Clinical trials
Neuroplasticity clinical trials
Below are recruiting neuroplasticity clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04806568Recruiting
Cognitive training to help brain flexibility in multiple sclerosis
This study tests whether structured cognitive exercises can improve “neuroplasticity,” meaning how flexible and changeable the brain is. It includes people with multiple sclerosis and healthy volunteers, and uses tasks plus brain scans to see what changes over time.
Thessaloniki, Central MacedoniaAges 18–65 - NCT05471960Recruiting
Brain training study in people with REM sleep behavior disorder
This study looks at how the brain changes (“neuroplasticity”) in people diagnosed with isolated REM sleep behavior disorder (iRBD) using brain stimulation and other testing. Results may help researchers understand brain differences in iRBD and guide future treatments.
Minneapolis, MinnesotaAges 21–75 - NCT07663292Recruiting
Exercise program to improve walking after stroke
This study tests whether a 12-week exercise program can help people who have had a stroke walk better. It focuses on those with a slower walking speed and uses brain scans to see if exercise can trigger positive changes in the brain.
Atlanta, GeorgiaAges 18–80 - NCT06372054Recruiting
Predicting health risks for Italian Air Force members
This study aims to develop smart risk models using your body's data (like proteins and genes) along with personal exposure readings. It will help predict health risks for Italian Air Force personnel. You will wear a monitor and give samples, then be followed over time.
MilanAges 26–38 - NCT07438808Recruiting
How exercise affects brain flexibility in healthy adults
This study looks at how physical exercise might change the way the brain adapts and stays flexible in healthy younger and older adults. You may be able to join to help researchers understand how staying active keeps the brain sharp.
Loos, NordAges 20–80 - NCT07183033Enrolling by invitation
VR brain training for older adults with mild memory and health issues
This trial uses virtual reality exercises to see if they can help improve brain function in older adults who have some memory concerns and physical frailty. Researchers want to know if a fun, interactive VR program can strengthen connections in the brain and improve daily life.
Beijing, Beijing MunicipalityAges 60 years+ - NCT06601933RecruitingPhase 2
Computer thinking exercises for memory concerns in older adults
This study tests whether a computer-based thinking exercise program can improve memory and brain function in older adults with mild memory concerns. If you have age-related memory changes but not dementia, you may be able to join and get a free MRI scan.
Miami, FloridaAges 55–89 - NCT06404268RecruitingPhase 1/Phase 2
Helping stroke survivors regain ankle movement with exercise
This study tests whether gentle leg exercises can help people recovering from a recent stroke. The focus is on improving ankle movement and strength on the weak side.
Baltimore, MarylandAges 30–85 - NCT07243600Recruiting
Brain Training for Memory in Mild Cognitive Impairment
This study tests a computer-based brain-training program designed to improve memory and thinking skills in older adults with mild cognitive impairment (MCI). It aims to see if these exercises can help keep the brain healthy and slow down memory decline.
Montreal, QuebecAges 65 years+ - NCT07715591Recruiting
Relaxing breathing during awake cataract surgery
This study tests a special breathing and pain education program to help you stay calm and comfortable during cataract surgery while you are awake. It may reduce pain and anxiety without extra medicine.
Los Angeles, CaliforniaAges Any age - NCT06465290Recruiting
Brain recovery treatment for recent stroke with ankle stiffness
This trial tests a treatment to help your brain recover after a stroke. It focuses on improving ankle movement and leg strength using exercises that promote brain rewiring.
Baltimore, MarylandAges 30–85 - NCT03610763Recruiting
Training brain recovery after arm nerve repair
This study tests a way to help your brain and nerves work better after an arm/hand nerve repair that is already in the long-term (chronic) recovery stage. It may help improve hand and arm function by targeting “neuroplasticity,” meaning the brain’s ability to adapt after injury.
