Clinical trials
Open Surgery clinical trials
Below are recruiting open surgery clinical trials, each written for real people, not researchers. We’re tracking 105 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06233318Recruiting
Pain block for open heart surgery recovery
This study tests a nerve block given during open heart surgery to improve pain control. It might help patients recover with less discomfort.
Columbus, OhioAges 18 years+ - NCT06084091Recruiting
Measuring heart oxygen levels during open-heart surgery
This study measures oxygen levels in the heart muscle during open-heart surgery using a light-based technique. You may qualify if you are an adult scheduled for this surgery and can provide consent.
Helsinki, UusimaaAges 18–90 - NCT05786313Recruiting
Open-door neck surgery plan for cervical spinal narrowing
This study looks at a more tailored and standardized surgical approach for people with neck spinal narrowing and spinal cord symptoms. It may help doctors compare and improve how well surgery works for different patients.
Xi'an, Shannxi ProvinceAges 28–85 - NCT04962776RecruitingPhase 4
Carb plus nitrate drinks before gynecologic surgery
This trial compares two pre-surgery drink plans: a low-sugar/low-concentration carbohydrate drink plus nitrates versus a carbohydrate drink alone. It aims to see which plan works better for patients having open gynecologic surgery.
CairoAges 18–60 - NCT02996656Recruiting
Antibiotic prevention for skin bacteria in shoulder surgery
This study checks whether giving an antibiotic “ahead of surgery” can reduce problems from common skin bacteria (Propionibacterium acnes) during primary shoulder surgery. It may help lower the risk of infection around the new joint/repair.
Montreal, QuebecAges 18 years+ - NCT03643926Recruiting
Arthroscopic vs open surgery for ankle instability
This trial compares two surgical approaches to treat ongoing ankle “giving way” or instability. It aims to find which method works better for people whose ankle instability has lasted at least several months.
Belo Horizonte, Minas GeraisAges 18–65 - NCT06398795Recruiting
Dual-port thyroid surgery through the armpit
This trial tests a new type of minimally invasive thyroid surgery that uses two small openings under your collarbone to remove thyroid growths. It may be a good option if you want less visible scarring from your thyroid operation.
Wenzhou, ZhejiangAges 18–90 - NCT03747588Recruiting
Laparoscopic versus open surgery for pancreas cancer
This study compares two ways of doing pancreaticoduodenectomy (a major surgery to remove parts of the pancreas and nearby tissue): minimally invasive (often smaller incisions) versus open surgery. It may help clarify which approach works best when the cancer looks potentially removable.
Beijing, Beijing MunicipalityAges 18–75 - NCT07124650RecruitingPhase 4
Sore throat after neck surgery study
This study tests if a special spray can help prevent or reduce sore throat after thyroid or parathyroid surgery. It may help you feel more comfortable after your operation.
Saint PetersburgAges 18 years+ - NCT07737912Enrolling by invitation
SpinePal app for spine fusion recovery
This study tests a smartphone app called SpinePal along with a wrist fitness tracker to help you recover after spine fusion surgery. If you qualify, you'll use the app and tracker for a few months to see if they improve your recovery and reduce pain.
Lebanon, New HampshireAges 18 years+ - NCT04576169Recruiting
Comparing treatment options for a TFCC tear in the wrist
This trial looks at which treatment works best for a specific kind of wrist cartilage (TFCC) tear. It may help you choose the most effective option if you have ulnar-sided wrist pain that didn’t improve with non-surgical care.
CopenhagenAges 18–65 - NCT07346742Recruiting
Preventing infection in children's groin surgery
This study tests whether giving antibiotics through a vein and using special stitches that fight germs can help prevent infections after open groin surgery in children. It may be helpful for children having routine groin surgery as a day procedure.
Ile-Ife, Osun StateAges Up to 15 years - NCT01762813Recruiting
Study of blood/tissue markers in colorectal cancer surgery patients
This study looks at colorectal cancer patients who are planning curative surgery and collects related outcomes and lab “biomarker” information to better understand the disease. Your participation may help researchers connect test results to treatment results over time.
StavangerAges 18 years+ - NCT07317947Recruiting
Nasal tip shaping with a cartilage graft in first-time rhinoplasty
This trial tests a surgical technique that uses your own nasal cartilage to improve the shape and position of your nasal tip. It's for people having their first rhinoplasty (nose job) for cosmetic or breathing reasons.
Kafr ash ShaykhAges 18–60 - NCT07311902Recruiting
Comparing two blocks for pain after hernia repair
This trial compares two types of nerve blocks (M-Tapa block and TAP block) to see which one works better for controlling pain after open inguinal hernia repair. It may help find a better way to manage pain after surgery.
ErzurumAges 18–65 - NCT05525312Recruiting
Two breathing strategies during lung surgery for lung cancer
This trial compares two ways of managing breathing while you have surgery to remove lung cancer. It may help doctors figure out which strategy is safer and works better during the operation.
MontpellierAges 18 years+ - NCT06631872Recruiting
Surgery school prehabilitation via telehealth for lung or abdominal cancer
This trial tests a telehealth program to help you get ready (prehab) before lung or major abdominal cancer surgery. It aims to improve your recovery and might be easier than attending in person.
New Lambton Heights, New South WalesAges 18 years+ - NCT06905015Recruiting
Comparing two methods to reduce blood loss during open liver surgery
This trial tests whether using stroke volume variation (SVV) is better than central venous pressure (CVP) to guide fluid management and reduce bleeding during open liver surgery. It aims to find a safer way to manage fluids during the operation.
Chiang Mai, ChiangmaiAges 20–70 - NCT07073937Enrolling by invitation
Three-year results of combined microstent and canaloplasty surgery
This trial is checking how well a combined eye surgery (Hydrus microstent plus canaloplasty plus cataract surgery) works over 3 years. It looks at long-term safety and effect on eye pressure. It's for people with open-angle glaucoma who already had that specific combination of procedures.
Salt Lake City, UtahAges 18 years+ - NCT07109180Recruiting
Robot vs. open surgery for chronic pancreatitis pain
This study compares robot-assisted vs. open surgery for treating chronic pancreatitis pain. It aims to see which approach works better for people with a dilated pancreatic duct who need relief from severe symptoms.
AmsterdamAges 18 years+ - NCT07780916Recruiting
Long-term results of trabectome surgery for glaucoma
This study looks at the long-term results of a specific glaucoma surgery (trabectome) done at one hospital. If you had this surgery there between 2019 and 2021, researchers want to check your eye health now to see how well it worked.
Würzburg, BavariaAges 18 years+ - NCT04553523Recruiting
Hydrus microstent study for open-angle glaucoma with cataracts
This study enrolls people who have cataracts and primary open-angle glaucoma that is being treated with eye drops. It will look at how well the Hydrus microstent works after approval, especially for lowering eye pressure safely.
Irvine, CaliforniaAges 45 years+ - NCT07485738Recruiting
Blood flow during bypass surgery and graft recovery
This study looks at how blood flow readings during coronary artery bypass surgery relate to whether the new grafts stay open and how well patients recover. It aims to help improve long-term results for people needing bypass surgery.
New York, New YorkAges 18 years+ - NCT07352683Recruiting
Nerve block for kids having belly surgery
This trial tests a nerve block to reduce pain in children aged 1–15 who are having open abdominal surgery. It aims to see if this approach improves recovery.
UppsalaAges 1–15
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Common questions
- Are there clinical trials for open surgery?
- Yes. Clin2 currently lists 105 recruiting open surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a open surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a open surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.