Clinical trials
Obstructive Sleep Apnea (OSAS) clinical trials
Below are recruiting obstructive sleep apnea (osas) clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05558501RecruitingPhase 1/Phase 2
Intermittent low-oxygen therapy for sleep apnea and health risks
This early-stage study tests a treatment that briefly reduces oxygen during sleep to improve “plasticity,” with the goal of helping people with obstructive or mixed sleep apnea. It also looks at related conditions like high blood pressure and pre-diabetes or cholesterol problems, especially in people who haven’t tried CPAP yet.
Detroit, MichiganAges 30–60 - NCT05606991Enrolling by invitation
Testing how CPAP affects brain waste clearance during sleep
This study looks at how stopping CPAP for 14 nights affects “brain waste clearance,” a process your brain uses to clear byproducts during sleep. It is testing whether using CPAP versus stopping it changes this brain cleanup in adults with severe obstructive sleep apnea (OSA).
Macquarie Park, New South WalesAges 35–65 - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70 - NCT05527652Recruiting
Breathing tube device to help blocked upper airways in children
This study tests a self-supporting breathing tube placed through the nose during sleep to reduce upper airway blockage and improve breathing in children. It may help children who have sleep apnea symptoms, especially after tonsil/adenoid treatment or when tonsil removal isn’t possible.
Ann Arbor, MichiganAges 3–21 - NCT05501236Recruiting
Nerve stimulation for sleep apnea using neck nerve signals
This study tests a device that stimulates nerves in the neck to help keep your airway open during sleep for obstructive sleep apnea. If you fit the safety and sleep-study requirements, it may offer an alternative approach to improving breathing at night.
Nashville, TennesseeAges 18 years+ - NCT05382754Recruiting
Home sleep testing for children being checked for sleep apnea
This trial tests whether home sleep testing can help diagnose sleep apnea in children. It is for kids who are already being referred for an in-lab sleep study at CHOP.
Philadelphia, PennsylvaniaAges 5–12 - NCT05350215RecruitingPhase 1/Phase 2
Testing atomoxetine and DAW2022 for obstructive sleep apnea severity
This study tests whether atomoxetine and DAW2022 can improve how severe obstructive sleep apnea is. It may help by changing breathing patterns during sleep, measured through physiology tests.
Boston, MassachusettsAges 21–70 - NCT05350332Recruiting
Testing how lung air volume affects airway narrowing during sleep testing
This study looks at whether changing lung air volume affects how open or blocked your upper airway is during a drug-induced sleep test (DISE). It may help guide surgical choices for people with obstructive sleep apnea (OSA).
Atlanta, GeorgiaAges 18 years+ - NCT05289063RecruitingPhase 1
Study new sleep apnea and blood vessel function
This Phase 1 study looks at how blood vessel function is affected by obstructive sleep apnea in adults who are newly diagnosed and have not used CPAP. It may help researchers understand the early effects of sleep apnea and guide future treatments.
New York, New YorkAges 18 years+ - NCT05303987RecruitingPhase 2
Dexmedetomidine or propofol for sleep endoscopy in children
This Phase 2 study compares two medicines used to help children sleep during a procedure called drug-induced sleep endoscopy. It’s for children with obstructive sleep apnea who are being evaluated before adenotonsillectomy, to help surgeons understand the cause of the blockage and potentially improve treatment planning.
Ann Arbor, MichiganAges 3–11 - NCT05293600RecruitingPhase 1/Phase 2
Rescue medicine trial for sleep apnea after other treatments fail
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
Boston, MassachusettsAges 21–70 - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05052216Recruiting
Wearable monitor study for kids’ sleep apnea
This study tests a wearable device that can help monitor breathing and sleep in children. It compares children with sleep apnea to children without sleep apnea using a simple nighttime monitoring approach.
Bethesda, MarylandAges 3–12 - NCT04991389RecruitingPhase 4
Test a breathing study plan for kids with sleep apnea after surgery
This trial studies how to improve outcomes for children who still have obstructive sleep apnea after having their tonsils and adenoids removed. It uses computer modeling (based on breathing/airflow) and may include a special breathing gas during testing in some parts of the study.
Cincinnati, OhioAges 3–18 - NCT03109171Recruiting
Test accuracy using a scope-based feeling test for sleep apnea
This study checks how accurately a special camera/scope test can measure throat sensation in people being evaluated for obstructive sleep apnea (OSA). If the test works well, it may help improve how clinicians understand and assess OSA-related changes.
Bogotá, Bogota D.C.Ages 18 years+ - NCT04814420Recruiting
Study heart scarring in sleep apnea, with or without atrial fibrillation
This pilot study looks at whether obstructive sleep apnea leads to heart scarring (called atrial fibrosis), especially in people with and without an irregular heart rhythm (atrial fibrillation). It may help researchers understand who is at higher risk and why, using sleep testing and heart imaging.
New Orleans, LouisianaAges 18–75 - NCT04538755Enrolling by invitationPhase 1/Phase 2
Testing a new drug for moderate to severe sleep apnea
This trial tests a drug called DAW2020 to see if it can improve how your body controls breathing during sleep. You may qualify if you have moderate to severe sleep apnea and are otherwise healthy.
Boston, MassachusettsAges 21–70 - NCT04335994Recruiting
Home sleep testing for people with memory trouble
This study looks at how well home sleep apnea testing works for people with cognitive impairment (memory/thinking problems) to help improve outcomes. You may be asked to do a home sleep test (and possibly an in-lab test) and will involve a caregiver if needed.
Toronto, OntarioAges Any age - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04129229Enrolling by invitation
Tongue device study for moderate-to-severe sleep apnea and snoring
This trial tests a tongue retractor device to help treat obstructive sleep apnea and reduce snoring in adults. You may be eligible if you have moderate-to-severe sleep apnea and can avoid other common treatments during the study.
Brighton, MassachusettsAges 18 years+ - NCT04092660Recruiting
Mouth guard study to reduce airway collapse in sleep apnea
This study tests whether using an anti-snoring mouth guard (a mandibular advancement appliance) can help keep your airway open during sleep if you have obstructive sleep apnea. If you’re referred for this kind of mouth guard, the trial will see if using it more regularly or in a specific way improves symptoms or breathing during sleep.
LondonAges 40–90 - NCT04112927Recruiting
Sound-based test for sleep apnea
This study uses sound recordings to detect sleep apnea while you are awake and during sleep, which could offer a simpler alternative to traditional sleep studies. If you are suspected of having sleep apnea, this trial may help improve diagnosis and monitoring.
Winnipeg, ManitobaAges 18–70 - NCT03860233RecruitingPhase 1
Oxytocin added to CPAP for obstructive sleep apnea
This early study tests whether adding oxytocin to your usual CPAP treatment improves obstructive sleep apnea. It may help see if oxytocin changes how well CPAP works or how people feel while using it.
Washington D.C., District of ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for obstructive sleep apnea (osas)?
- Yes. Clin2 currently lists 227 recruiting obstructive sleep apnea (osas) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive sleep apnea (osas) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive sleep apnea (osas) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.