Clinical trials
Obstructive Coronary Artery Disease clinical trials
Below are recruiting obstructive coronary artery disease clinical trials, each written for real people, not researchers. We’re tracking 111 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT07180368Recruiting
Managing multiple medications in older adults
This study looks at how to better manage multiple medications in older adults with long-term health conditions. It aims to improve safety and reduce drug-related problems.
Xi'an, ShaanxiAges 65 years+ - NCT07182955Recruiting
Exercise training for chest pain with clear arteries
This research study looks at why people with chest pain but clear heart arteries have low fitness. It tests whether a home-based interval training program (short bursts of hard exercise) can improve fitness and quality of life.
Charlottesville, VirginiaAges 18–85 - NCT07116083Recruiting
Study of a new way to check branch blockages after stent placement
This trial looks at a new method called µQFR to check if there are any significant blockages in the side branches of heart arteries after a single stent has been placed. It aims to see if this method can help doctors decide if more treatment is needed.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07114393Recruiting
Better imaging to guide complex heart artery procedures
This study looks at whether using advanced imaging inside the heart arteries during complex procedures leads to better outcomes compared to current standard practice. If you have had a complex angioplasty (PCI) and your data is in a national heart registry, you may be included.
Eindhoven, North BrabantAges 18 years+ - NCT07078370Enrolling by invitation
Testing a lab-made blood vessel for heart bypass surgery
This trial tests a lab-made blood vessel (called an ATEV) used as a bypass graft during heart surgery. The ATEV is designed for people who don't have enough healthy leg vein for standard bypass grafts, and it may help restore blood flow to the heart more safely.
PoznanAges 45–75 - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT07068399Recruiting
Shock Wave Therapy for Heart Blood Flow
This study tests if shock wave therapy can help grow new blood vessels in people with non-obstructive coronary artery disease. Researchers will use special heart MRI scans to see if the treatment improves blood flow to your heart.
Hong KongAges 18–80 - NCT07010029Recruiting
Heart vein device for angina with no blocked arteries
This trial tests a special device placed in a vein of the heart to help patients who have chest pain (angina) but no major blockages in their heart arteries. It is designed for people who have tried maximum medications but still have symptoms.
WarsawAges 18 years+ - NCT06400290Recruiting
Balloon test to find which artery causes chest pain
This study tests a new way to find which blocked heart arteries are causing your chest pain. During a stent procedure, doctors will briefly block each artery to see which one triggers your symptoms. This might help them decide which blockages to treat.
BasildonAges 18 years+ - NCT06896903Recruiting
Testing heart artery function with and without nitroglycerin
This study compares two ways of testing the small blood vessels in the heart to understand chest pain when no major blockages are found. It may help doctors learn more about why you have chest pain and how to treat it.
Plano, TexasAges 18 years+ - NCT04761991Recruiting
CMR vs CT scan for coronary artery disease
This study compares two heart-imaging tests—cardiac MRI (CMR) and CT—to see which better helps evaluate coronary artery disease in people with chest pain. You may be asked to have one of these scans as part of your heart work-up.
Leicester, LeicsAges 18 years+ - NCT06843005Recruiting
Heart CT scan study for plaque changes in mild coronary disease
This study uses repeat CT scans of the heart to see how plaque buildup changes over time in people with mild, non-blocking coronary artery disease. It may help doctors decide on better treatments to prevent future heart problems.
Nanjing, JiangsuAges 18–80 - NCT06794359Enrolling by invitation
Comparing minimally invasive vs. traditional bypass for multi-vessel heart disease
This study compares two types of heart bypass surgery for people with blockages in multiple heart arteries: a newer, less invasive technique (minimally invasive CABG) versus the traditional open-chest approach. It aims to see which approach leads to better recovery and outcomes.
São Paulo, São PauloAges 18 years+ - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Huntsville, AlabamaAges Any age - NCT06681740Recruiting
Breathing muscle training for heart disease patients
This study tests whether a special breathing exercise program can help people who have had a heart attack and a procedure to open blocked heart arteries. The exercises strengthen the muscles you use to breathe, which may improve your recovery and quality of life.
MálagaAges 18–80 - NCT06600178RecruitingPhase 1
Heart medication for women with chest pain and small vessel disease
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
Charlottesville, VirginiaAges 18 years+ - NCT06578234RecruitingPhase 4
Comparing Adenosine Doses for Heart MRI
This study will compare different doses of adenosine during a heart MRI to find the best dose for measuring blood flow to the heart muscle. It is for people with known or possible coronary artery disease or heart failure, as well as healthy volunteers.
LundAges 40 years+ - NCT06579807Recruiting
Cardiac rehab for coronary artery disease
This study tests if a cardiac rehabilitation program helps people with coronary artery disease. You can join if you are between 40 and 70, have heart disease (or are a healthy volunteer), and do not have other health issues like heart failure or smoking.
Rio de Janeiro, Rio de JaneiroAges 40–70 - NCT06434935Enrolling by invitationEarly Phase 1
Trial of a new bypass graft for heart surgery
This trial tests a new artificial blood vessel for heart bypass surgery. If you need a bypass and meet the health requirements, you may be able to receive this experimental graft.
AsunciónAges 45–75 - NCT06259019Recruiting
Blood test during heart procedure to find disease markers
This trial uses a special device to take a small blood sample from your heart arteries during a planned procedure. It aims to find unique markers that could help doctors better understand and treat coronary artery disease.
BournemouthAges 18 years+ - NCT06185530Recruiting
Comparing stress echo vs CT scan for chest pain
This trial compares two heart imaging tests (stress echo with ultrasound of the neck, and a CT scan) to see which one better helps guide treatment for people with chest pain that might be from heart disease. If you have chest pain that is typical for heart disease, you may be able to join.
Harrow, MiddxAges 18 years+ - NCT06164457Recruiting
Using patient reports to improve heart disease care
This trial tests whether asking patients to report their own symptoms and quality of life during routine heart check-ups helps doctors better care for people with coronary artery disease. You may be eligible if you are 40 or older, have known or suspected heart artery problems, and have an upcoming visit with a cardiologist.
Calgary, AlbertaAges 40 years+ - NCT05799092Recruiting
Invasive vs non-invasive test for less-severe blocked heart arteries
This study compares two approaches to evaluating and treating people with symptoms of blocked heart arteries that are not “high-risk.” It may help doctors choose the safest, most effective next step for you by comparing invasive testing versus non-invasive evaluation.
Bucheon-siAges 19 years+
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Common questions
- Are there clinical trials for obstructive coronary artery disease?
- Yes. Clin2 currently lists 111 recruiting obstructive coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Angina Patients With Non-obstructive Coronary Artery Disease
- Coronary Atherosclerosis of Native Coronary Artery
- Coronary Artery Bypass Grafting
- Multivessel Coronary Artery Disease
- Coronary Artery Bypass
- Coronary Artery Bypass Graft (CABG)
- Spontaneous Coronary Artery Dissection
- Coronary Artery Calcification
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.