Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,434 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06859697Enrolling by invitation
Herbal medicine for obesity with spine or joint pain
This trial tests whether herbal medicine can safely help with pain and weight loss in people who have both obesity (BMI 25 or higher) and back or joint pain. It aims to see if the treatment works and is safe.
Seoul, Gangnam-GuAges 19–69 - NCT06855563Enrolling by invitation
Childhood obesity prevention study in schools
This study looks at ways to prevent childhood obesity in cities. Researchers will collect information from children ages 6 to 13 in participating schools to understand what helps kids stay healthy.
LoganAges 6–13 - NCT06852391RecruitingPhase 4
Weight loss program with or without semaglutide for teens with obesity
This trial studies how the body adapts to weight loss in teens with obesity. You will either get a behavioral lifestyle program alone or with a weight loss medication called semaglutide.
Hamilton, OntarioAges 12–17 - NCT06848478Recruiting
Exercise and diet program for teens with obesity
This study tests whether a structured exercise and healthy eating program can improve heart health in teenagers who have obesity. The program includes supervised workouts and fruit/vegetable smoothies, and it is designed to help teens build healthier habits.
Little Rock, ArkansasAges 12–17 - NCT06855251Recruiting
Sensing inner body states in obesity
This trial explores how people with obesity sense signals from their own body (like heartbeat or fullness). Understanding this connection could help develop better treatments.
Piancavallo, VCOAges 18–55 - NCT06842186RecruitingPhase 1/Phase 2
Study of WVE-007 for overweight or obesity
This trial tests an experimental drug called WVE-007 for people who are overweight or have obesity. It aims to help with weight loss and is looking at both a group without diabetes and a group with prediabetes or type 2 diabetes.
Baltimore, MarylandAges 18–60 - NCT06830343RecruitingPhase 1
Safety study of SYH9017 for overweight and obesity
This study tests a new medication called SYH9017 for people who are overweight or have obesity. It aims to see how safe the drug is, how well it is tolerated, and how the body processes it. Participants will receive either the drug or a placebo and be monitored closely.
Beijing, Beijing MunicipalityAges 18–60 - NCT06820099RecruitingPhase 2
A drug for heart failure with obesity
This trial tests an oral drug called HRS-7535 for people with a certain type of heart failure (where the heart pumps normally but doesn't relax properly) and who also have obesity. It aims to see if the drug can improve symptoms and daily function.
Beijing, Beijing MunicipalityAges 18–80 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+ - NCT06802081RecruitingPhase 2
Tirzepatide for weight loss in people with atrial fibrillation
This study tests whether tirzepatide, a medication that helps with weight loss and blood sugar control, can improve the heart rhythm condition atrial fibrillation. If you have AFib and are overweight or obese, this trial may be an option for you.
Cleveland, OhioAges 18–80 - NCT06800872Recruiting
Vibration therapy for weight loss in teens
This trial tests if whole body vibration can help teenagers with obesity burn more energy while staying in a hospital program. It may offer an extra tool to support weight management.
Oggebbio, VerbaniaAges 13–18 - NCT06802861Recruiting
Aspirin metabolism in pregnant women at risk of pre-eclampsia
This study looks at how pregnant women at risk of pre-eclampsia process aspirin and how it affects their metabolism. Researchers will use blood and urine tests, along with body measurements and surveys, to learn more about how aspirin can help prevent pre-eclampsia.
Knoxville, TennesseeAges 18–45 - NCT06786052RecruitingPhase 2
Study on after-meal energy in adults 50–70
This trial studies how a probiotic supplement affects energy use after meals in adults aged 50–70 who are overweight. You'll take either the probiotic or a placebo for several weeks.
Pierre-Bénite, Auvergne-Rhône-AlpesAges 50–70 - NCT06782139RecruitingPhase 4
Enavogliflozin for heart health in obesity and diabetes
This trial tests if Enavogliflozin, a medication for diabetes, can improve blood flow in the small vessels of the heart and overall heart function in people with obesity or diabetes. You may join if you have obesity or diabetes and have had a recent heart test.
SeoulAges 20–79 - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Birmingham, AlabamaAges 4 years+ - NCT06770049Recruiting
Personalized lifestyle program for weight loss in obesity
This study tests a lifestyle program tailored to your biology or behavior to help with weight loss. It is for adults with obesity who haven't had weight loss surgery or used certain weight loss medications recently.
Rochester, MinnesotaAges 18–65 - NCT06745063RecruitingPhase 2
Study of a diabetes drug to reduce artery stiffness in veterans with obesity
This trial tests whether an SGLT2 inhibitor (a type of diabetes medication) can help reduce stiffness in the arteries of veterans who have obesity. If you are a veteran aged 30-60 with a BMI of 30-45 and have stiffer arteries than expected for your age, this study might be an option.
Columbia, MissouriAges 30–60 - NCT06745570Recruiting
Sleep, decision-making, and eating habits study for teens with obesity
This study tests whether improving sleep and decision-making skills helps teenagers with obesity make healthier eating choices. It involves both teens and their parents or guardians.
Wilmington, DelawareAges 14–18 - NCT06727500Recruiting
Exercise training for kids with obesity
This trial tests whether two types of exercise training (high-intensity interval training or a mix of HIIT and jumping exercises) improve muscle and tendon health in children and teenagers with obesity. It looks at how results differ based on whether kids are before or after their growth spurt.
SantiagoAges 7–17 - NCT06736028Recruiting
Ketogenic diet for weight loss maintenance in obesity
This study tests whether a ketogenic diet helps people with obesity keep weight off by changing how your body burns energy and controls appetite. You will follow a low-carb, high-fat diet and be monitored for several months.
Birmingham, AlabamaAges 18–65 - NCT06721507RecruitingPhase 4
Tirzepatide after weight loss surgery
This study tests whether giving tirzepatide (a medicine that helps with weight and blood sugar) right after weight loss surgery can improve results. It is for people who are already scheduled for sleeve gastrectomy or gastric bypass at UK HealthCare.
Lexington, KentuckyAges 18 years+ - NCT05277714Recruiting
Neurofeedback for food addiction in people with obesity
This trial tests whether brain-training feedback using near-infrared sensors (a painless light-based brain measure) can reduce food addiction behaviors in people with obesity. If you qualify for obesity surgery and have food addiction signs, you may be offered this therapy and monitored during the study.
RennesAges 18–55 - NCT06620562RecruitingPhase 4
Testing a weight loss pill after sleeve gastrectomy surgery
This study tests whether adding a medication (naltrexone/bupropion) to sleeve gastrectomy surgery can improve weight loss. It may be a good fit if you are eligible for a first-time sleeve gastrectomy and meet certain health criteria.
Québec, QuebecAges 18–65
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,434 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.