Clinical trials
Obesity and Type 2 Diabetes clinical trials
Below are recruiting obesity and type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 274 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05269589Recruiting
Home heat therapy for people with type 2 diabetes
This trial tests whether using heat therapy at home can improve health in adults with type 2 diabetes. It may help people who already have stable diabetes treatment, but it is not for everyone, especially if certain heart, nerve, or vision problems are present.
Montreal, QuebecAges 45–75 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT05349955Recruiting
Primary care diabetes guideline program for older adults
This trial tests whether a diabetes treatment plan (based on published guidelines) delivered by primary care doctors in the community is safe and helpful for older adults. It focuses on people with type 2 diabetes who also have kidney problems and/or higher heart and blood-vessel risk.
Suzhou, JaingsuAges 65 years+ - NCT05404061Recruiting
Study for people who don’t lose weight after bariatric surgery
This study looks at people who have had bariatric surgery but still struggle to lose weight (or lose it poorly). It aims to better understand how to help “poor responders” and what might be interfering with weight-loss results.
LondonAges 18–70 - NCT05414409RecruitingPhase 2
Gut microbiome study in young people with type 1 diabetes
This Phase 2 study looks at the gut microbiome (the bacteria in your intestines) in youth with type 1 diabetes, and how metformin may work differently through the gut. It may help researchers understand mechanisms and future treatment options.
Indianapolis, IndianaAges 11–18 - NCT05498974Recruiting
Type 1 diabetes study for people with insulin dependence
This study is looking for people with type 1 diabetes to better understand the condition and how it may be managed. You might qualify if you were diagnosed by a specialist and are insulin-dependent under certain conditions.
Lanzhou, GansuAges Any age - NCT05516576Recruiting
Weight-loss procedure plus diabetes care for type 2 diabetes
This trial studies whether an endoscopic (camera-guided) stomach tightening/suturing procedure plus standard diabetes care can improve health in people with type 2 diabetes and mild-to-moderate obesity. It compares this procedure to standard care alone to see which approach works better and is safe.
La TroncheAges 18–65 - NCT05589155Recruiting
Using a phone app to improve blood sugar and weight
This study looks at whether a mobile phone app can help people with type 2 diabetes improve their health habits, including blood sugar monitoring and weight. You may be able to join if you already check your blood sugar daily and are able to use a smartphone.
San Diego, CaliforniaAges 18–64 - NCT05651724Recruiting
MASH screening study for people with diabetes or obesity
This study screens participants for MASH (a type of liver fat inflammation) using information about your health and risk factors. It may help you and your care team learn whether you could have MASH and need follow-up.
Brussels, Vlaams-brabantAges 18–75 - NCT05706155Recruiting
Switching some animal protein to plant protein for Type 2 diabetes
This study tests whether replacing part of your animal protein with plant-based protein can improve Type 2 diabetes control. It may help your blood sugar and weight management without changing everything about your diet.
Porto Alegre, Rio Grande do SulAges 18–65 - NCT05759637Recruiting
Tests treatments for diabetes, weight, and high cortisol levels
This trial studies people who have type 2 diabetes and excess body weight, looking at how high cortisol (a stress hormone) may be involved. If you qualify, you may get a study treatment designed to improve diabetes and weight-related health by targeting cortisol-related pathways.
MilanAges 18–75 - NCT05799222Recruiting
Nutrition program for obesity and diabetes risk
This trial tests a medically guided nutrition program to help improve weight and blood sugar in adults with obesity or early diabetes risk. It specifically targets people who meet income guidelines and don’t already use most diabetes or anti-obesity medicines.
Boston, MassachusettsAges 18–65 - NCT05801614Recruiting
Tested diet to help control glucose in early type 2 diabetes
This study tests whether carbohydrate or calorie restriction can help normalize blood sugar levels in people with relatively early type 2 diabetes. It may help those whose diabetes control is not yet fully under control but who do not have major recent heart problems.
StockholmAges 24–70 - NCT05822544RecruitingPhase 1
Study of a diabetes medicine in healthy and obese volunteers
This early study tests TLC-6740 (a diabetes-type medicine) in people who are healthy and in people with obesity, with or without diabetes. The goal is to see how the medicine works in the body and check short-term safety.
AucklandAges 18–70 - NCT05844644RecruitingPhase 2
Golo plan for weight and blood sugar in prediabetes
This trial tests whether the Golo for Life plan (with a release supplement) can improve blood sugar and help with weight in adults who have prediabetes or type 2 diabetes. If you join, you’ll follow the program and attend clinic visits while your health, diet, and weight are tracked.
LaSalle, OntarioAges 18–75 - NCT05881447Recruiting
Study kidney disease patterns in people in Tanzania
This study looks at how common chronic kidney disease is, how it develops over time, and what risk factors are linked to it. It may help improve how kidney disease is recognized and managed in your community.
Bagamoyo, Coast RegionAges 18–99 - NCT05908812Recruiting
Testing how blood sugar control links to a hormone in type 2 diabetes
This study looks at whether better blood sugar control changes levels of a hormone called irisin in people with type 2 diabetes and obesity, including those with or without age-related muscle loss (sarcopenia). Your results may help researchers understand the body’s response to diabetes and could guide future treatment ideas.
BariAges 60 years+ - NCT05958368Recruiting
Avocado study to improve blood sugar in type 2 diabetes
This study tests whether eating avocados can improve blood sugar control in adults with type 2 diabetes. You may have blood tests and will follow a specific eating plan while your diabetes care continues under your doctor.
Baton Rouge, LouisianaAges 18–65 - NCT05962372Recruiting
Culturally tailored diet program for adults in Puerto Rico
This study tests a diet program designed to fit Puerto Rico culture and daily life. It may help adults with weight or blood sugar or blood fat concerns improve their health through regular check-ins.
San JuanAges 30–65 - NCT05987410Recruiting
Nordic walking for weight and heart health after a cardiac event
This trial tests if a nordic walking program helps people with diabetes who are overweight or obese recover after a heart attack or heart procedure. If you had a heart event or stent/bypass in the last 3 months, this program could help you get stronger and manage your weight.
MilanAges 18 years+ - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT06065930Recruiting
Adaptive Mechanisms in Grown-Up Obesity (AMIGROS)
This study looks at how the body adapts in people with different body weights and insulin sensitivity. It compares lean adults and those with obesity, with or without insulin resistance, to understand metabolism better. Participation involves a few visits and some tests.
Gothenburg, Region Vastra GotalandAges 40–70
Hear when a new Obesity and Type 2 Diabetes trial opens
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Common questions
- Are there clinical trials for obesity and type 2 diabetes?
- Yes. Clin2 currently lists 274 recruiting obesity and type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity and type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity and type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.