Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07526584Recruiting
Food Label Study in Indonesia
This study tests how different warning labels on packaged foods affect what people choose to buy in Indonesia. Researchers want to understand which label designs help people make healthier food choices.
Chapel Hill, North CarolinaAges 18 years+ - NCT07123779RecruitingPhase 1/Phase 2
Study of HS235 in obese patients with pulmonary hypertension and heart failure
This trial tests an investigational drug called HS235 in people who have both obesity (BMI 30-50) and a specific type of heart failure with preserved pumping function, along with high blood pressure in the lungs. The goal is to see if the drug can improve symptoms and quality of life.
Greenville, South CarolinaAges 18 years+ - NCT06921382Recruiting
Breastfeeding help to prevent childhood obesity
This study offers breastfeeding support to new mothers to help prevent childhood obesity. It is for Hispanic mothers who plan to breastfeed and are eligible for WIC.
Greensboro, North CarolinaAges 5 days+ - NCT07453563Recruiting
Comparing breathing tube devices in people with severe obesity
This trial compares two devices (Airway Scope and GlideScope) used to place a breathing tube during surgery in people with severe obesity. If you qualify, the study will help find which tool works best for patients like you.
Albuquerque, New MexicoAges 18 years+ - NCT07062094Recruiting
Safety and Effectiveness of the Orbera365 Balloon for Weight Loss
This study tests a temporary balloon placed in your stomach to help with weight loss. The balloon stays in place for about a year and is removed at the end of the study. It is for people with a BMI between 30 and 50 who are looking for a non-surgical option.
PragueAges 18 years+ - NCT07670884RecruitingPhase 3
Study of HRS9531 for weight loss in overweight or obese adults
This trial tests an oral medication, HRS9531, to help overweight or obese adults lose weight. It may be an option if you have been unable to lose enough weight through diet and exercise alone.
Zhengzhou, HenanAges 18–75 - NCT07746635Recruiting
Fecal transplant for obese women with polyendocrine metabolic ovarian syndrome
This study tests whether a fecal microbiota transplant (a transfer of healthy gut bacteria) can help women with polyendocrine metabolic ovarian syndrome who are also overweight or obese and planning a frozen embryo transfer. It aims to see if this treatment can improve hormone balance and possibly increase the chance of a successful pregnancy.
Shanghai, Shanghai MunicipalityAges 20–40 - NCT07238556Recruiting
Digital tool for doctors to prescribe exercise
This trial tests a digital tool that helps doctors create personalized exercise plans for patients with heart disease risk factors. It aims to help you become more active in a safe, supported way.
Farmington, ConnecticutAges 18–64 - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT07708064Recruiting
Preventing weight regain with a smartphone program
This study tests a smartphone-based program to help people who have lost weight keep it off or lose more. It uses personalized tips and check-ins to prevent giving up if you regain some weight.
Springfield, OregonAges 18–70 - NCT06830096Recruiting
Understanding a key cell channel in type 2 diabetes
This study looks at how a specific channel in your cells (called the KATP channel) affects blood sugar control in people with and without type 2 diabetes. It aims to understand why some people develop diabetes and how to better treat it.
St Louis, MissouriAges 18–65 - NCT07351110Recruiting
Cervical cancer prevention for women with obesity or diabetes
This trial tests a program to help women with obesity or type 2 diabetes get cervical cancer screenings. It uses text messages or emails to remind and support you in getting screened.
Gainesville, FloridaAges 25 years+ - NCT07275697RecruitingPhase 4
Weight loss drug and heart ablation study for AFib
This trial tests whether a weight loss medication (semaglutide) given before and after a first-time heart ablation procedure for atrial fibrillation can improve outcomes. It is for people who are overweight or obese and have certain related health conditions.
StockholmAges 18 years+ - NCT07282340RecruitingPhase 2
Phentermine for weight loss in teens
This study tests a medicine called phentermine to help teens ages 12 to 17 with obesity lose weight. It will check if the medicine is safe and works well for teenagers.
Baton Rouge, LouisianaAges 12–17 - NCT03481829Recruiting
Long-term study tracking health factors from pregnancy
This study follows pregnant mothers and their babies for years to understand how early life factors can affect health later. If you qualify, you and your child(ren) will be asked to stay in the research study for at least 3 years after delivery.
Phoenix, ArizonaAges 1 day–99 years - NCT06785064Recruiting
Helping with long-term weight loss maintenance support
This study tests an extended care program designed to help people keep weight off after losing it. You would join with a buddy (friend or family member) and attend online sessions via Zoom, along with a few in-person check-ins at the university.
Birmingham, AlabamaAges 18 years+ - NCT04284943Recruiting
Surgery for stomach cancer and diabetes
This trial tests a surgery for early-stage stomach cancer that also aims to improve type 2 diabetes by changing how your body processes food. It might be an option if you have both conditions and are not using insulin.
SeoulAges 20–69 - NCT06619626Recruiting
Lung opening technique in obese women having gynecologic cancer surgery
This trial tests a lung opening technique (alveolar recruitment) during surgery to improve breathing in obese patients. It may help women with a moderate risk of breathing problems after gynecologic cancer surgery.
IstanbulAges 18 years+ - NCT05708417Enrolling by invitation
Weight-neutral lifestyle program for adults with obesity
This study tests a lifestyle program designed to help people with obesity make healthier changes without focusing on weight loss. You might be able to participate if you meet the basic adult and body-size criteria and are not being considered for bariatric (weight-loss) surgery.
Esbjerg, Region SyddanmarkAges 18 years+ - NCT05338944Recruiting
Dialectal behavior therapy for teens with obesity and low mood
This study tests whether Dialectal Behavior Therapy (DBT)—a structured skills-based counseling program—can help teens make healthier behavior changes. It is for teens who have obesity and mild to moderate symptoms of depression, and it checks whether they can follow the study plan.
Calgary, AlbertaAges 14–17 - NCT04715022RecruitingTeam says not enrollingPhase 1/Phase 2
Vitamin C study for insulin resistance in obesity
This early-stage study tests whether vitamin C (and possibly how your body uses it) affects blood vessel function in people with obesity and insulin resistance. You may be asked to stop certain supplements before starting so researchers can measure the effect more clearly.
Kansas City, KansasAges 35–65 - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT07223151Recruiting
A taste test to help teens drink fewer sugary sodas
This study tests whether a special way of tasting sweet drinks can help teens who love sugary beverages cut back on them. It might help you reduce sugar and improve your health.
Bloomington, IndianaAges 12–18 - NCT07748949Recruiting
Low-calorie diet and lifestyle help for type 2 diabetes
This study tests whether a low-calorie diet combined with a personalized lifestyle program can help people with type 2 diabetes reach remission, meaning their blood sugar stays normal without needing diabetes medication. It uses a smartphone app to support the program.
BangkokAges 18–70
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.