Clinical trials
Obstructive Sleep Apnea (OSAS) clinical trials
Below are recruiting obstructive sleep apnea (osas) clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06594627Recruiting
Smart pillow study for better sleep with snoring or sleep apnea
This study tests a smart pillow device to see if it can improve sleep quality for people over 50 who snore or have mild sleep apnea. It also looks at how the pillow affects sleep partners.
Indianapolis, IndianaAges 50 years+ - NCT06576310Recruiting
Predicting teeth changes from sleep apnea mouthpiece treatment
This study looks at people with sleep apnea who are using a special mouthpiece (mandibular advancement device). It aims to find out which factors predict changes in how your teeth fit together after using the device.
ToulouseAges 18 years+ - NCT06566820Enrolling by invitationPhase 3
Long-term follow-up for sleep apnea study
This is a follow-up study for people with obstructive sleep apnea who have already completed two prior studies with the same medicine. The goal is to keep tracking your health and the medicine's effects over a longer time.
Birmingham, AlabamaAges 18 years+ - NCT06559956Recruiting
Comparing two ways to adjust Inspire therapy settings
This trial compares two methods of adjusting the Inspire device settings for sleep apnea. One method uses an overnight sleep study, the other a daytime study. The goal is to see if the daytime method works just as well.
Edegem, AntwerpAges 18–99 - NCT06477952RecruitingPhase 1/Phase 2
Dronabinol for sleep apnea
This study tests whether dronabinol, a cannabis-like medicine, can help people with moderate sleep apnea breathe better at night. It may be an option for those who haven't found other treatments helpful.
Chicago, IllinoisAges Up to 65 years - NCT06312956Recruiting
Sleep Apnea and Ventilotherapy: A Study Before and After Treatment
This trial studies how sleep apnea affects the body and brain before and after starting treatment with a breathing device (ventilotherapy). It aims to understand the benefits of early treatment for people with obstructive sleep apnea.
Piancavallo, VCOAges 20–60 - NCT06462287RecruitingPhase 2
Testing a substance P blocker for high blood pressure and sleep apnea
This study tests if a drug that blocks substance P can lower a hormone called aldosterone in people with both severe sleep apnea and high blood pressure. If you have these conditions, this trial may help find a new treatment option.
Rouen, FranceAges 18–75 - NCT06471751Recruiting
Breathing and throat muscle exercises for moderate sleep apnea
This trial tests whether strengthening your breathing and throat muscles can improve moderate sleep apnea. It aims to see if these exercises help reduce breathing pauses and improve sleep quality.
GrenobleAges 18 years+ - NCT06332404Recruiting
Sleep apnea nerve stimulation therapy registry
This study is tracking how well a nerve stimulation device works for people with obstructive sleep apnea who can't use a CPAP machine. The device, called Inspire, sends mild electrical pulses to help keep your airway open while you sleep.
Edegem, AntwerpAges 18–99 - NCT06434558Enrolling by invitation
MRI predictors of cryolysis for sleep apnea
This study uses MRI scans to see how well a cold treatment (cryolysis) works for obstructive sleep apnea. It is only open to people already in the ARCTIC-3 trial at the University of Pennsylvania.
Philadelphia, PennsylvaniaAges Any age - NCT06430957Recruiting
Sleep apnea risk after dental surgery under general anesthesia
This study checks dental patients for the risk of sleep apnea before surgery and looks at whether that risk is linked to problems after general anesthesia. It may help you understand your own risk and improve safety.
KayseriAges 18–80 - NCT06380491RecruitingPhase 4
Melatonin for nighttime blood pressure in sleep apnea
This study tests whether melatonin can help lower nighttime blood pressure and improve sleep quality in people with obstructive sleep apnea who have 'non-dipping' blood pressure (blood pressure that stays high at night).
Mexico CityAges 18–60 - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Boise, IdahoAges 18 years+ - NCT06258837Recruiting
Personalized surgery for sleep apnea in children with small tonsils
This study tests a personalized surgical approach for children with moderate to severe obstructive sleep apnea who have small tonsils. The goal is to see if tailored surgery improves their breathing during sleep and overall health.
Ann Arbor, MichiganAges 2–17 - NCT06189755Recruiting
MicroRNA markers for sleep apnea
This trial is studying tiny molecules in the blood (called microRNAs) to see if they can help diagnose or monitor obstructive sleep apnea. It compares people with moderate to severe sleep apnea who are starting PAP therapy with people who do not have sleep apnea.
Columbus, OhioAges 18–75 - NCT06117579Recruiting
Breathing Muscle Training for Sleep Apnea
This trial tests whether a simple breathing exercise (training the muscles you use to breathe in) can improve sleep apnea symptoms in people who already use CPAP. The goal is to see if adding this training helps you feel better or need less CPAP pressure.
OrléansAges 18 years+ - NCT06043440RecruitingPhase 2
Oxygen therapy for sleep apnea in Down syndrome
This study tests whether oxygen therapy can help children with Down syndrome who have sleep apnea. It compares oxygen treatment to no treatment to see if it improves breathing during sleep and thinking skills.
Los Angeles, CaliforniaAges 5–18 - NCT05953610RecruitingPhase 2
Surgery study for sleep apnea when CPAP won’t work
This Phase 2 trial tests whether a specific type of palate surgery can treat moderate-to-severe obstructive sleep apnea in people who cannot tolerate CPAP (a breathing mask). It also checks patient traits (based on sleep testing) to see who is most likely to benefit from surgery.
Santa Monica, CaliforniaAges 21 years+ - NCT05917119Recruiting
Bright light therapy for obstructive sleep apnea symptoms
This study tests whether a “bright light” treatment can reduce daytime sleepiness in people with obstructive sleep apnea who are already using CPAP or BiPAP. It may help people feel more awake during the day without changing their sleep apnea device use.
Pittsburgh, PennsylvaniaAges 40–65 - NCT05939934Recruiting
Test a mouth device for sleep apnea after stopping CPAP
This study looks at whether a mandibular advancement device (a fitted mouthpiece) can control sleep apnea when you temporarily stop CPAP. It’s mainly for people who have been using CPAP for over a year but are now willing to try the mouth device.
AngersAges 18–75 - NCT05911646Recruiting
Tool to help decisions for mild sleep apnea in kids
This trial looks at OSA-18, a questionnaire that may help families and clinicians make better decisions about treatment for a child’s mild sleep apnea. It specifically focuses on children with enlarged tonsils and mild sleep study results.
Hartford, ConnecticutAges 3–12 - NCT05838183Recruiting
Test treatment in people with lung disease and sleep apnea
This trial is studying how a treatment may work for adults who have interstitial lung disease or obstructive sleep apnea. It likely involves sleep testing so the team can measure breathing and sleep patterns.
TianjinAges 18–80 - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT05147649Recruiting
Brain scan study in severe sleep apnea without CPAP
This trial uses a specialized brain scan (MRI) to study people with severe obstructive sleep apnea who are not using CPAP. It also compares them with people who do not have sleep apnea to understand how brain function differs.
ReimsAges 18–75
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Common questions
- Are there clinical trials for obstructive sleep apnea (osas)?
- Yes. Clin2 currently lists 227 recruiting obstructive sleep apnea (osas) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive sleep apnea (osas) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive sleep apnea (osas) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.