Clinical trials · Boston, MA
Obesity clinical trials in Boston
We’re tracking 63 recruiting obesity studies with a site in or near Boston — including Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06138821Recruiting
Endoscopic sleeve gastroplasty for obesity and MASH
This study tests if a procedure called endoscopic sleeve gastroplasty helps people with obesity and a liver condition called MASH lose weight and improve their liver health. It might be an option if you have both obesity and MASH and haven't had weight-loss surgery before.
Boston, MassachusettsAges 18 years+ - NCT04551482RecruitingPhase 2
Oxytocin to help teens lose weight
This study tests whether the hormone oxytocin can help adolescents with obesity lose weight. You may be asked to stay on your usual diet and routines during the 18-week study to see how well the treatment works.
Boston, MassachusettsAges 10–18 - NCT07496463Enrolling by invitationPhase 2
Setmelanotide for weight loss in pseudohypoparathyroidism type 1a
This study tests an experimental medication called setmelanotide to see if it can help with weight loss in people who have pseudohypoparathyroidism type 1a (PHP1a), a rare genetic condition that often leads to obesity. The goal is to find a new treatment option for weight problems related to PHP1a.
Boston, MassachusettsAges Any age - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Boston, MassachusettsAges 6–17 - NCT01998750Recruiting
Study of genes in severe early childhood obesity
This study looks for genetic (inherited) reasons for severe obesity that starts in very early childhood. It may help doctors better understand the cause of your child’s weight gain and guide future treatment.
Boston, MassachusettsAges Up to 80 years - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Boston, MassachusettsAges 4 years+ - NCT07717658Recruiting
Family weight wellness program for teens and parents
This study tests a weight wellness program that uses food support and group medical visits for teens and their parents. It aims to help families adopt healthier habits together over 12 months.
Boston, MassachusettsAges 12–17 - NCT06408961Recruiting
EVs in Obesity and Cardiometabolic Disease
This study looks at tiny particles released by cells (called extracellular vesicles, or EVs) in people with obesity and related heart health issues. Researchers want to see if these particles are different in people with obesity and diabetes, which could help find new ways to treat or prevent heart problems.
Boston, MassachusettsAges 18 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Boston, MassachusettsAges 18 years+ - NCT07028814Enrolling by invitation
Risk-Informed Weight Care Plan for Children
This trial tests a personalized care plan for children with overweight or obesity. If your child qualifies, you'll work with their doctor on a plan to help manage their weight.
Boston, MassachusettsAges 2–12 - NCT06239116RecruitingPhase 1/Phase 2
RM-718 for obesity from hypothalamus injury or Prader-Willi syndrome
This study tests a new medicine called RM-718 for people with severe obesity linked to a specific brain pathway (MC4R). It may help if your obesity is due to a brain injury or tumor affecting the hypothalamus, or if you have Prader-Willi syndrome.
Boston, MassachusettsAges 12–65 - NCT05933499RecruitingPhase 2
Tirzepatide and bimagrumab for body fat and insulin sensitivity
This Phase 2 study tests two medicines to see how they change body fat, insulin sensitivity, and bone health in adults with obesity. It may help people who have tried lifestyle changes to lose weight but have not been able to, though diabetes and several health conditions must be ruled out first.
Boston, MassachusettsAges 18 years+ - NCT07776678Recruiting
Body fat and muscle measurement study
This study uses advanced body scans (like MRI and DXA) to better measure body fat and muscle. It may help improve how obesity is diagnosed and treated.
Boston, MassachusettsAges 18 years+ - NCT05464186Recruiting
Whole versus nonfat milk effects on kids’ body composition
This study compares whole milk vs nonfat milk to see how each affects body composition (such as fat and lean mass) in children. It may help families understand whether milk type makes a difference for healthy growth.
Boston, MassachusettsAges 9–12 - NCT04101669Recruiting
Diabetes device trial to improve blood sugar and weight
This study tests the RESET System to help people with type 2 diabetes lower their average blood sugar (HbA1c) despite current medication. It may also affect weight and safety outcomes by changing how food moves through the gut.
Boston, MassachusettsAges 22–65 - NCT06432790Recruiting
In-person vs online healthy living and asthma program for kids
This study compares two programs for helping children with asthma who are overweight or obese — one that is held in person and another that is offered online. It tests whether learning about healthy habits and asthma management works better when done face-to-face or on a computer.
Boston, MassachusettsAges 4–17 - NCT05725967Enrolling by invitation
Endoscopic and bariatric procedures for obesity
This study looks at people who are having obesity-related procedures, including options done with a scope (endoscopic) and revision after prior bariatric surgery. It may help doctors understand outcomes and improve care for people undergoing these treatments.
Boston, MassachusettsAges 18–80 - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Boston, MassachusettsAges 18 years+ - NCT07467694Recruiting
Postnatal exercise to activate baby's brown fat
This trial tests if exercise after childbirth can activate your baby's brown fat, which helps with metabolism. It may benefit mothers and their healthy, full-term babies.
Boston, MassachusettsAges 18–45 - NCT07156578Enrolling by invitationPhase 2
Long-term bivamelagon for hypothalamic obesity
This long-term study tests a new drug, bivamelagon, for people with hypothalamic obesity. It's for those who already completed a similar study and tolerated the drug well.
Boston, MassachusettsAges 12 years+ - NCT05711758Recruiting
Endoscopic stomach muscle cut for weight loss
This trial tests whether an endoscopic procedure that cuts a stomach outlet muscle can help with weight loss and be safe. You would be screened to make sure you don’t have certain stomach, heart/lung, or pregnancy-related conditions that could make the procedure unsafe.
Boston, MassachusettsAges 18–70 - NCT04352244Recruiting
Study of brown fat activity in healthy adults
This study measures how “brown fat” works in the body using planned medical procedures. It looks at healthy adults to understand brown fat activity and what affects it.
Boston, MassachusettsAges 18–75 - NCT06105164Recruiting
Brain's Fullness Circuit Study
This study uses brain imaging and mild magnetic stimulation to explore how a brain circuit helps you feel full after eating. It may help us understand eating behaviors and weight regulation.
Boston, MassachusettsAges 18–65 - NCT04907396Recruiting
Registry for adults trying to lose weight
This study is a registry that collects information from adults (18+) who are considering, currently working on, or have tried weight loss in the past. It may help researchers better understand weight-loss experiences and what strategies people use.
Boston, MassachusettsAges 18 years+
Hear when a new Obesity trial opens near Boston, MA
We’ll email you when one opens near Boston, MA — at most once a week, no account needed, unsubscribe anytime.
Obesity trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting obesity studies listed above.
- Brigham and Women's Hospital · 7 studies
- Massachusetts General Hospital · 6 studies
- Boston Children's Hospital · 4 studies
- Tufts Medical Center · 2 studies
- Tufts University · 2 studies
- Beth Israel Deaconess Medical Center
- Boston Medical Center
- Exponent Boston
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting obesity studies in Massachusetts.
Common questions
- Are there obesity clinical trials near Boston?
- Yes. We're currently tracking 63 recruiting obesity studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.