Clinical trials
Obesity and Type 2 Diabetes clinical trials
Below are recruiting obesity and type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 274 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07660445Recruiting
Endoscopic stomach reshaping and duodenal procedure for obese type 2 diabetes
This trial tests a procedure that reshapes the stomach and treats the upper intestine to help control blood sugar and weight in people with obesity and type 2 diabetes. It may be an option if you have a moderate to high need for metabolic surgery.
ShatinAges 18–70 - NCT07658755Recruiting
LiverSeek: Finding advanced liver scarring in MASLD
This study uses routine blood tests to find people with advanced liver scarring caused by a condition called MASLD. If you are between 50 and 75, have certain metabolic risks, and get blood work from your primary care doctor at select centers, you may be eligible.
Madrid, MadridAges 50–75 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Birmingham, AlabamaAges 18–79 - NCT07638345Recruiting
AI-powered weight management for teens with diabetes or asthma
This study tests a smartphone app that uses artificial intelligence to help families manage weight and health for teenagers (ages 12–21) with Type 1 Diabetes or asthma. The app is designed to be personalized to each family's needs and may help improve overall health outcomes.
SevilleAges 18 years+ - NCT07641361Recruiting
Staying Hydrated to Feel Better on GLP-1 Medication
This study tests whether drinking more water helps reduce uncomfortable side effects (like nausea and vomiting) when you first start taking GLP-1 medications for weight loss or diabetes. You'll be asked to follow a hydration plan and report how you feel.
Buffalo, New YorkAges 18–60 - NCT07636395Recruiting
How obesity medication affects your eating habits
This study tracks how your eating behavior changes when you take obesity medication. Researchers want to understand what happens to your appetite and food choices before, during, and after treatment to help improve how these medications work.
DublinAges 16–80 - NCT07622628Recruiting
AI-Guided Microbiome Nutrition for Better Blood Sugar Control
This trial tests whether a personalized nutrition plan based on your gut bacteria (microbiome) can help improve blood sugar control in type 2 diabetes. Researchers will use artificial intelligence to match you with a diet tailored to your unique gut bacteria.
IzmirAges 18–65 - NCT07605572Recruiting
GLP-1 drugs and dry eye disease in type 2 diabetes
This study tests whether a diabetes and weight-loss medication called GLP-1 receptor agonists affects dry eye disease. Researchers want to see if this medication helps or worsens dry eyes in people with type 2 diabetes and obesity.
AthensAges 18 years+ - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT07602023Recruiting
Fat Response and Diabetes Risk Study
This study looks at how your body processes fat after eating and measures certain blood markers to understand who might develop diabetes or complications. You'll eat a high-fat meal and have blood drawn to help doctors identify early warning signs.
Ferrara, FerraraAges 50–70 - NCT07588438RecruitingPhase 4
Tirzepatide effectiveness and safety for diabetes and weight loss in Paraguay
This study tests how well and safely tirzepatide (a new injectable medication) works in real-world conditions for people with type 2 diabetes or obesity in Paraguay. The medication helps lower blood sugar and reduce weight.
AsunciónAges 18–70 - NCT07578584RecruitingPhase 1
Safety study of NNC0497-0040 in healthy and overweight adults
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
NeussAges 18–55 - NCT07575438RecruitingPhase 2
Fish oil types for reducing diabetes risk
This study tests whether different types of fish oil can improve blood sugar and cholesterol levels in people at high risk for type 2 diabetes. The goal is to see if one type of fish oil is better at reducing diabetes risk.
Montreal, QuebecAges 40–70 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Birmingham, AlabamaAges 18 years+ - NCT07558863RecruitingPhase 4
GLP-1 medication's effect on nerve damage in type 2 diabetes
This study tests whether a GLP-1 medication (a type of diabetes drug) can help protect nerves in the heart from damage caused by diabetes. If you have type 2 diabetes and are overweight, this trial might help researchers understand if this medication improves how your heart's nervous system works.
Nanjing, JiangsuAges 18–70 - NCT07539415RecruitingPhase 1
Safety and effectiveness study of new injection in healthy adults
This study tests a new experimental injection in healthy volunteers to see if it's safe and how well the body absorbs it. Researchers will compare it with other similar treatments to understand how it works.
SeoulAges 19–64 - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Birmingham, AlabamaAges 18 years+ - NCT07518407Recruiting
Nutrition Education and Diet Guidance While Using GLP-1 Medication
This study teaches adults on GLP-1 medication (like Ozempic or Wegovy) how to eat better and lose weight using a smartphone app. Researchers want to see if personalized nutrition advice helps you get better results from your medication.
Columbia, South CarolinaAges 18–65 - NCT01477957Recruiting
Bariatric surgery and changes in insulin and body energy use
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
Düsseldorf, North Rhine-WestphaliaAges 20–70 - NCT07495020Recruiting
Weight loss surgery study for type 2 diabetes
This study tests a new type of weight loss surgery for people with type 2 diabetes and a body mass index (BMI) between 25 and 35. The surgery uses a clip and a special stitch to help with weight loss and diabetes control.
AstanaAges 18–65 - NCT03087032RecruitingPhase 4
Liraglutide injections vs insulin for uncontrolled type 2 diabetes
This trial compares two treatment approaches—liraglutide injections versus a specific insulin (glargine) injection—plus meal-time insulin dosing (“bolus”) in adults with overweight/obesity and type 2 diabetes that isn’t well controlled. The goal is to see which option works better and is safer for improving blood sugar.
Xiamen, FujianAges 18–75 - NCT07481747RecruitingPhase 3
Weekly injection for weight loss in adults with obesity
This trial tests a once-weekly injection (tirzepatide) versus a placebo to help people who are obese or overweight with related health conditions lose weight. You may qualify if you have tried to lose weight through diet before, but have not been successful.
Shenzhen, GuangdongAges 18 years+ - NCT07478263Recruiting
Healthy eating trial for Latinas to prevent type 2 diabetes
This study tests a behavioral program designed to help Latinas with prediabetes improve their nutrition and eating patterns to prevent type 2 diabetes. It focuses on reducing cravings and building healthy habits.
La Jolla, CaliforniaAges 18–55
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Common questions
- Are there clinical trials for obesity and type 2 diabetes?
- Yes. Clin2 currently lists 274 recruiting obesity and type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity and type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity and type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.