Clinical trials · Boston, MA
Obesity clinical trials in Boston
We’re tracking 63 recruiting obesity studies with a site in or near Boston — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06511310Recruiting
Exercise, brain health, and weight maintenance after weight loss surgery
This study looks at how exercise affects brain activity and helps people keep weight off after they have regained some weight following bariatric surgery. You may join if you had weight loss surgery, lost weight, and then regained more than 10% of that lost weight within the last 1 to 5 years.
Boston, MassachusettsAges 18–70 - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Boston, MassachusettsAges 18 years+ - NCT07467694Recruiting
Postnatal exercise to activate baby's brown fat
This trial tests if exercise after childbirth can activate your baby's brown fat, which helps with metabolism. It may benefit mothers and their healthy, full-term babies.
Boston, MassachusettsAges 18–45 - NCT05711758Recruiting
Endoscopic stomach muscle cut for weight loss
This trial tests whether an endoscopic procedure that cuts a stomach outlet muscle can help with weight loss and be safe. You would be screened to make sure you don’t have certain stomach, heart/lung, or pregnancy-related conditions that could make the procedure unsafe.
Boston, MassachusettsAges 18–70 - NCT04352244Recruiting
Study of brown fat activity in healthy adults
This study measures how “brown fat” works in the body using planned medical procedures. It looks at healthy adults to understand brown fat activity and what affects it.
Boston, MassachusettsAges 18–75 - NCT06200961Recruiting
Trans-nasal endoscopy for bariatric patients
This study tests a thinner, more comfortable endoscope that goes through the nose instead of the mouth for patients who need an upper GI exam. It may be a gentler option for weight-loss surgery patients.
Boston, MassachusettsAges 18–90 - NCT06432790Recruiting
In-person vs online healthy living and asthma program for kids
This study compares two programs for helping children with asthma who are overweight or obese — one that is held in person and another that is offered online. It tests whether learning about healthy habits and asthma management works better when done face-to-face or on a computer.
Boston, MassachusettsAges 4–17 - NCT06408961Recruiting
EVs in Obesity and Cardiometabolic Disease
This study looks at tiny particles released by cells (called extracellular vesicles, or EVs) in people with obesity and related heart health issues. Researchers want to see if these particles are different in people with obesity and diabetes, which could help find new ways to treat or prevent heart problems.
Boston, MassachusettsAges 18 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Boston, MassachusettsAges 18 years+ - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Boston, MassachusettsAges 6–17 - NCT06988462Recruiting
Bottarga supplement for metabolic health
This study tests a supplement called bottarga, made from fish eggs, to see if it improves cholesterol, blood sugar, or weight in people with metabolic problems like high cholesterol or prediabetes. It is a small pilot study for Massachusetts residents.
Sommerville, MassachusettsAges 18–60 - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Brighton, MassachusettsAges 18 years+ - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Quincy, MassachusettsAges 18 years+ - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Quincy, MassachusettsAges 18 years+ - NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
Waltham, MassachusettsAges 18 years+ - NCT07598981Enrolling by invitation
Obesity Medication Safety and Effectiveness Registry
This registry tracks how well obesity medications work and their safety in real-world use. You'll share your health information and experiences with your obesity medication over time to help doctors understand what works best for different people.
Waltham, MassachusettsAges 18 years+ - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
Waltham, MassachusettsAges 18 years+ - NCT04735835Recruiting
Personalized diet testing using ZOE app and blood samples
This trial studies how different food compositions affect your body, using the ZOE testing program plus meals you eat and blood samples you collect. It may help you learn more about what foods work best for you, especially if you have a long-term health condition.
Needham, MassachusettsAges 18 years+ - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Needham, MassachusettsAges 18–75 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Needham, MassachusettsAges 18–79 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Needham, MassachusettsAges 18–75 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Methuen, MassachusettsAges 18–79 - NCT07339423RecruitingPhase 3
A study of a new medicine for weight loss
This study tests a new medicine to see how well it helps people with excess body weight lose weight. It may be an option if you have tried to lose weight through dieting before but haven't had lasting success.
Cumberland, Rhode IslandAges 18 years+ - NCT07503210RecruitingPhase 3
Study of a new medicine to maintain weight loss
This study tests an investigational medicine to help people who have lost weight keep it off. It's for adults without diabetes who haven't used similar weight-loss drugs before.
Cumberland, Rhode IslandAges 18 years+
Hear when a new Obesity trial opens near Boston, MA
We’ll email you when one opens near Boston, MA — at most once a week, no account needed, unsubscribe anytime.
Obesity trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting obesity studies listed above.
- Brigham and Women's Hospital · 3 studies
- Knownwell · 3 studies
- Care Access · 2 studies
- Clinical Res Collaborative · 2 studies
- Joslin Diabetes Center · 2 studies
- Massachusetts General Hospital · 2 studies
- MedVadis Research Corporation · 2 studies
- ACCOMPLISH-1 Research Site
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting obesity studies in Massachusetts.
Common questions
- Are there obesity clinical trials near Boston?
- Yes. We're currently tracking 63 recruiting obesity studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.