surgery in older adults
This study looks at different ways to give anesthesia during hip surgery to help older patients think and remember better afterward. It may help prevent confusion or memory problems that sometimes happen after surgery.
Dongyang, ZhejiangAges 65 years+ - NCT06229964Recruiting
Frozen shoulder treatment: injection and nerve block
This trial compares two treatments for frozen shoulder: a corticosteroid injection into the shoulder joint and a nerve block (injection near the shoulder nerve) to reduce pain and improve movement. It aims to find which approach works better for people with frozen shoulder.
BrusselsAges 18–99 - NCT06182059Recruiting
Pain after knee replacement study
This study looks at long-term pain after total knee replacement surgery. It may help understand why some people have persistent pain and find ways to prevent it.
Monza, Monza BrianzaAges 18–85 - NCT05642026RecruitingPhase 4
Continuous nerve block for pain from multiple broken ribs
This study tests a continuous nerve block—a numbing medicine delivered near the nerves—to reduce pain from rib fractures. It may help people with two or more broken ribs manage pain more effectively while recovering.
Lexington, KentuckyAges 18 years+ - NCT05501262Recruiting
Cryoablation vs steroid injection for Morton’s neuroma pain
This trial compares two ways to treat Morton’s neuroma pain: freezing treatment (cryoablation) versus steroid plus lidocaine injections. It may help people who didn’t improve after trying basic shoe inserts or padding, by seeing which approach works better for symptoms.
Portland, OregonAges 18–105 - NCT06016465RecruitingEarly Phase 1
Nerve block plus steroid to prevent migraine return in 72 hours
This trial tests whether adding a steroid pill (dexamethasone) to a nerve block can stop a migraine from coming back within three days. It's for people whose headache got much better after a nerve block.
El Paso, TexasAges 18–85 - NCT05734625RecruitingPhase 2
Nerve block injections for episodic migraine pain relief
This Phase 2 trial tests whether nerve block injections can reduce pain from episodic migraines. It may help some people who get frequent migraine attacks but are not also using certain migraine preventions or strong pain medicines.
Rochester, MinnesotaAges 18 years+ - NCT05335070RecruitingPhase 2
Study to reduce pain from wisdom tooth extractions
This Phase 2 study tests ways to reduce pain during and after wisdom (back) tooth extractions done with IV sedation. It may help you have a more comfortable experience by improving how pain is managed after the procedure.
Newark, New JerseyAges 18–64 - NCT03365908Enrolling by invitation
Pain Management After ACL Reconstruction Surgery
This study looks at ways to manage pain in adults who are getting surgery to repair a torn ACL (a knee ligament). It may help improve comfort and recovery after ACL reconstruction.
Sacramento, CaliforniaAges 18–45 - NCT06143813Recruiting
Precision treatment for lumbar nerve pain with targeted block
This trial tests if a targeted nerve root injection can improve outcomes for people with persistent leg pain from a compressed nerve in the lower back, with the goal of tailoring surgery more precisely.
Aarhus CAges 18 years+ - NCT06075004Recruiting
Hip pain relief study comparing two injection methods
This trial tests two ways to give pain medicine around the hip joint during surgery to see which provides better pain relief. It may help patients experience less pain after hip replacement.
Santiago, Santiago MetropolitanAges 18–80 - NCT06515691Recruiting
Nerve block for pain after weight loss surgery
This study tests a nerve block (an injection near the nerves) to see if it helps reduce pain after laparoscopic sleeve gastrectomy. The block is called a modified thoracoabdominal nerve plane block, and it may lead to better pain control and recovery.
Istanbul, BagcilarAges 18–65 - NCT06636578RecruitingPhase 4
Adding dexmedetomidine to pain block for heart surgery
This study tests adding a medicine called dexmedetomidine to a standard pain-blocking injection (ropivacaine) used during heart surgery. The goal is to see if it reduces pain and speeds recovery better than the injection alone.
Al FayyumAges 20–65 - NCT07696312Recruiting
Straight leg raise test accuracy for leg pain
This study checks how well the straight leg raise test can find the exact nerve causing your leg pain by comparing it with a targeted nerve block injection. It may help if you have leg pain from a pinched nerve in your lower back.
Istanbul, PENDİKAges 18–65 - NCT07409896Recruiting
Comparing two numbing shots for painful lower first molars
This study compares two numbing methods for severe tooth pain (pulpitis) in a lower first molar. If you have a tooth that needs a root canal and the pain lingers after cold, this trial may help determine which anesthetic works better for you.
Rawalpindi, Punjab ProvinceAges 18–55 - NCT06565910RecruitingPhase 4
Pain relief after hip surgery: long-acting vs standard numbing medicine
This study tests if a long-acting numbing medicine (bupivacaine liposome) combined with a standard numbing medicine works better for pain control after hip fracture surgery. It compares two different combinations to see which provides more effective pain relief.
Wuhan, HubeiAges 18–60 - NCT07327892Recruiting
Comparing pain relief methods for hip surgery in older adults
This study compares three different ways to manage pain after hip surgery in older adults. One group gets a nerve block behind the hip, another gets the block plus a numbing injection around the joint, and the third gets only the numbing injection. The goal is to find the best method to reduce pain and help you recover more comfortably.
PoznanAges 65–100 - NCT07213622Enrolling by invitation
Smart glasses for numbing nerve block during knee replacement
This study tests if using smart glasses (like high-tech glasses that show a video) can help doctors give a more accurate numbing injection (nerve block) to the saphenous nerve for knee replacement surgery. The goal is to improve pain control after surgery.
Cleveland, OhioAges 18 years+
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Common questions
- Are there clinical trials for nerve block?
- Yes. Clin2 currently lists 222 recruiting nerve block studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nerve block trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nerve block trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.