Clinical trials
Obesity and Type 2 Diabetes clinical trials
Below are recruiting obesity and type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 273 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07423065Recruiting
Continuous glucose monitor for prediabetes and weight loss
This study tests whether wearing a continuous glucose monitor (a small sensor on your skin that tracks your blood sugar) can help people with prediabetes and obesity better control their blood sugar and lose weight. You will be asked to wear the device for several days to see how your glucose levels change throughout the day.
IzolaAges 18–70 - NCT06762314RecruitingPhase 2
Empagliflozin or semaglutide for overweight people with type 1 diabetes
This study tests two different medicines (empagliflozin or semaglutide) added to your usual insulin to see if they help with blood sugar control and weight loss in people with type 1 diabetes who are overweight or have obesity. It may be a good fit if your diabetes is not well controlled with insulin injections alone.
TantaAges 18–65 - NCT06886126RecruitingPhase 2
Testing HDM1005 injection for weight loss in adults with obesity
This study tests an experimental injection called HDM1005 for adults with obesity who do not have diabetes. The goal is to see if it helps with weight loss when combined with diet and exercise.
NanjingAges 18–65 - NCT07513168RecruitingPhase 4
Low-dose semaglutide for weight loss in obese adults
This study tests whether a low dose of semaglutide (a once-weekly injection) can help obese adults without diabetes lose weight. Semaglutide works by reducing appetite and helping your body use food differently.
Hyderābād, SindhAges 18 years+ - NCT05674799Recruiting
Program to lower future obesity and diabetes risks
This trial tests a lifestyle and coaching program (NDPP-NextGen) to help reduce the chances of obesity and diabetes risk passing to the next generation. It’s for people planning a pregnancy soon and who may be at higher risk due to body weight.
Winston-Salem, North CarolinaAges 18–39 - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Glendale, ArizonaAges 18 years+ - NCT05228860Recruiting
Nutrition support program for adults with type 2 diabetes
This trial tests whether improving access to healthy food can help adults with type 2 diabetes—especially people dealing with food insecurity. It also includes a family member who helps support healthy eating at home.
Concord, CaliforniaAges 18 years+ - NCT05840497Recruiting
Exercise program to help lower gestational diabetes risk
This trial tests whether a strength and resistance exercise program during pregnancy can help reduce gestational diabetes in people who are overweight or obese. It may help by improving how your body handles sugar during pregnancy.
Pamplona, NavarreAges 18 years+ - NCT07247084RecruitingPhase 4
Tirzepatide for weight loss in adults with obesity
This trial tests if tirzepatide is more effective than standard obesity treatments for adults who have a BMI between 30 and 35 and one weight-related health condition, but do not have diabetes. The goal is to help you lose weight.
AltrinchamAges 18 years+ - NCT06396416RecruitingPhase 4
Obesity management after kidney transplant
This study tests whether a weight loss medication (semaglutide) can help manage obesity in people who have had a kidney transplant or are at high risk. It aims to improve health outcomes and prevent further kidney decline.
London, OntarioAges 18 years+ - NCT06856291Recruiting
Semaglutide for obesity with different insulin resistance levels
This study tests whether semaglutide (a weight-loss medication) works differently in people with varying degrees of insulin resistance (how well your body uses sugar). If you are obese without diabetes, you may be able to join.
Aarau, Canton of AargauAges 18–60 - NCT06439277RecruitingPhase 3
Tirzepatide for teens with obesity and related health problems
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Los Angeles, CaliforniaAges 12–17 - NCT07101939RecruitingPhase 2
Studying a medicine to preserve muscle during weight loss
This trial tests a new medicine, (S)-pindolol benzoate, given along with semaglutide (Ozempic/Wegovy). The goal is to see if it helps people lose mostly fat instead of muscle while on a weight loss program.
BelgradeAges 18–75 - NCT07284875RecruitingPhase 3
Ribupatide for weight loss in adults without diabetes
This trial tests a new medication, Ribupatide, to see if it helps people with obesity or overweight who also have weight-related health problems. You cannot have diabetes to join.
Anniston, AlabamaAges 18 years+ - NCT04634591Recruiting
Weight-loss surgery study for people with severe obesity
This trial studies bariatric (weight-loss) surgery and how well it helps people reach and keep a healthier weight. You may qualify if you have severe obesity and have not been able to maintain weight loss with other attempts, and if you can safely follow the study plan.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT06192251Recruiting
Lifestyle medicine program for chronic conditions
This trial tests a complete lifestyle medicine program to help people with conditions like prediabetes, diabetes, high blood pressure, heart disease, high cholesterol, or being overweight. The program aims to improve your overall health through diet, exercise, and other lifestyle changes.
Parry Sound, OntarioAges 18 years+ - NCT06571487Recruiting
Growth hormone resistance in beta cells after pregnancy
This study looks at how the body's insulin-making cells (beta cells) might become resistant to growth hormone after a full-term pregnancy. It compares women who had gestational diabetes to those who didn't, to learn more about diabetes risk. You may join if you had a healthy single-baby pregnancy in the last 5 years and never had type 1 or type 2 diabetes.
Columbia, MissouriAges 18–45 - NCT07070765Recruiting
Study on dapagliflozin to protect the heart during breast cancer chemo
This trial tests if a heart-protecting drug called dapagliflozin can help prevent heart damage in breast cancer patients receiving a type of chemotherapy called anthracycline. It may be an option if you have low to medium heart risk factors.
Aberdeen, AberdeenshireAges 18–70 - NCT07599072Recruiting
Blood Sugar Monitoring Study for Prediabetes
This study tracks how blood sugar levels change in people with prediabetes (higher-than-normal blood sugar but not yet diabetes). Researchers will use a small sensor to monitor your blood sugar and help understand what affects it, which could help prevent or delay type 2 diabetes.
KyivAges 18 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT07317310Recruiting
Joint health and weight loss study for knee osteoarthritis patients
This trial tests a joint health program for people with knee osteoarthritis and a BMI of 27 or higher. The goal is to see if it can improve knee pain and help with weight management.
Taipei, TaiwanAges 18–75 - NCT03528226Recruiting
Exercise program to improve blood vessel function in type 1 diabetes
This trial studies whether an exercise training program can improve how well your blood vessels work in people with type 1 diabetes. It may help assess benefits beyond blood sugar control.
LilleAges 18–50 - NCT07702461Recruiting
Resistance training survey for people on weight loss meds
This trial is an online survey to understand how people taking GLP-1 medications (like Ozempic or Wegovy) are doing with resistance training. If you're an adult on a stable dose of a GLP-1 med for weight or diabetes, your input can help shape better exercise advice.
Columbus, OhioAges 18 years+ - NCT04101669Recruiting
Diabetes device trial to improve blood sugar and weight
This study tests the RESET System to help people with type 2 diabetes lower their average blood sugar (HbA1c) despite current medication. It may also affect weight and safety outcomes by changing how food moves through the gut.
Washington D.C., District of ColumbiaAges 22–65
Hear when a new Obesity and Type 2 Diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for obesity and type 2 diabetes?
- Yes. Clin2 currently lists 273 recruiting obesity and type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity and type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity and type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.