Louisville, KentuckyAges 18 years+ - NCT04604444Recruiting
Rehab program to improve speech brain plasticity after stroke
This study looks at how intensive therapy can change the brain’s ability to relearn speech after a stroke that caused language or speech planning problems. You may be a good candidate if your stroke-related aphasia or apraxia was diagnosed by a speech specialist about 7 months ago.
UppsalaAges 18–75 - NCT04629352Recruiting
tDCS brain-stimulation for hearing voices in schizophrenia
This study tests whether a non-invasive brain-stimulation treatment (tDCS) can improve response to care in people who experience clinically significant hearing voices. It may help by changing brain activity, aiming to reduce or improve auditory hallucinations.
Bengaluru, KarnatakaAges 18–45 - NCT04759326Recruiting
Hippotherapy after stroke to improve movement and function
This trial studies whether therapy using a horse (hippotherapy) can help adults who still have stroke-related physical difficulties more than 3 months after their stroke. It aims to improve daily function and movement when standard recovery has not been enough.
La CanourgueAges 18 years+ - NCT05242393Recruiting
How daily body rhythms relate to recovery after stroke
This observational study looks at how your body’s daily rhythms may affect brain recovery after an ischemic stroke. It may help researchers understand what timing-related factors influence “neuroplasticity,” meaning the brain’s ability to adjust and heal.
Saint PetersburgAges 18–80 - NCT05247125RecruitingPhase 4
Testing light or melatonin to help brain recovery after stroke
This study looks at whether changing your sleep timing using light therapy or melatonin can improve “brain rewiring” after an ischemic stroke. It mainly focuses on people who arrive very soon after stroke symptoms and who also meet specific safety and sleep/medication requirements.
Saint PetersburgAges 18–80 - NCT05315726Recruiting
Vibration therapy to reduce stiffness after stroke
This trial studies whether regular muscle vibration can reduce post-stroke muscle stiffness and improve how the brain and nerves adapt. If you’re in the right stage after stroke, it may help improve arm and hand movement.
Chalon-sur-SaôneAges 18 years+ - NCT05495984Recruiting
Brain change study for mothers in opioid treatment
This study looks at whether supportive interventions can affect brain “plasticity,” or how the brain adapts, in mothers who are in treatment for opioid use disorder. If you qualify, you may be asked to take part in assessments and follow-up so researchers can better understand recovery during early motherhood.
New Haven, ConnecticutAges 21–45 - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
New York, New YorkAges 55 years+ - NCT05956327Recruiting
Study physical training to change brain signals in schizophrenia
This trial studies whether structured physical training can change brain “signal wiring” in people with schizophrenia. Researchers will also look at related molecular changes to understand why exercise might improve symptoms.
Munich, BavariaAges 18–65 - NCT06125054RecruitingPhase 2
Ketamine and brain training for cocaine addiction
This trial tests whether a combination of ketamine (a medicine that may help the brain change) and neurofeedback training (a brain-exercise technique) can help people with cocaine addiction. The goal is to see if these treatments can improve brain flexibility and reduce cravings.
Zurich, Canton of ZurichAges 18–55 - NCT06213012Recruiting
Spinal stimulation and rehabilitation for walking recovery after spinal cord injury
This study tests whether non-invasive electrical stimulation of the spinal cord, combined with physical therapy, can improve your ability to stand and walk after a spinal cord injury. It explores how your brain and spinal cord can adapt and rebuild connections to help you move better.
Houston, TexasAges 22–75 - NCT06225245Recruiting
Spinal cord stimulation for arm recovery
This study tests whether a device placed on the spinal cord (called an epidural stimulator) can help improve arm and hand function in people with chronic spinal cord injuries. The goal is to boost nerve activity and make rehabilitation more effective.
Houston, TexasAges 22–65
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Common questions
- Are there clinical trials for neuroplasticity?
- Yes. Clin2 currently lists 37 recruiting neuroplasticity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuroplasticity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuroplasticity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.