Clinical trials · Illinois
Obesity clinical trials in Illinois
We’re tracking 60 recruiting obesity studies with a site in Illinois — including Early Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT03135730Recruiting
ROHHAD patient registry for rapid-onset obesity
This study is a registry that collects information from people diagnosed with, or suspected to have, ROHHAD. It can help researchers better understand the condition over time and improve future care.
Chicago, IllinoisAges Any age - NCT04228978Recruiting
Lifestyle weight-loss program for people with PAD to stay mobile
This trial tests whether a healthy-lifestyle weight-loss program can help people with peripheral artery disease (PAD) lose weight and prevent worsening mobility. You may be eligible if you have PAD based on specific leg blood-flow test results and a higher body weight.
Chicago, IllinoisAges 18 years+ - NCT05125822Recruiting
Study of how bodies change weight in youth with obesity
This study looks at what helps or drives weight changes in children and teens with obesity. You may be asked about growth and body changes to better understand why weight changes happen and how to manage them.
Chicago, IllinoisAges 11–15 - NCT05326477Recruiting
Study factors that predict how well behavioral weight plans work
This study looks at which personal and health factors help or hurt how well behavioral obesity treatments work. It may help doctors better tailor weight-treatment plans for people with obesity.
Chicago, IllinoisAges 18 years+ - NCT07639021RecruitingPhase 2
Testing Different Dose Schedules of a New Weight Loss Medicine
This study tests a new injectable medication (NNC0662-0419) designed to help people with obesity lose weight. Researchers are comparing different ways of increasing the dose to find the safest and most effective approach.
Chicago, IllinoisAges 18 years+ - NCT06477120Recruiting
Time-restricted eating for pregnant women with severe obesity
This study tests whether eating only during a set window of time each day (time-restricted eating) can help manage weight gain during pregnancy for women with severe obesity. It might offer a safe, simple way to support a healthy pregnancy.
Chicago, IllinoisAges 18–44 - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Chicago, IllinoisAges 18–75 - NCT06734273RecruitingEarly Phase 1
Sleeve gastrectomy with tirzepatide for weight loss
This trial compares getting a sleeve gastrectomy alone versus getting it along with tirzepatide (a medicine that helps with weight loss and diabetes) to see if combining them leads to more weight loss. It may help people who are having their first sleeve gastrectomy.
Chicago, IllinoisAges 18–65 - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Chicago, IllinoisAges 4 years+ - NCT06864026RecruitingPhase 4
Adding tirzepatide to ixekizumab for psoriatic arthritis with weight concerns
This study tests adding tirzepatide (a once-weekly injection for weight and diabetes) to your current treatment with ixekizumab for psoriatic arthritis. It may help with both joint symptoms and weight.
Schaumburg, IllinoisAges 18 years+ - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
Hazel Crest, IllinoisAges 18–99 - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Skokie, IllinoisAges 18 years+ - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Chicago, IllinoisAges 18 years+ - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chicago, IllinoisAges 18–75 - NCT05082519RecruitingPhase 2
Calorie restriction and exercise to improve leukemia treatment in young patients
This study tests whether a special diet (calorie restriction) and increased physical activity can make chemotherapy work better for young people with B-ALL. Participants will follow a monitored diet and exercise plan during their first month of treatment.
Chicago, IllinoisAges 7–25 - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
Chicago, IllinoisAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Melrose Park, IllinoisAges 18 years+ - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Chicago, IllinoisAges 18–99 - NCT03527420Recruiting
Study of body fat, blood vessels, and DNA changes
This study looks at how having a high body mass index affects blood vessel function and changes in DNA. It may help researchers understand why weight-related health risks happen and how bariatric surgery could help.
Chicago, IllinoisAges 18–50 - NCT05199454Recruiting
Study how “fat-like” particles affect blood vessel function
This study looks at whether tiny fat-based particles (“adiposomes”) can affect how well your blood vessels work, especially in people with diabetes and higher body weight. You may be asked to do moderate exercise and other study procedures after passing safety checks.
Chicago, IllinoisAges 18–50 - NCT05687604Recruiting
Telehealth program to reduce cancer risk behaviors
This trial offers a scalable telehealth (phone/video) program to help people improve cancer risk habits like low physical activity, higher body weight, and smoking. It may help by giving structured coaching and support in the privacy of your home.
Chicago, IllinoisAges 18 years+ - NCT06239116RecruitingPhase 1/Phase 2
RM-718 for obesity from hypothalamus injury or Prader-Willi syndrome
This study tests a new medicine called RM-718 for people with severe obesity linked to a specific brain pathway (MC4R). It may help if your obesity is due to a brain injury or tumor affecting the hypothalamus, or if you have Prader-Willi syndrome.
Chicago, IllinoisAges 12–65 - NCT06292936Recruiting
Remi for weight regain after weight loss surgery
This study tests if the medication Remi can help people who have gained back at least 5% of their lowest weight after gastric bypass or sleeve gastrectomy. It is meant for those who are not currently using other weight loss drugs and are otherwise healthy enough to participate.
Chicago, IllinoisAges 18–70 - NCT07332741RecruitingPhase 2
Food as medicine for better blood pressure
This study tests a program that provides healthy food and support to help people with high blood pressure and a BMI of 30 or higher eat better and control their blood pressure. If you join, you'll get guidance on the DASH diet (a heart-healthy eating plan) and text messages to help you stay on track.
Chicago, IllinoisAges Any age
Obesity trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting obesity studies listed above.
- Ann & Robert H. Lurie Children's Hospital of Chicago · 5 studies
- Great Lakes Clinical Trials · 5 studies
- Northwestern University · 3 studies
- Rush University Medical Center · 3 studies
- University of Illinois · 3 studies
- Cedar Crosse Research Center · 2 studies
- Evanston Premier Healthcare Research · 2 studies
- NorthShore University HealthSystem · 2 studies
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity trials in other states
Common questions
- Are there obesity clinical trials in Illinois?
- Yes. We're currently tracking 60 recruiting obesity studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.