Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,434 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06700538RecruitingPhase 1/Phase 2
Study of an experimental drug for obesity with or without type 2 diabetes
This study tests an experimental medication called ARO-INHBE in adults with obesity, including those who also have type 2 diabetes. The goal is to see if it helps with weight loss and is safe.
CamberwellAges 18–65 - NCT06687122Recruiting
Eggs, metabolism, and choline study
This trial studies how eating 3 eggs daily for 4 weeks affects your metabolism and choline levels. It may help if you have obesity and are looking for a simple dietary change to improve your health.
Québec, QuebecAges 30–65 - NCT06682481Recruiting
Pancreas-Liver Communication in Teens with Obesity
This study looks at how the pancreas and liver talk to each other in teens with obesity. It may help understand why some teens develop diabetes or fatty liver.
Geneva, Canton of GenevaAges 12–16 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Tucson, ArizonaAges 6–17 - NCT06669715Recruiting
Physical fitness and heart health in adults
This study looks at physical fitness and blood flow in a wide range of adults. It aims to understand how fitness affects heart health across different people.
LjubljanaAges 18 years+ - NCT06681246Recruiting
How gut bacteria affect weight regain after weight loss
This study looks at how the natural bacteria in your gut (the microbiome) might be linked to regaining weight after losing it. It tests whether a short course of antibiotics or a placebo (a sugar pill) affects this process. The goal is to find new ways to help people keep weight off long-term.
RehovotAges 18–65 - NCT06654323Recruiting
Behavioral program for childhood obesity
This study tests different levels of a behavioral program to help children with obesity lose weight and live healthier. Families will receive support and guidance over 12 months.
Baton Rouge, LouisianaAges 5–17 - NCT06645470Recruiting
Muscle and movement study for weight loss medications
This study looks at how anti-obesity medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) affect your muscles and movement. It may help researchers understand how to combine these drugs with exercise for better health.
Kansas City, KansasAges 18 years+ - NCT06649071Enrolling by invitation
Obesity classification and brain imaging study
This study looks at how obesity is classified and what brain imaging can show in people with obesity. It may help researchers understand different types of obesity and how they affect the brain.
Nanjing, JiangsuAges 20–65 - NCT06636773Recruiting
Aerobic vs Aerobic Plus Yoga for Weight Loss
This study compares two exercise programs — aerobic exercise alone versus aerobic exercise combined with yoga — to see which helps adults with overweight or obesity lose weight. You would need to follow a diet plan and attend regular exercise sessions at the University of Kansas Medical Center.
Kansas City, KansasAges 18 years+ - NCT06636058Recruiting
Digital treatment for weight and mood in adults 50+
This study tests a digital program that helps with weight loss and depression at the same time. It is designed for Black, Hispanic, and other adults over 50 who carry extra weight and feel down.
Chicago, IllinoisAges 50–74 - NCT06630663Recruiting
Wearable device and app for diet and exercise
This trial tests if a wearable device and a smartphone app can help you improve your diet and exercise habits. It is for people who are overweight and have related health conditions like high blood pressure or diabetes.
Taipei, TaipeiAges 20 years+ - NCT06626295Recruiting
Exercise snacks for teens with obesity
This study tests whether short, frequent 'exercise snacks' can help break up long periods of sitting and improve the physical fitness of teens with obesity. It's a simple, at-home approach that may fit into daily life.
Palavas-les-FlotsAges 11–18 - NCT06609200Recruiting
Electro-acupuncture for obesity with insulin resistance
This study tests whether electro-acupuncture (a type of acupuncture with mild electric pulses) can help people with obesity and insulin resistance improve their health. It may be an option if you're looking for a non-drug treatment for weight and blood sugar control.
SingaporeAges 21–65 - NCT06599918RecruitingPhase 2
Nicotinamide for liver scarring in fatty liver disease
This study tests whether nicotinamide (a form of vitamin B3) can help reduce liver scarring in people with nonalcoholic fatty liver disease. You may qualify if you have moderate to severe liver scarring and are between 18 and 85 years old.
BarcelonaAges 18–85 - NCT06583447Recruiting
Time-Restricted Eating for Kids with Severe Obesity
This study tests whether eating only during a set window of time each day can help children ages 8–17 with severe obesity lose weight in a healthy way. It is a safer alternative to extreme diets or surgery.
Suzhou, JiangsuAges 8–17 - NCT06572345Recruiting
Low energy diet for teens with obesity and type 2 diabetes
This trial tests whether a low-energy diet using meal replacements can help teenagers with type 2 diabetes improve their blood sugar control. It involves a period of following the diet, then weight management, and includes follow-up visits.
NottinghamAges 12–17 - NCT06578091Recruiting
Thinking skills in people with obesity
This study looks at how well the brain works in people with obesity. It compares those who score high on a cognitive test with those who score lower, to find differences in thinking skills.
Kütahya, CentralAges 18–65 - NCT06571474Recruiting
Fat Cell Function in Obesity and Metabolism Study
This study looks at how a type of immune cell (macrophage) in fat tissue processes lipids, and how that affects metabolism in people with different body weights. It may help us understand why some people with obesity develop diabetes and fatty liver while others do not.
Columbia, MissouriAges 18–70 - NCT06547775RecruitingPhase 1
Study of KN069 for people with obesity or overweight
This trial tests a new drug called KN069 to see if it can help people who are overweight or have obesity. It may offer a new treatment option for weight management.
Changsha, HunanAges 18–55 - NCT06538220Recruiting
A study on care for obese patients in a chronic disease unit
This study looks at how well a special care program works for people with obesity. It aims to improve health and quality of life through a dedicated chronic disease unit.
La Garde, VarAges 18 years+ - NCT06546696Recruiting
Obesity support program for children and families
This trial offers a 6-month program to help children ages 6–11 with obesity and their parents adopt healthier habits, including exercise and nutrition. It takes place at community centers in Middle Tennessee and provides online training.
Nashville, TennesseeAges 6–12 - NCT06537921Recruiting
Testing minocycline for depression with obesity
This trial tests whether adding the antibiotic minocycline to your current antidepressant helps people with both depression and obesity. It aims to see if reducing inflammation can improve mood.
LondonAges 18–65
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,434 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.