Clinical trials
Osteoarthritis Knees Both clinical trials
Below are recruiting osteoarthritis knees both clinical trials, each written for real people, not researchers. We’re tracking 395 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06096259RecruitingPhase 2
Preventing knee arthritis after ACL injury
This trial tests whether metformin, a common diabetes medicine, can prevent arthritis after an ACL injury. If you are planning to have ACL surgery soon, you may be able to join.
Atlanta, GeorgiaAges 18–45 - NCT06105788Recruiting
Exercise and pain relief for knee arthritis
This study looks at how moving your arms and legs might help reduce pain for people with knee osteoarthritis. If you join, you will do some light exercise so researchers can see if it helps your knee feel better.
El Paso, TexasAges 45–90 - NCT06166628Recruiting
Comparing two procedures for knee osteoarthritis pain
This study compares two minimally invasive procedures—embolization (blocking blood flow) and nerve ablation (blocking pain signals)—to see which works better for knee osteoarthritis pain. If you have long-lasting knee pain and are considering knee replacement surgery, this trial may help find another option.
Kingston, OntarioAges 40 years+ - NCT06184451Recruiting
TENS with exercise for knee osteoarthritis
This study tests if adding TENS (a pain-relieving electrical stimulation) to a standard exercise program helps people with knee osteoarthritis feel better and move better.
São PauloAges 40–75 - NCT06191848RecruitingPhase 4
Tirzepatide for obesity and knee osteoarthritis
This trial tests a once-weekly injection called tirzepatide to help people with obesity and severe knee osteoarthritis lose weight and potentially reduce knee pain. It may be a good option if you're already waiting for knee replacement surgery and have struggled to lose weight in the past.
Fitzroy, VictoriaAges 18 years+ - NCT06196567Recruiting
Pulsed magnetic therapy for knee strength before replacement
This study tests whether pulsed electromagnetic field therapy (a non-invasive treatment using magnetic pulses) can improve muscle strength and function in people with severe knee osteoarthritis who are waiting for knee replacement surgery. It may help you feel stronger and move better before your operation.
Hong Kong, NEW TerritoriesAges 50–100 - NCT06208631Recruiting
Movement retraining for knee osteoarthritis pain
This study tests a movement retraining program to see if changing how you walk can reduce stress on your knee and ease osteoarthritis pain. It’s a good fit for people with mild knee pain who want a non-surgical option.
Stanford, CaliforniaAges 18 years+ - NCT06228573Recruiting
Brain stimulation and yoga for knee pain
This study combines a gentle brain stimulation technique (tDCS) with yoga to see if it helps reduce knee pain and improve movement in people with knee osteoarthritis.
Hamilton, OntarioAges 45 years+ - NCT06245109RecruitingPhase 4
Pain medicine study for knee osteoarthritis
This study tests how well different pain medicines work for knee osteoarthritis and looks at brain patterns to understand why some people get more relief. It may help you find a treatment that works best for you.
Chicago, IllinoisAges 41 years+ - NCT06251167Recruiting
Shoe insoles for knee osteoarthritis
This study tests whether shoe insoles can help people with knee osteoarthritis. You might be eligible if you have had knee pain for at least 6 months, your pain is at least moderate, and you also have pain in the same foot.
Vancouver, British ColumbiaAges 50 years+ - NCT06357741Recruiting
Desuzumab for knee osteoarthritis
This study tests a new medicine called Desuzumab for knee osteoarthritis. It looks at whether the medicine can help reduce pain and improve joint function.
Wuhan, HubeiAges 45–75 - NCT06384898Recruiting
Remote Tai Chi for Knee Osteoarthritis
This study tests whether doing Tai Chi (a gentle exercise) remotely from home, twice a week for 12 weeks, can help reduce knee pain and improve function in people with knee osteoarthritis. You would be assigned to either the Tai Chi group or a routine care group that avoids Tai Chi during the study.
