Clinical trials
Obesity and Type 2 Diabetes clinical trials
Below are recruiting obesity and type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 274 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07539415RecruitingPhase 1
Safety and effectiveness study of new injection in healthy adults
This study tests a new experimental injection in healthy volunteers to see if it's safe and how well the body absorbs it. Researchers will compare it with other similar treatments to understand how it works.
SeoulAges 19–64 - NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70 - NCT07667504Recruiting
Dietary approaches for weight management in type 1 diabetes
This study tests two different diet approaches to help people with type 1 diabetes who are overweight or obese manage their weight. It aims to find out which eating plan works better for blood sugar control and weight loss.
Málaga, MálagaAges 18–65 - NCT03022682Recruiting
Study of inflammation and metabolism across diabetes and weight
This is an observational study that follows generally healthy adults to understand how inflammation, diabetes (type 2), and weight/metabolic health relate to each other. It may help researchers figure out why different groups (including different ethnic backgrounds) have different health risks.
San Francisco, CaliforniaAges 18–75 - NCT03087032RecruitingPhase 4
Liraglutide injections vs insulin for uncontrolled type 2 diabetes
This trial compares two treatment approaches—liraglutide injections versus a specific insulin (glargine) injection—plus meal-time insulin dosing (“bolus”) in adults with overweight/obesity and type 2 diabetes that isn’t well controlled. The goal is to see which option works better and is safer for improving blood sugar.
Xiamen, FujianAges 18–75 - NCT03132129Recruiting
Heart imaging study in adults with type 2 diabetes
This study looks for early, “silent” changes in heart function in adults with type 2 diabetes, even if you feel okay. It uses heart scans and looks for factors that may help explain why these changes happen.
LeicesterAges 50–75 - NCT03455868Recruiting
Bone health check after bariatric surgery in people with diabetes
This study looks at how bariatric (weight-loss) surgery affects bone health in adults with type 2 diabetes. It may help doctors understand who needs extra bone protection after surgery.
Montreal, QuebecAges 18–60 - NCT03569735Recruiting
Elderly health survey in Nanshan, Shenzhen
This study follows people age 65 and older in Nanshan to learn about health over time using surveys and health samples. It may help researchers understand what supports healthy aging in the community.
Shenzhen, GuangdongAges 65 years+ - NCT03821636Recruiting
Compare gastric bypass limb lengths for type 2 diabetes remission
This study looks at whether a gastric bypass surgery with a longer intestine segment or a longer bile drainage segment leads to better type 2 diabetes remission in people with severe obesity. It may help doctors choose the most effective surgical approach and follow-up plan for diabetes improvement.
AmiensAges 18–60 - NCT03842475Recruiting
Who may benefit from weight-loss surgery for diabetes?
This study looks at which people with type 2 diabetes (or prediabetes) are most likely to benefit from bariatric surgery. It compares people who are planning surgery with healthy volunteers to better understand how body changes relate to blood sugar.
London, Greater LondonAges 18–80 - NCT04024631Recruiting
Study genes and diabetes risk using body measurements
This study looks at how genetic risk relates to developing type 2 diabetes, using information from a biobank and body measurements like weight. It may help researchers better identify who is at higher risk before diabetes starts.
Philadelphia, PennsylvaniaAges 10–70 - NCT04187443RecruitingPhase 1
Drug MS-553 for diabetic eye swelling with reduced vision
This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.
Changsha, HunanAges 18 years+ - NCT04326192Recruiting
Spinal cord stimulation to reduce stubborn back and leg pain
This trial tests whether spinal cord stimulation (a treatment where a device sends mild signals to the spinal cord) can improve persistent nerve-type back and leg pain. It is mainly for adults who are already planning to try spinal cord stimulation but have not tried it before.
Portland, OregonAges 21–70 - NCT04432025Recruiting
Medication after weight-loss surgery for type 2 diabetes
This trial looks at whether a specific diabetes medicine given after bariatric (weight-loss) surgery can improve blood sugar control in people with type 2 diabetes. You might be considered if you are eligible for this surgery and meet the weight criteria.
DublinAges 18 years+ - NCT04442334Recruiting
European registry for people with fatty liver
This registry collects health and lifestyle information from adults with suspected or confirmed fatty liver (NAFLD) to help researchers better understand the condition. You may be asked about diet, exercise, alcohol intake, and some liver-related tests.
AntwerpAges 18–100 - NCT04442451Recruiting
Study how fatigue happens in prediabetes and type 2 diabetes
This study looks at why people with prediabetes or type 2 diabetes may feel unusually tired during activities. You may be asked to do exercise testing and answer questions to help researchers understand the body changes behind fatigue.
Ann Arbor, MichiganAges 30–85 - NCT04670666RecruitingPhase 3
Study of Madalena for type 2 diabetes not controlled
This Phase 3 study tests Madalena to improve blood sugar control in adults with type 2 diabetes that hasn’t met targets despite diet, exercise, and diabetes medicines. You may join if your recent blood sugar tests and body size fall within specific ranges and you don’t have key medical exclusions.
Hortolândia, São PauloAges 18 years+ - NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT04940962Recruiting
Study of fat tissue in obesity and type 2 diabetes
This study looks at a specific receptor (CB1) in abdominal fat tissue to understand how it affects fat-related chemicals in the body. Your participation would involve giving consent and having a tissue sample taken during planned internal (visceral) surgery.
DijonAges 18–80 - NCT04943926Recruiting
Diet changes to help put type 2 diabetes into remission
This study tests whether specific dietary strategies can help people with type 2 diabetes reach remission (better blood sugar without ongoing high medication needs). You may be a good candidate if your diabetes is relatively recent, your weight is above a certain threshold, and your heart and other health conditions are stable.
Bergen, VestlandAges 24–70 - NCT05000996Recruiting
Gut microbiome study for people having metabolic surgery
This study looks at your gut bacteria (your “microbiome”) around the time of metabolic surgery. It may help researchers understand how surgery affects gut health and related conditions like diabetes, blood pressure, and cholesterol.
Nashville, TennesseeAges 21–65 - NCT05008276Recruiting
Study of puberty, diabetes, and kidney stress in teens
This trial studies how puberty and blood sugar changes affect the kidneys in people with type 1 diabetes. It may help researchers understand early kidney risk and identify who needs closer monitoring.
Aurora, ColoradoAges 8–14 - NCT05117424Recruiting
Study of metabolism and plaque changes in heart disease
This trial looks at how treating or managing conditions like diabetes, prediabetes, obesity, kidney disease, or high cholesterol affects artery plaque over time. It may help researchers find ways to slow plaque buildup and related heart risks.
ShanghaiAges 18–80
Hear when a new Obesity and Type 2 Diabetes trial opens
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Common questions
- Are there clinical trials for obesity and type 2 diabetes?
- Yes. Clin2 currently lists 274 recruiting obesity and type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity and type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity and type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.