Clinical trials
Obstructive Coronary Artery Disease clinical trials
Below are recruiting obstructive coronary artery disease clinical trials, each written for real people, not researchers. We’re tracking 114 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06076551Recruiting
Sex differences in small blood vessel problems of the heart
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
SeoulAges 20–80 - NCT06164457Recruiting
Using patient reports to improve heart disease care
This trial tests whether asking patients to report their own symptoms and quality of life during routine heart check-ups helps doctors better care for people with coronary artery disease. You may be eligible if you are 40 or older, have known or suspected heart artery problems, and have an upcoming visit with a cardiologist.
Calgary, AlbertaAges 40 years+ - NCT06185530Recruiting
Comparing stress echo vs CT scan for chest pain
This trial compares two heart imaging tests (stress echo with ultrasound of the neck, and a CT scan) to see which one better helps guide treatment for people with chest pain that might be from heart disease. If you have chest pain that is typical for heart disease, you may be able to join.
Harrow, MiddxAges 18 years+ - NCT06250790Recruiting
Heart Artery Check for Leg Artery Disease Patients
This trial uses a special CT scan (coronary CTA with HeartFlow analysis) to look for hidden blockages in the heart arteries of people who recently had a leg artery procedure. It may help detect heart problems early so they can be treated.
RigaAges 50 years+ - NCT06259019Recruiting
Blood test during heart procedure to find disease markers
This trial uses a special device to take a small blood sample from your heart arteries during a planned procedure. It aims to find unique markers that could help doctors better understand and treat coronary artery disease.
BournemouthAges 18 years+ - NCT06266065Recruiting
Heart vein device for chest pain not helped by medication
This trial tests a small device placed in a vein near the heart to improve blood flow and reduce chest pain in people who cannot have bypass surgery or stents. The device aims to increase the heart's oxygen supply and relieve symptoms.
ZagrebAges 18–90 - NCT06400290Recruiting
Balloon test to find which artery causes chest pain
This study tests a new way to find which blocked heart arteries are causing your chest pain. During a stent procedure, doctors will briefly block each artery to see which one triggers your symptoms. This might help them decide which blockages to treat.
BasildonAges 18 years+ - NCT06496321Recruiting
Comparing two leg vein removal methods for bypass surgery
This trial compares two ways of taking a vein from your leg during heart bypass surgery to see which causes fewer problems. The goal is to find the best method for your recovery.
MontevideoAges 18–70 - NCT06529848Recruiting
Exercise for heart symptoms with clear arteries
This trial tests if exercise training can help people who have chest pain or shortness of breath even though their main heart arteries are not blocked. It focuses on those with small vessel disease in the heart, also known as INOCA.
CopenhagenAges 50 years+ - NCT06541691Recruiting
Aspirin for heart disease patients in polluted air
This study tests if different types of aspirin (coated or chewable) and a special schedule can help people with heart or blood vessel disease when they are exposed to air pollution. If you live in Tehran and have stable heart disease, you may be able to join.
Tehran, Tehran ProvinceAges 18 years+ - NCT06546761Recruiting
Heart imaging after carotid artery treatment
This study tests whether imaging the heart's arteries with a special CT scan can help find hidden blockages in people who just had treatment for a blocked carotid artery. It aims to prevent future heart problems.
RigaAges 50 years+ - NCT06568159Recruiting
Sleep apnea treatment in heart patients
This study looks at how well people with heart disease or high heart risk follow their sleep apnea treatment, comparing a mouth device (MAD) to a CPAP machine. It aims to find which treatment works better for daily use.
MontpellierAges 18 years+ - NCT06578234RecruitingPhase 4
Comparing Adenosine Doses for Heart MRI
This study will compare different doses of adenosine during a heart MRI to find the best dose for measuring blood flow to the heart muscle. It is for people with known or possible coronary artery disease or heart failure, as well as healthy volunteers.
LundAges 40 years+ - NCT06579807Recruiting
Cardiac rehab for coronary artery disease
This study tests if a cardiac rehabilitation program helps people with coronary artery disease. You can join if you are between 40 and 70, have heart disease (or are a healthy volunteer), and do not have other health issues like heart failure or smoking.
Rio de Janeiro, Rio de JaneiroAges 40–70 - NCT06597851Recruiting
Insulin resistance and heart artery health: a study for chest pain patients
This study looks at how insulin resistance affects tiny heart arteries in people who have chest pain and signs of heart stress on tests, but do not have major blockages in their heart arteries. It aims to understand why some people have heart symptoms even when their main arteries appear clear.
Verona, VRAges 18 years+ - NCT06600178RecruitingPhase 1
Heart medication for women with chest pain and small vessel disease
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
Charlottesville, VirginiaAges 18 years+ - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06681740Recruiting
Breathing muscle training for heart disease patients
This study tests whether a special breathing exercise program can help people who have had a heart attack and a procedure to open blocked heart arteries. The exercises strengthen the muscles you use to breathe, which may improve your recovery and quality of life.
MálagaAges 18–80 - NCT06793774Recruiting
Using CT scans and AI to evaluate heart artery risk
This study uses a CT scan of your heart (CCTA) and advanced computer analysis to see how well it can predict heart risks compared to detailed inside-look tests (IVUS, OCT, NIRS). If you have chest pain and have had certain heart scans, this trial may help doctors understand your condition better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06793787Recruiting
AI and advanced imaging to guide treatment of borderline heart blockages
This study uses advanced CT scans and a special camera (OCT) to look at borderline blockages in heart arteries more closely. It aims to see if artificial intelligence can help decide which blockages need a stent and which can be treated with medicine alone.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06843005Recruiting
Heart CT scan study for plaque changes in mild coronary disease
This study uses repeat CT scans of the heart to see how plaque buildup changes over time in people with mild, non-blocking coronary artery disease. It may help doctors decide on better treatments to prevent future heart problems.
Nanjing, JiangsuAges 18–80 - NCT06900270Recruiting
Comparing blood markers in coronary artery disease
This study looks at blood proteins and other molecules in people with different types of coronary artery disease. The goal is to see how these markers differ between those with blocked arteries, those with narrowed arteries, and those with no artery disease. This may help doctors better understand the disease and improve treatment.
São Paulo, São PauloAges 50–80 - NCT07010029Recruiting
Heart vein device for angina with no blocked arteries
This trial tests a special device placed in a vein of the heart to help patients who have chest pain (angina) but no major blockages in their heart arteries. It is designed for people who have tried maximum medications but still have symptoms.
WarsawAges 18 years+ - NCT07068399Recruiting
Shock Wave Therapy for Heart Blood Flow
This study tests if shock wave therapy can help grow new blood vessels in people with non-obstructive coronary artery disease. Researchers will use special heart MRI scans to see if the treatment improves blood flow to your heart.
Hong KongAges 18–80
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Common questions
- Are there clinical trials for obstructive coronary artery disease?
- Yes. Clin2 currently lists 114 recruiting obstructive coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Angina Patients With Non-obstructive Coronary Artery Disease
- Coronary Atherosclerosis of Native Coronary Artery
- Coronary Artery Bypass Grafting
- Multivessel Coronary Artery Disease
- Coronary Artery Bypass
- Coronary Artery Bypass Graft (CABG)
- Spontaneous Coronary Artery Dissection
- Coronary Artery Calcification
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.