Clinical trials
Organ Dysfunction clinical trials
Below are recruiting organ dysfunction clinical trials, each written for real people, not researchers. We’re tracking 29 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07068022Recruiting
Organ function score for pregnant and new mothers in ICU
This study is testing a new way to measure how well your organs are working if you are pregnant or have recently given birth and need care in the intensive care unit (ICU). The goal is to improve monitoring and treatment for mothers in critical care.
Avellaneda, Buenos AiresAges 18 years+ - NCT06809868Recruiting
Study of genetic elements in sepsis and aging
This trial looks at how certain genetic elements may affect the immune system in older adults with sepsis. It aims to understand why older patients may respond differently to severe infections.
San Francisco, CaliforniaAges 18 years+ - NCT05623722Recruiting
Nerve block to help organ function in severe gut sepsis
This trial studies whether an erector spinae plane nerve block (a pain-control injection near the spine) can improve organ health in adults with sepsis caused by acute gut injury. It’s meant for people sick enough to need ICU care for several days.
Guangzhou, GuangdongAges 18 years+ - NCT06380842Recruiting
Organ function after necrosectomy for pancreatitis with sepsis
This study looks at how a surgery to remove dead tissue from the pancreas (called open necrosectomy) affects organ function in patients with acute pancreatitis and sepsis. It may help doctors understand how to better treat this serious condition.
Chengdu, ChinaAges 18 years+ - NCT07119411Recruiting
Early ICU Warning System for Deterioration
This trial tests a system that gives ICU staff an early alert when a patient's condition might get worse. If you are already in the ICU, the study uses your medical data to see if the alert can help catch problems sooner.
BernAges 18 years+ - NCT05090345Recruiting
Registry for young people getting bone marrow transplants
This trial is a registry that follows children and young adults up to age 26 who are having a bone marrow transplant, to better understand complications related to blood vessel and organ injury. It may help future patients by improving how doctors predict and prevent these problems.
Rochester, MinnesotaAges birth–26 years - NCT07230886Recruiting
Reducing transplant complications with enhanced preservation
This trial tests a new way to preserve donated lungs before transplant to lower the risk of complications. It may help primary graft dysfunction, a serious lung problem after surgery.
Toronto, OntarioAges 17 years+ - NCT05206955RecruitingPhase 3
Tadalafil versus placebo for Fontan circulation problems
This study tests whether tadalafil (a daily pill) can improve blood flow and protect organs in adults who have had Fontan surgery. Participants will either receive tadalafil or a placebo, and they will be monitored during a planned heart catheter procedure.
Rochester, MinnesotaAges 18 years+ - NCT05267821RecruitingPhase 2/Phase 3
Testing anakinra to reduce inflammation in pediatric sepsis MODS
This study tests whether a medicine called anakinra can “turn down” harmful inflammation in children with severe illness from sepsis. It aims to improve organ function when multiple organs are starting to fail.
Birmingham, AlabamaAges 1 day–17 years - NCT05893030Recruiting
Monitoring pain and sleep medicines to prevent complications after surgery
This study looks at whether closely monitoring opioid and sleep medicines during and after surgery can lower organ problems and death in older adults at high risk. If you qualify, your team will track how these medicines are given to help keep you safer in the postoperative period.
AmiensAges 75 years+ - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT04444349Recruiting
CoQ10 to reduce inflammation after heart surgery
This study tests whether CoQ10 (a natural nutrient) can lessen harmful inflammation and help protect organs after cardiovascular surgery. If you qualify, you may receive CoQ10 during the surgical period and be followed for how your body responds.
Beijing, Beijing MunicipalityAges 18–90 - NCT04699279Recruiting
Statin after aortic surgery to protect heart and organs
This trial tests whether taking a cholesterol-lowering medicine (a statin) after certain aortic surgeries can reduce harmful changes in the heart and other organs. You might benefit by lowering the risk of ongoing damage after your acute aortic condition and surgery.
Guangzhou, GuangdongAges 18–85 - NCT04920565Recruiting
Hemoperfusion with Polymyxin B for septic shock after heart surgery
This trial studies a blood-filter treatment (hemoperfusion with Polymyxin B) to reduce harmful substances in the blood for people who develop septic shock after heart surgery. It may help by lowering inflammation and improving safety, but it also requires meeting specific signs of severe infection and blood/bleeding conditions.
MoscowAges 18–80 - NCT05339529Recruiting
Thymosin A1 to help protect organs after emergency aortic surgery
This study looks at whether thymosin A1 can reduce immune-related problems and organ injury after emergency surgery for an acute aortic condition. If you qualify, you may receive thymosin A1 as part of the treatment plan to see if it improves recovery.
Bengbu, AnhuiAges 18–90 - NCT06195267Recruiting
Sivelestat for lung protection during emergency aortic surgery
This study tests whether a drug called sivelestat can protect your lungs and other organs during emergency surgery for a very serious aortic tear. If you qualify, you would receive the drug or a placebo right before and after surgery.
BeijingAges 18–90 - NCT06473844Recruiting
SGLT2 inhibitors for adults with sepsis
This trial tests whether a type of diabetes medicine (SGLT2 inhibitors) can help adults with sepsis, a life-threatening response to infection. If you have new-onset sepsis and can take oral medicine, you may be eligible.
Hong Kong, Hong KongAges 18 years+ - NCT06476171Recruiting
Blood test study for heart surgery patients
This study looks at blood test results from people having heart surgery with a heart-lung machine. It will help doctors understand and improve the use of these tests.
MoscowAges 18–80 - NCT07085455Recruiting
Timing of IV nutrition in critically ill patients
This trial tests whether giving IV nutrition (supplemental parenteral nutrition) at different times helps critically ill patients who are not getting enough calories from tube feeding alone. It may improve recovery for people with organ failure in the ICU.
Changchun, JilinAges 18 years+ - NCT07532174Recruiting
Blood-Cleaning Device During Heart Surgery
This trial tests a special blood-filtering device (Efferon LPS) used during heart surgery to reduce inflammation and improve recovery. The device removes harmful substances from your blood during the operation.
BarnaulAges 18 years+ - NCT06966687Enrolling by invitation
Ulinastatin and thymosin for immune support after aortic dissection surgery
This trial tests whether two anti-inflammatory drugs, ulinastatin and thymosin α1, can help protect your immune system and organs after emergency surgery for a torn aorta (aortic dissection). If you qualify and take part, you may receive these medications in addition to standard care.
Beijing, Beijing MunicipalityAges 18–80 - NCT04444362Enrolling by invitation
Probacine to protect organs after cardiovascular surgery
This study tests whether a medicine called Probacine can help protect your gut and organs after cardiovascular surgery. If you qualify, you may be asked to take part and follow the study plan to see if complications are reduced.
Beijing, Beijing MunicipalityAges 18–90 - NCT07104292Recruiting
Pelvic floor exercises for first-time moms
This study tests whether doing pelvic floor muscle exercises during early pregnancy can help strengthen the muscles that support the bladder, uterus, and bowel. If you join, you'll follow a guided exercise program from home using your phone or computer.
Aabenraa, Southern DenmarkAges 18 years+ - NCT07426770Recruiting
Outpatient rehab vs. self-training for postpartum pelvic floor health
This trial compares two ways to help women recover from pelvic floor issues after childbirth: a structured outpatient rehab program vs. a self-training program at home. It aims to see which is better for treating and preventing problems like leakage or poor muscle tone.
VilniusAges 18–50
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Common questions
- Are there clinical trials for organ dysfunction?
- Yes. Clin2 currently lists 29 recruiting organ dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a organ dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a organ dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.