Clinical trials
Open Surgery clinical trials
Below are recruiting open surgery clinical trials, each written for real people, not researchers. We’re tracking 103 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07352683Recruiting
Nerve block for kids having belly surgery
This trial tests a nerve block to reduce pain in children aged 1–15 who are having open abdominal surgery. It aims to see if this approach improves recovery.
UppsalaAges 1–15 - NCT07485738Recruiting
Blood flow during bypass surgery and graft recovery
This study looks at how blood flow readings during coronary artery bypass surgery relate to whether the new grafts stay open and how well patients recover. It aims to help improve long-term results for people needing bypass surgery.
New York, New YorkAges 18 years+ - NCT07212777Recruiting
Custom vs standard knee surgery for knee alignment
This study compares a custom 3D-printed surgical guide to the standard technique for a knee realignment surgery called high tibial osteotomy. It is for people with knee arthritis on the inner side of the knee who have not improved with other treatments.
MálagaAges 18–70 - NCT07230535Recruiting
Robotic vs standard mastectomy with DIEP reconstruction study
This trial compares how patients feel after open or robotic mastectomy combined with immediate DIEP flap reconstruction. It aims to see which approach improves wellbeing and recovery for women having this surgery.
BeaumontAges 18 years+ - NCT05339984Recruiting
MRI-based planning during liver surgery and related procedures
This study uses MRI imaging and computer modeling to better plan liver surgery and related liver treatments. It may help doctors predict circulation (blood flow) changes during surgery and choose safer surgical timing or approaches.
Villejuif, Val de MarneAges 18 years+ - NCT06979752Recruiting
Testing a new cannula for glaucoma-cataract surgery
This trial tests whether a special cannula can help protect the eye during combined surgery for pseudoexfoliative glaucoma (a type of glaucoma with flaky deposits) and cataracts. It may offer better results than standard irrigation.
AvranchesAges 18 years+ - NCT05432245Enrolling by invitation
Glaucoma implant placed during cataract surgery
This trial looks at whether placing a small glaucoma implant at the same time as cataract surgery can better control eye pressure in people with primary open-angle glaucoma. It may help reduce the need for medicines or improve control, depending on how your eyes respond.
Panama CityAges 40 years+ - NCT06716073Recruiting
Endoscopic vs standard breast-conserving surgery after chemo
This study compares two types of breast-conserving surgery for women who have already had chemotherapy before their operation. It aims to see if using a tiny camera (endoscope) leads to equally good long-term results as standard breast-conserving surgery.
Guangzhou, GuangdongAges 18–75 - NCT04706026Recruiting
Local numbing during groin hernia surgery in older adults
This study tests whether using local numbing (rather than general anesthesia) during groin hernia surgery is safe and effective for older adults. It may help improve comfort and reduce anesthesia-related risks in people who qualify.
Dallas, TexasAges 60 years+ - NCT05439161Recruiting
XEN gel stent compared with trabeculectomy for open-angle glaucoma
This trial compares two glaucoma operations to see which works better at lowering eye pressure and keeping the eye stable. It’s for adults with open-angle glaucoma who are eligible for either surgery and can attend follow-up visits.
SalzburgAges 18 years+ - NCT06803732Recruiting
Pain after robotic, endoscopic or open neck surgery for thyroid cancer
This trial compares pain levels after three different surgical methods for removing cancerous lymph nodes in the neck. It may help patients with thyroid cancer that has spread to neck lymph nodes understand which approach causes less discomfort.
Shanghai, Shanghai MunicipalityAges Any age - NCT06296173Recruiting
Lung-protective breathing tube removal after surgery
This study tests a special breathing tube removal method during surgery recovery to protect your lungs. It may help you breathe better after your abdominal surgery.
Ottawa, OntarioAges 18 years+ - NCT07142408RecruitingPhase 3
Bacteria reduction before skin cancer surgery on legs
This trial tests if reducing bacteria on your skin before skin cancer surgery on the leg can lower the risk of infection, especially for wounds left open to heal naturally.
Marlton, New JerseyAges 18 years+ - NCT06365892Recruiting
Open-label placebo for pain after scoliosis surgery
This trial tests whether taking a placebo pill that you know is a placebo (open-label placebo) can help reduce pain after spinal fusion surgery for scoliosis. It compares the placebo to standard care in adolescents aged 11-17.
San Francisco, CaliforniaAges 10–18 - NCT06693258Recruiting
Robotic vs. open thyroid surgery comparison study
This study compares two ways to remove the thyroid gland: a newer robotic method through the armpit (transaxillary robotic thyroidectomy) versus the traditional open surgery through a neck incision. It aims to see which approach leads to better recovery and fewer complications.
ParisAges 18 years+ - NCT07520500Recruiting
Comparing two surgical techniques for high anal fistula
This trial compares two surgical methods (IFOC and LIFT) for treating high anal fistulas—abnormal tunnels that form near the anus. The goal is to determine which approach works better and has fewer side effects.
Cairo, Al-Manial, Cairo, EgyptAges 18 years+ - NCT07373899Enrolling by invitation
Surgery after immunotherapy to shrink lung cancer
This study looks at whether doing surgery after immunotherapy (with or without chemo) can be less invasive than originally planned. If your lung cancer shrunk enough after treatment that you might need a smaller surgery than first thought, this trial could help find the best approach.
Beijing, ChaoyangAges Any age - NCT07303257Recruiting
Quality of life after glaucoma surgery: a patient-centered study
This study compares how different types of glaucoma surgery affect your daily life and well-being. If you need glaucoma surgery, you may join to help doctors understand which procedure works best from a patient's perspective.
LyonAges 18 years+ - NCT06293469Recruiting
Speeding up flap surgery for severe leg injuries
This trial tests whether performing flap surgery sooner after a severe leg injury below the knee leads to better outcomes. If you have an open fracture or dislocation that needs a flap, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT07220382RecruitingPhase 4
Botox injections before large hernia surgery
This trial tests if getting Botox shots in the belly muscles before hernia surgery makes the repair easier and more successful. It is for adults who need a planned, open surgery for a large ventral hernia.
Cleveland, OhioAges 18 years+ - NCT07163858Recruiting
Leg raising vs. medication for heart bypass surgery
This trial compares a simple leg-raising technique to a medicine (noradrenaline) to help keep blood pressure stable during heart bypass surgery. It may help you avoid stronger drugs and have a smoother recovery.
Caluire-et-Cuire, Auvergne-Rhône-AlpesAges 18 years+ - NCT04381611Enrolling by invitation
Study of glaucoma surgeries and laser treatments over time
This study looks at people with glaucoma or high eye pressure to understand how surgeries and laser treatments affect long-term outcomes. It may help doctors predict which treatments work best for different patients.
Lausanne, Canton of VaudAges 1–100 - NCT06827795Recruiting
Testing a new surgical tool for spine surgery
This study compares a new surgical tool, the Surgify Halo, to a standard tool used in spine surgery. It aims to see which is easier to use and performs better for removing bone during spine surgery.
New York, New YorkAges 21–85 - NCT06294613Recruiting
Robotic surgery for vitreoretinal diseases
This trial tests a robotic system for eye surgery to treat conditions like vitreous hemorrhage or macular pucker. It may help patients who need a procedure called vitrectomy under general anesthesia.
Ghent, East FlandersAges 18–85
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Common questions
- Are there clinical trials for open surgery?
- Yes. Clin2 currently lists 103 recruiting open surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a open surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a open surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.