Clinical trials
Obesity and Type 2 Diabetes clinical trials
Below are recruiting obesity and type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 273 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05179954Recruiting
Blood fat testing study in adults with and without type 1 diabetes
This study measures how “blood fats” move in the body after fasting and controlled eating, comparing people with type 1 diabetes to those without diabetes. It may help researchers understand diabetes-related differences in lipid (fat) handling and improve future treatments.
Columbia, MissouriAges 18–45 - NCT06374368Recruiting
Small bowel diversion surgery for obesity
This trial tests a surgery called small bowel diversion to help people with obesity lose weight. It may also improve blood sugar control for those with type 2 diabetes.
OstravaAges 18–65 - NCT06770621Recruiting
Glucagon response study in new type 1 diabetes
This study looks at how the body makes glucagon (a hormone that raises blood sugar) in children and teens with new type 1 diabetes. It aims to understand why some people may have dangerous low blood sugars, so doctors can better prevent them in the future.
Brussels, Woluwe-saint-lambertAges 2–30 - NCT07270172Recruiting
Micronutrient study for type 1 diabetes complications
This study tests how a specific drug affects heart and kidney health in people with type 1 diabetes who already have some complications like kidney disease, heart problems, or obesity. It aims to find new ways to prevent further damage.
Aarhus NAges 40 years+ - NCT01999361Recruiting
Prevent new immune reaction after islet transplant failure
This study looks at ways to prevent the body from developing a new harmful immune reaction after an islet transplant no longer works. It may help people who have already lost a transplanted islet graft from getting harder-to-treat immune responses later.
Miami, FloridaAges 18–70 - NCT05498116RecruitingPhase 4
Montelukast to improve kidney and blood vessel function in type 1 diabetes
This trial tests whether montelukast, a medicine commonly used for allergies, can improve kidney health and blood vessel function in adults with long-term type 1 diabetes. You may join a treatment group and have kidney and circulation measurements taken over the study period.
Aurora, ColoradoAges 18–80 - NCT06581120Enrolling by invitation
Stomach ultrasound study for diabetes and obesity
This study uses ultrasound to see how GLP-1 RA medications (like Ozempic) affect the stomach in people with type 2 diabetes and obesity. It may help doctors better understand how these medicines work.
Cincinnati, OhioAges 10–25 - NCT06724406Recruiting
Family-centered weight loss for Black adults
This trial tests a weight loss program for Black adults and a family partner. You and a family member work together to lose weight with support from a smartphone or computer.
Chapel Hill, North CarolinaAges 18–75 - NCT03407833Enrolling by invitation
Study changes in the body after weight, gut, or liver treatment
This study looks at how the body’s insulin-sensitivity (how well your body uses sugar/insulin) and organ function change after certain medical procedures. It may help researchers understand why some people improve after surgery or liver transplant and guide future care.
Nashville, TennesseeAges 18 years+ - NCT06703788RecruitingPhase 1/Phase 2
Traditional Chinese Medicine Day Care for Metabolic Syndrome
This trial tests a day care program that combines traditional Chinese medicine with regular care for people with metabolic syndrome. It aims to see if this approach helps improve your health better than standard care alone.
TaoyuanAges 20–75 - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07351110Recruiting
Cervical cancer prevention for women with obesity or diabetes
This trial tests a program to help women with obesity or type 2 diabetes get cervical cancer screenings. It uses text messages or emails to remind and support you in getting screened.
Gainesville, FloridaAges 25 years+ - NCT05561595Recruiting
Reducing health-related stigma through group support
This trial tests a virtual group program to help people cope with health-related stigma from conditions like obesity, cancer, HIV, diabetes, skin disease, or chronic pain. It aims to reduce internalized stigma and improve well-being.
Gainesville, FloridaAges 18 years+ - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT07403604RecruitingPhase 1
Lowering Insulin to Reduce Fat Buildup in the Liver
This study tests if lowering insulin levels can reduce fat buildup in the liver for people with a fatty liver condition called MASLD. It's looking for adults who are overweight and have early signs of insulin resistance but not diabetes.
New York, New YorkAges 18–65 - NCT06802861Recruiting
Aspirin metabolism in pregnant women at risk of pre-eclampsia
This study looks at how pregnant women at risk of pre-eclampsia process aspirin and how it affects their metabolism. Researchers will use blood and urine tests, along with body measurements and surveys, to learn more about how aspirin can help prevent pre-eclampsia.
Knoxville, TennesseeAges 18–45 - NCT06446531RecruitingPhase 1
Preventing diabetes progression in Hispanic adults
This trial tests if a medication can prevent or slow the progression from prediabetes to type 2 diabetes and reduce heart risk. It is for Hispanic adults who are overweight and have prediabetes.
San Antonio, TexasAges 18 years+ - NCT06885736Recruiting
Preserving muscle with exercise and protein on weight loss drugs
This trial tests whether adding resistance exercise and extra protein can help you keep your muscle while taking weight loss medications like semaglutide or tirzepatide. It is for people with a BMI of 27 or higher who are not already exercising regularly.
Kuwait CityAges 18 years+ - NCT06364644Recruiting
Reducing heart failure risk in low-income adults with diabetes
This study looks at how low income and diabetes together raise the risk of heart failure. It offers a program to help you manage your health and reduce that risk.
Baltimore, MarylandAges 30–70 - NCT07171723RecruitingPhase 1/Phase 2
Study of LEAP2 on eating control during semaglutide treatment
This study looks at how a natural hormone called LEAP2 affects your appetite and eating behavior while you are taking semaglutide (a weight loss medicine). The results might help doctors understand how to make weight loss treatments even better.
HellerupAges 18–65 - NCT04643262Enrolling by invitation
Looking back at bariatric surgery outcomes in obesity
This study looks back at people who had sleeve gastrectomy (a weight-loss operation) and compares results and complications. It may be a fit if you match the study’s age, weight, and health history, though it’s a “retrospective” review, so it mainly uses past records.
Ages 18–68 - NCT04735835Recruiting
Personalized diet testing using ZOE app and blood samples
This trial studies how different food compositions affect your body, using the ZOE testing program plus meals you eat and blood samples you collect. It may help you learn more about what foods work best for you, especially if you have a long-term health condition.
Needham, MassachusettsAges 18 years+ - NCT07065643Recruiting
Calorie restriction study for healthy overweight adults
This study looks at how sex hormones affect the benefits of a low-calorie diet in men and women of different ages. If you are a healthy overweight adult, the study may help understand how hormones and age influence weight loss results.
AberdeenAges 18–65
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Common questions
- Are there clinical trials for obesity and type 2 diabetes?
- Yes. Clin2 currently lists 273 recruiting obesity and type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity and type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity and type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.