Clinical trials · Chicago, IL
Obesity clinical trials in Chicago
We’re tracking 59 recruiting obesity studies with a site in or near Chicago — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT05918575Recruiting
Breathing support after a breathing tube in very obese adults
This trial tests whether giving noninvasive breathing support (using a mask or similar device, without a new breathing tube) right after removing a breathing tube works better for severely obese adults. It mainly looks at people at higher risk of needing help breathing again after extubation.
Chicago, IllinoisAges 18 years+ - NCT07571109RecruitingPhase 3
Weight Loss Medicine for Sleep Apnea on CPAP
This study tests a new injectable medicine (NNC0487-0111) to help people lose weight and improve obstructive sleep apnea (a breathing condition during sleep). You must already be using a CPAP machine (positive airway pressure device) for your sleep apnea.
Chicago, IllinoisAges 18 years+ - NCT06292936Recruiting
Remi for weight regain after weight loss surgery
This study tests if the medication Remi can help people who have gained back at least 5% of their lowest weight after gastric bypass or sleeve gastrectomy. It is meant for those who are not currently using other weight loss drugs and are otherwise healthy enough to participate.
Chicago, IllinoisAges 18–70 - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Chicago, IllinoisAges 18 years+ - NCT07752979RecruitingPhase 2
New drug for weight loss in adults with obesity or overweight
This study tests an investigational drug called ABBV-295 to see if it helps adults with obesity or overweight who have weight-related health conditions lose weight. It may offer a new treatment option for managing weight and improving overall health.
Chicago, IllinoisAges 18–75 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Chicago, IllinoisAges 12–17 - NCT07566325Recruiting
Avocado and inflammation: can it improve your health?
This study tests whether eating avocado instead of refined carbohydrate foods (like white bread and sugary snacks) can reduce inflammation markers in your blood. If you have some signs of inflammation and extra weight around your middle, this might help researchers understand if avocado is a helpful dietary change.
Chicago, IllinoisAges 21–74 - NCT07685808RecruitingPhase 2
Testing a weight loss injection for people with overweight or obesity
This study tests an injectable medication called Olatorepatide to help people with overweight or obesity lose weight. It is only for people without diabetes who meet specific body mass index (BMI) requirements.
Chicago, IllinoisAges 18 years+ - NCT07794579RecruitingPhase 3
Study of orforglipron for people with overweight at risk of health problems
This trial tests a new medicine, orforglipron, to help people with overweight who are at risk of developing weight-related health issues. It aims to see if the medicine can help with weight management and reduce risks before more serious conditions develop.
Chicago, IllinoisAges 18 years+ - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Chicago, IllinoisAges 18 years+ - NCT05687604Recruiting
Telehealth program to reduce cancer risk behaviors
This trial offers a scalable telehealth (phone/video) program to help people improve cancer risk habits like low physical activity, higher body weight, and smoking. It may help by giving structured coaching and support in the privacy of your home.
Chicago, IllinoisAges 18 years+ - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Chicago, IllinoisAges 6–17 - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Chicago, IllinoisAges 18 years+ - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Chicago, IllinoisAges 18 years+ - NCT07288294Recruiting
Primary care strategies for weight management after stopping medication
This study looks at different ways to help you keep weight off after you stop taking a weight loss medication. You will work with your primary care team to learn healthy habits and get support without the drug.
Chicago, IllinoisAges 18 years+ - NCT03135730Recruiting
ROHHAD patient registry for rapid-onset obesity
This study is a registry that collects information from people diagnosed with, or suspected to have, ROHHAD. It can help researchers better understand the condition over time and improve future care.
Chicago, IllinoisAges Any age - NCT07720271RecruitingPhase 3
Zenagamtide weight loss study for adults
This study is testing a new tablet called Zenagamtide to help people with extra body weight lose weight. It's for adults who are not diabetic and haven't used similar weight loss drugs before.
Chicago, IllinoisAges 18 years+ - NCT07595549RecruitingPhase 3
Testing Berobenatide for Weight Loss in Overweight Adults
This study tests a new medicine called berobenatide to help people with overweight or obesity lose weight. The medicine may also help improve related health conditions like high blood pressure, high cholesterol, or type 2 diabetes.
Chicago, IllinoisAges 18 years+ - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Chicago, IllinoisAges 4 years+ - NCT03527420Recruiting
Study of body fat, blood vessels, and DNA changes
This study looks at how having a high body mass index affects blood vessel function and changes in DNA. It may help researchers understand why weight-related health risks happen and how bariatric surgery could help.
Chicago, IllinoisAges 18–50 - NCT07798557Recruiting
Lifestyle and diet support for weight and heart health
This study tests a program to help you improve your diet and lifestyle, which may reduce your risk for heart disease and help with weight loss. You will get support to make healthy changes over the next year.
Chicago, IllinoisAges 50–79 - NCT07789769Recruiting
Online weight loss program focusing on protein, fiber, and exercise
This study tests a 6-month online weight loss program that focuses on eating more protein and fiber and adding exercise—called the '30-30-30 Plan.' It's a chance to get support and guidance to help you reach your weight loss goals.
Chicago, IllinoisAges 18–69 - NCT07817875RecruitingPhase 3
Tirzepatide for weight loss in children aged 6 to under 12
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
Chicago, IllinoisAges 6–11 - NCT06636058Recruiting
Digital treatment for weight and mood in adults 50+
This study tests a digital program that helps with weight loss and depression at the same time. It is designed for Black, Hispanic, and other adults over 50 who carry extra weight and feel down.
Chicago, IllinoisAges 50–74
Hear when a new Obesity trial opens near Chicago, IL
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Obesity trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting obesity studies listed above.
- Ann & Robert H. Lurie Children's Hospital of Chicago · 4 studies
- Endeavor Health · 3 studies
- University of Illinois at Chicago · 3 studies
- Clinical Investigation Spec Gurnee · 2 studies
- Evanston Premier Hlthcr Res · 2 studies
- Great Lakes Clinical Trials · 2 studies
- Illinois Institute of Technology · 2 studies
- Rush University Medical Center · 2 studies
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting obesity studies in Illinois.
Common questions
- Are there obesity clinical trials near Chicago?
- Yes. We're currently tracking 59 recruiting obesity studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.