Boston, MassachusettsAges 50–100 - NCT06414473RecruitingPhase 1/Phase 2
CBD for knee osteoarthritis pain
This study tests whether a CBD (cannabidiol) product can help reduce pain and improve daily life for people with knee osteoarthritis. If you have moderate to severe knee pain and haven't used cannabis recently, you may be able to join.
Gainesville, FloridaAges 40–75 - NCT06451510Recruiting
Knee osteoarthritis study in Northern Sweden
This trial studies knee osteoarthritis in people from Norrbotten, Sweden, who broke their tibial plateau between 2001 and 2015. It aims to understand how the injury affects the knee over time.
Luleå, Norrbotten CountyAges 18 years+ - NCT06463847RecruitingPhase 1
Stem cell therapy for knee osteoarthritis
This trial tests a new stem cell treatment (UC-MSCs) for knee osteoarthritis. It aims to see if this treatment is safe and can help reduce pain and improve knee function.
Wuhan, HubeiAges 50–70 - NCT07575555Recruiting
Lipedema's role in knee arthritis in women
This study compares women with knee arthritis who do or don't have lipedema (a condition causing painful fat buildup, usually in the legs) to understand how lipedema affects knee joint health. Results may help doctors better treat knee arthritis in women with lipedema.
Izmir, İzmirAges 30–65 - NCT06502587Recruiting
Blood flow restriction with low-intensity exercises for knee osteoarthritis
This study tests if using a special cuff to slightly reduce blood flow while doing gentle exercises can help reduce knee pain and improve function in people with knee osteoarthritis. It may offer a way to get stronger without heavy weights.
Lahore, Punjab ProvinceAges 40–65 - NCT06511557Recruiting
Virtual reality vs. leg exercises for knee arthritis
This study compares virtual reality exercises with standard leg-strengthening moves to see which better reduces pain and improves function in people with knee osteoarthritis (OA).
Rawalpindi, Punjab ProvinceAges 50 years+ - NCT06514716Recruiting
Steroid shot vs. standard procedure for knee arthritis
This study tests whether a corticosteroid shot (a strong anti-inflammatory medicine) into the knee joint works better than the standard GAE procedure for people with knee osteoarthritis. It aims to see which approach provides better pain relief and function.
ZagazigAges 18–80 - NCT06514703Recruiting
CT vs. X-ray Guided Nerve Ablation for Knee Arthritis
This study compares two different image-guided techniques (CT scan vs. fluoroscopy) to perform a nerve ablation procedure that blocks pain signals from the knee. It aims to find which method works better for reducing pain in people with knee osteoarthritis.
Zagazig, Sharqia ProvinceAges 45–80 - NCT06563258Recruiting
Balance training vs vibration therapy for knee arthritis
This study compares two types of exercise therapy—balance training and whole-body vibration—to see which helps knee pain and function better. It is for people with moderate knee osteoarthritis who have not found relief from other treatments.
CairoAges 40–60 - NCT06570291RecruitingPhase 3
Stem cell injection for knee osteoarthritis
This trial tests a new treatment using donor stem cells injected into the knee for people with moderate knee osteoarthritis. It aims to see if these cells can reduce pain and improve function.
Shanghai, ChinaAges 40–75 - NCT06574191Recruiting
Knee osteoarthritis study: pain and health outcomes
This study looks at how knee pain from osteoarthritis affects your daily life and health. You'll use a topical anti-inflammatory gel and answer questions by text or email for two months.
Sacramento, CaliforniaAges 50 years+ - NCT06576557Recruiting
Exercise and education for knee pain from meniscal tear
This study tests whether a special exercise and education program, designed by experts, can help people with knee pain from meniscal tears or early arthritis feel better and move better. It is run by a university and involves working with your GP and a physiotherapist.
Tralee, KerryAges 35–69
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Common questions
- Are there clinical trials for osteoarthritis knees both?
- Yes. Clin2 currently lists 395 recruiting osteoarthritis knees both studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis knees both trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis knees both trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.